プロフィール詳細

プロジェクトを作成

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Dr. Kianoosh N.に依頼

Canada

PhD Candidate in Bioinformatics

プロフィール概要

I am a PhD candidate in Biomedical Engineering with a background in bioinformatics. My research focuses on bioinformatics, multi‑omics analysis, Raman spectroscopy, and biomedical data science. My academic background spans a Master’s in Bioinformatics and a Bachelor’s in Cellular & Molecular Biology, grounding my work at the interface of computation and experiment. My projects include end‑to‑end analysis of lipidomics, transcriptomics, and metagenomics datasets for biomarker discovery and disease mechanism insight, as well as spectral modeling in Raman‑based diagnostics and liquid biopsy research. Alongside computational work, I bring practical wet‑lab experience: DNA/RNA/protein extraction, human cell culture, sample preparation, and experimental design/QC for molecular and imaging studies. This dual perspective helps align data pipelines with assay constraints, improve data quality at the source, and translate results into experimentally testable hypotheses. Beyond research, I have served as a journal reviewer, presented at computational oncology and biomedical meetings, and mentored students in study design, data analysis, and scientific communication. I collaborate effectively with clinicians, bench scientists, and data teams to deliver rigorous, reproducible outputs. I’m particularly interested in data‑driven biomedical research that bridges discovery and translation—integrating diverse biological datasets with experimental evidence to generate robust, decision‑ready insights for diagnostics, precision health, and therapeutic development.

専門分野

• ☆ Chemoinformatics
• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Mathematical Biology
• ☆ Biochemistry
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Lipidomics
• ☆ Genomics
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Synthetic Genomics
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Exome Sequencing
• ☆ RNA Sequencing
• ☆ ChIP-Seq
• ☆ Cell Biology
• ☆ Gene Regulation
• ☆ Bioinformatics
• ☆ Structural Bioinformatics
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ R
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Bioanalytical Testing
• ☆ Pharmacogenomics
• ☆ Pharmaceutical Manufacturing
• ☆ Bioprocess Development
• ☆ Small Molecule Manufacturing
• ☆ Clinical Trials
• ☆ Clinical Trials Data Analysis
• ☆ Human Biology
• ☆ Precision Medicine
• ☆ Health Informatics
• ☆ Immunotherapy
• ☆ Cancer Research
• ☆ Pharmaceutical Management
• ☆ Pharmaceutical Technology
• ☆ Research Methodology

サービス

• Consulting
• Data & AI

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Researcher

Toronto Metropolitan University

6月 2025 - 現在

Researcher

Institute for Biomedical Engineering, Science and Technology (iBEST)

6月 2025 - 現在

Bioinformatics Researcher

University of Manitoba

9月 2024 - 現在

Researcher

University of Helsinki

5月 2024 - 4月 2025

Researcher

Tarbiat Modares University

1月 2022 - 10月 2023

学歴

Ph.D. (Biomedical engineering)

Toronto Metropolitan University

6月 2025 - 現在

Ph.D. Student (Biomedical Engineering / Professor Venkat lab)

Toronto Metropolitan University

5月 2025 - 現在

PhD Biomedical Engineering

Toronto Metropolitan University (Formerly Ryerson)

1月 2025 - 現在

Bioinformatics (Biology)

Tarbiat Modares University

2021 - 2023

Cellular and Molecular Biology (Biology)

Islamic Azad University

2017 - 2021

認定資格

• Machine Learning for biomedical data

  Tarbiat Modares University

  1月 2022 - 現在

出版物

PREPRINT

Kianoosh Naghibzadeh, Saeid Ghavami, Courtney Clark, Amir Barzegar Behrooz, Simone da Silva Rosa, Mehdi Eshraghi, Jaodi Jacibs, Xiaohui Weng, Abhay Srivastava, Rui Vitorino, et al. (2026). BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma .

CONFERENCE PRESENTATION

Kianoosh Naghibzadeh, Shahla Shojaei, Amir Barzegar Behrooz, Rui Vitorino, Abhay Srivastava, Sanjiv Dhingra, Saeid Ghavami (2025). From lipid remodeling to therapeutic failure: the role of Cholesterol and autophagy in glioblastoma resistance . Computational Oncology and Personalized Medicine COPM2025.

Kianoosh Naghibzadeh, Javad Alizadeh, Simone C. da Silva Rosa, Behrooz Amir Barzegar, Amir Ravandi, Rui Vitorino, Naseer Ahmed, Biniam Kidane, Saeid Ghavami (2025). Loss of BCL2L13 and ceramide dysregulation may define lymphatic spread and survival in lung cancer . Computational Oncology and Personalized Medicine COPM2025.

JOURNAL ARTICLE

(2023). AI Accuracy in Papilledema Diagnosis in Fundus Photographs within 201 Eyes . Biomedical Journal of Scientific & Technical Research.

(2023). Association Study of Aspirin and Atorvastatin with Covid-19 Hospitalization: A Retrospective Longitudinal Study in Tehran . Biomedical Journal of Scientific & Technical Research.

Bita Shalbafan, Seyed Kianoosh Naghibzadeh, Hajar Aminzadeh, Hossein Lanjanian, Bardia D Baloutch, Katayon Berjis, Hamid Sajjadi (2023). Case Report: An IIH Induced Endometriosis that Diagnosed by OCT, and Revealed Ten Years Dilemma of HPG Axis Dysfunction due to Pressure Effect of CSF on Pituitary Stalk . Mathews Journal of Neurology.

Bita Shalbafan, Seyed Kianoosh Naghibzadeh, Hajar Aminzadeh, Hossein Lanjanian, Bardia D Baloutch, Hamid Sajjadi (2022). Case Report: Optical Coherence Tomography, as a Non-Invasive Approach to Evaluate Intracranial Pressure in Normal Pressure Hydrocephalus Patients, as with their Treatment Follow-ups and VP Shunts Reprogramming Procedures . Mathews Journal of Neurology.

Haicui Wang, Ayşe Kaçar Bayram, Rosanne Sprute, Ozkan Ozdemir, Emily Cooper, Matthias Pergande, Stephanie Efthymiou, Ivana Nedic, Neda Mazaheri, Katharina Stumpfe, et al. (2019). Genotype-Phenotype Correlations in Charcot-Marie-Tooth Disease Due to MTMR2 Mutations and Implications in Membrane Trafficking . Frontiers in Neuroscience.