プロフィール詳細

プロジェクトを作成

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Dr. Lorna C.に依頼

United States

Phd scientist

プロフィール概要

PhD scientist with over 15 years experience in drug discovery and development, including 8 years in startup, biotech and big pharma environments.

専門分野

• ☆ Biology/Life Sciences
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Proteomics
• ☆ Biotechnology & Bioengineering
• ☆ Protein/Enzyme Engineering
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Phenotypic Assays
• ☆ High Content Screening/Imaging
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Drug Efficacy Testing
• ☆ Ophthalmology
• ☆ Oncology
• ☆ Immunotherapy

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, General Proofreading & Editing

Research Feasibility Study, Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Analysis

職務経験

Associate Director

Moderna Inc

5月 2023 - 8月 2025

Senior Scientist

Cyteir Therapeutics

5月 2019 - 2月 2023

Scientist

Celgene

5月 2016 - 11月 2017

Instructor

Harvard Medical School

4月 2013 - 3月 2016

Postdoctoral fellow

Boston Children's Hospital

4月 2008 - 3月 2013

学歴

Ph.D. - Clinical Pharmacology

Royal College of Surgeons in Ireland

3月 2000 - 1月 2005

Bachelors - Pharmacology

University College Dublin

9月 1995 - 5月 1999

認定資格

• PhD

  Rcsi

  6月 2005 - 現在

出版物

JOURNAL ARTICLE

Cryan, L.M.(2013). 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2 . Journal of Medicinal Chemistry. 56. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1940-1945.

Cao, S.(2012). Phenolic compounds as antiangiogenic CMG2 inhibitors from costa rican endophytic fungi . Bioorganic and Medicinal Chemistry Letters. 22. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5885-5888.

Rogers, M.S.(2012). A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 protein . PLoS ONE. 7. (6).

Walshe, T.E.(2011). The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation . Cardiovascular Research. 89. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 661-670.

Cryan, L.M.(2011). Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy . Frontiers in Bioscience. 16. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1574-1588.

Walshe, T.E.(2011). Microvascular retinal endothelial and pericyte cell apoptosis in vitro: Role of hedgehog and notch signaling . Investigative Ophthalmology and Visual Science. 52. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4472-4483.

Cagney, G.(2010). Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: Application to the platelet releasate . Journal of Biomedicine and Biotechnology. 2010.

McClelland, S.(2010). Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell . Atherosclerosis. 211. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 96-102.

Cryan, L.M.(2009). Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclooxygenase . Prostaglandins Leukotrienes and Essential Fatty Acids. 81. (5-6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 401-409.

Cryan, L.M.(2008). Expression of COX-2 and prognostic outcome in uveal melanoma . Current Eye Research. 33. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 177-184.

Cryan, L.M.(2008). Proteomics as a research tool in clinical and experimental ophthalmology . Proteomics - Clinical Applications. 2. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 762-775.

Cryan, L.M.(2006). Integrative proteomics: Structure, function, and interaction - Report on the 3rd joint meeting of the British Society for Proteome Research and the European Bioinformatics Institute, July 2006 . Proteomics. 6. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5894-5897.

Cryan, L.M.(2006). COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy . Molecular Vision. 12. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 405-414.