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プロフィール詳細
Dr. Klaus-Ulrich L.に依頼
Germany
Freelance consultant MDx, PGx, Medical/Scientific writing, Biotechnology, Life Sciences with 20+ yrs experience
プロフィール概要
専門分野
サービス
Writing
Clinical Trial Documentation,
Technical Writing,
Newswriting
Research
Market Research,
Feasibility Study,
Fact Checking,
Gray Literature Search,
Systematic Literature Review,
Secondary Data Collection
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis
職務経験
Head Research & Development; Senior Clinical Research Specialist (SCRS), Pharmacogenomics
bio.logis GmbH and bio.logis Genetic Information Management GmbH, Frankfurt am Main, Germany
7月 2009 - 現在
Head Molecular Genetics
BIOSCIENTIA Institute of Medical Diagnostics, Center for Human Genetics, Ingelheim, Germany
8月 2001 - 6月 2009
Vice President Molecular Genetics
GenProfile AG, Berlin
2月 2000 - 7月 2001
Lab Director Molecular Neurogenetics
Center for Psychobiological and Psychosomatic Research, University of Trier
7月 1995 - 1月 2000
Senior Research Scientist
Max-Planck-Institute for Biophysical Chemistry, Department of Membrane Biophysics (Prof. Dr. Erwin Neher),Göttingen
4月 1993 - 7月 1995
Senior Research Scientist
Transgene SA, Strasbourg France
4月 1989 - 4月 1993
学歴
PhD Biochemistry, Molecular Genetics
Institute of Organic Chemistry and Biochemistry (Prof. Dr. K. Sandhoff) and Institute of Human Genetics (Prof. Dr. P. Propping), University Bonn, Germany; NINCDS/NIH Bethesda, USA (Dr. Craig Venter)
6月 1984 - 10月 1988
Research Scientist, Research Fellow of the DAAD
National Institutes of Health (NIH), NINCDS, Section of Receptor Biochemistry and Molecular Neurobiology, Dr. J. Craig Venter
9月 1985 - 12月 1987
Diploma Chemistry
University Bonn
10月 1975 - 7月 1982
認定資格
出版物
JOURNAL ARTICLE
(2004). Gene variants and binge eating as predictors of comorbidity and outcome of treatment in severe obesity . Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.
(2004). G protein polymorphisms do not predict weight loss and improvement of hypertension in severely obese patients . Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.
(2003). Binge eating as a major phenotype of melanocortin 4 receptor gene mutations . The New England journal of medicine.
(2000). Quality assurance in RT-PCR-based BCR/ABL diagnostics--results of an interlaboratory test and a standardization approach . Leukemia.
(2000). Functional characterization of the 5'-flanking and the promoter region of the human UCP3 (hUCP3) gene . Life sciences.
(1999). Molecular cloning and functional characterization of the promoter region of the human uncoupling protein-2 gene . Biochemical and biophysical research communications.
(1999). Structural organization and mutational analysis of the human uncoupling protein-2 (hUCP2) gene . Life sciences.
(1999). Genomic organization and mutational analysis of the human UCP2 gene, a prime candidate gene for human obesity . Journal of receptor and signal transduction research.
(1997). Beta 3-adrenergic-receptor allele distributions in children, adolescents and young adults with obesity, underweight or anorexia nervosa . International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
(1997). Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa . Life sciences.
(1997). Evaluation of a Cys23Ser mutation within the human 5-HT2C receptor gene: no evidence for an association of the mutant allele with obesity or underweight in children, adolescents and young adults . Life sciences.
(1996). A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels . The Journal of neuroscience : the official journal of the Society for Neuroscience.
(1995). Physiological and molecular characterization of an IRK-type inward rectifier K+ channel in a tumour mast cell line . Pflugers Archiv : European journal of physiology.
(1994). Pharmacological characterization of the cloned kappa opioid receptor as a kappa 1b subtype . Neuroreport.
(1993). Genetic polymorphism of the beta-2 adrenergic receptor in atopic and non-atopic subjects . Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
(1993). Structure-activity analysis of synthetic alpha-thrombin-receptor-activating peptides . The Biochemical journal.
(1993). Hydrophobic cluster analysis of G protein-coupled receptors: a powerful tool to derive structural and functional information from 2D-representation of protein sequences . Journal of receptor research.
(1988). Limited tryptic proteolysis of the benzodiazepine binding proteins in different species reveals structural homologies. Journal Neurochemistry.
(1988). Dra I identifies a two allele DNA polymorphism in the human alpha 2-adrenergic receptor gene (ADRAR), using a 5.5 kb probe (p ADRAR) . Nucleic acids research.
(1988). A biallelic DNA polymorphism of the human beta-2-adrenergic receptor detected by Ban I-Adrbr-2 . Nucleic acids research.
(1988). Evolution of neurotransmitter receptor systems . Progress in neurobiology.
(1987). Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family . Proceedings of the National Academy of Sciences of the United States of America.
(1987). Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors . FEBS letters.
(1986). Qualitative variation of photolabelled benzodiazepine receptors in different species . Neurochemistry international.
(1986). Receptor variation as a source of differential response to centrally acting agents: phylogenetic evidence. Progress in clinical and biological research.
(1986). Genetic studies at the receptor level: investigations in human twins and experimental animals . Ciba Foundation symposium.
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