プロフィール詳細

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Dr. María E.に依頼

Spain

Scientific Director | Genetics Consultant | Fertility Advisor | Medical writer with 10+ years of experience in R&D

プロフィール概要

Dr. María Enciso, a Reproductive Genetics specialist with an MSc in Clinical Embryology from the University of Oxford and a PhD in Cell Biology and Genetics from the Autonomous University of Madrid, boasts extensive experience in advanced molecular biology techniques. Her expertise spans various facets of human reproduction, including gamete production, embryonic development, and endometrial tissue dynamics. Throughout her career, she has conducted research projects focusing on the effects of sperm DNA damage on fertility across different mammalian species, including humans. Her postdoctoral research has centered on understanding the genetic mechanisms underlying infertility, particularly concerning genetic alterations affecting human gametes and embryos. As a scientific advisor to Reprogenetics UK, Dr. Enciso has contributed significantly to preimplantation genetic diagnostics. Her professional journey has yielded over 20 scientific publications in high-impact journals in human reproduction, along with numerous presentations at national and international conferences. She also serves as an expert reviewer for the European Commission for Research and Innovation and scientific journals in Genetics and Human Reproduction. Currently serving as the CSO Scientific Director of iGLS, a company specializing in diagnosing infertility, analyzing gametes and embryos, and personalizing assisted reproduction treatments, Dr. Enciso demonstrates proactive leadership and critical decision-making abilities. With over 20 years of experience, she has successfully developed and validated more than 10 diagnostic methods and personalized treatments, one of which holds international patent status. She has also established two clinical diagnostic labs and obtained ISO 15189 accreditations. Dr. Enciso's multidisciplinary expertise, project management skills, and dedication to advancing health sciences through innovation and collaboration underscore her commitment to the field of Genetics, Human Fertility, and Assisted Reproduction.

専門分野

• ★ Embryology
• ★ Molecular Biology
• ★ Genetics
• ☆ Developmental Biology
• ☆ Cell Biology
• ☆ Cytogenetics
• ☆ Project Management

サービス

• Writing
• Research
• Consulting
• Product Development

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Business & Legal Writing, Copywriting, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

Research Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Operations Consulting, Scientific and Technical Consulting, Regulatory Consulting

Product Development Quality Assurance & Control (QA/QC)

職務経験

Expert

BioExpert Network

1月 2024 - 現在

Lecturer MSc Human Fertility

university of alicante

10月 2015 - 現在

CSO Scientific Director

Integrated Genetic Lab Services

10月 2015 - 現在

External Expert

European Commission

1月 2015 - 現在

Researcher

University of Oxford

10月 2010 - 5月 2014

Cytogeneticist

Reprogenetics UK

10月 2010 - 5月 2014

lecturer

University of Oxford

1月 2011 - 1月 2013

PhD Researcher

Autonomous University of Madrid

10月 2003 - 1月 2010

Academic Visitor

Cleveland Clinic

10月 2007 - 1月 2008

Academic Visitor

Buenos Aires University

9月 2005 - 3月 2006

学歴

MSc Clinical Embryology

University of Oxford

9月 2009 - 6月 2010

PhD in Genetics and Cell Biology

Autonomous University of Madrid

9月 2003 - 1月 2010

Bachelor in Science, Biological Sciences

Autonomous University of Madrid

9月 1998 - 6月 2003

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Enciso M, Aizpurua J, Rodríguez-Estrada B, Jurado I, Ferrández-Rives M, Rodríguez E, Pérez-Larrea E, Climent AB, Marron K, Sarasa J (2021). The precise determination of the window of implantation significantly improves ART outcomes . Scientific reports.

Sarasa J, Enciso M, García L, Leza A, Steger K, Aizpurua J (2020). Comparison of ART outcomes in men with altered mRNA protamine 1/protamine 2 ratio undergoing intracytoplasmic sperm injection with ejaculated and testicular spermatozoa . Asian journal of andrology.

Medrano L, Enciso M, Gomez-Torres MJ, Aizpurua J (2019). First birth of a healthy infant following intra-cytoplasmic sperm injection using a new permeable cryoprotectant-free sperm vitrification protocol . Cryobiology.

Eugenia Rocafort, Enciso M, Leza A, Sarasa J, Aizpurua J (2018). Euploid embryos selected by an automated time-lapse system have superior SET outcomes than selected solely by conventional morphology assessment . Journal of assisted reproduction and genetics.

Enciso M, Carrascosa JP, Sarasa J, Martínez-Ortiz PA, Munné S, Horcajadas JA, Aizpurua J (2018). Development of a new comprehensive and reliable endometrial receptivity map (ER Map/ER Grade) based on RT-qPCR gene expression analysis . Human reproduction (Oxford, England).

Aizpurua J, Medrano L, Enciso M, Sarasa J, Alejandro Romero, Fernández MA, Gómez-Torres MJ (2017). New permeable cryoprotectant-free vitrification method for native human sperm . Human reproduction (Oxford, England).

Enciso M, Sarasa J, Xanthopoulou L, Bristow S, Bowles M, Fragouli E, Delhanty J, Wells D (2016). Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy . Human genetics.

Fragouli E, Alfarawati S, Spath K, Jaroudi S, Sarasa J, Enciso M, Wells D (2013). The origin and impact of embryonic aneuploidy . Human genetics.

Enciso M, Alfarawati S, Wells D (2013). Increased numbers of DNA-damaged spermatozoa in samples presenting an elevated rate of numerical chromosome abnormalities . Human reproduction (Oxford, England).

Enciso M, Pieczenik G, Cohen J, Wells D (2012). Development of a novel synthetic oligopeptide for the detection of DNA damage in human spermatozoa . Human reproduction (Oxford, England).

Enciso M, Iglesias M, Galán I, Sarasa J, Gosálvez A, Gosálvez J (2011). The ability of sperm selection techniques to remove single- or double-strand DNA damage . Asian journal of andrology.

Enciso M, Cisale H, Johnston SD, Sarasa J, José Luis Fernández, Jaime Gosalvez (2011). Major morphological sperm abnormalities in the bull are related to sperm DNA damage . Theriogenology.

Enciso M, Johnston SD, Gosálvez J (2011). Differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay . Reproduction, fertility, and development.

Enciso M, Sarasa J, Agarwal A, José Luis Fernández, Jaime Gosalvez (2009). A two-tailed Comet assay for assessing DNA damage in spermatozoa . Reproductive biomedicine online.

Begoña Pérez Llano, Enciso M, García-Casado P, Sala R, Jaime Gosalvez (2006). Sperm DNA fragmentation in boars is delayed or abolished by using sperm extenders . Theriogenology.

Enciso M, Muriel L, José Luis Fernández, Goyanes V, Segrelles E, Marcos M, Montejo JM, Ardoy M, Pacheco A, Jaime Gosalvez (2006). Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test . Journal of andrology.

José Luis Fernández, Muriel L, Goyanes V, Segrelles E, Jaime Gosalvez, Enciso M, LaFromboise M, Christopher De Jonge (2005). Halosperm is an easy, available, and cost-effective alternative for determining sperm DNA fragmentation . Fertility and sterility.

José Luis Fernández, Muriel L, Goyanes V, Segrelles E, Jaime Gosalvez, Enciso M, LaFromboise M, Christopher De Jonge (2005). Simple determination of human sperm DNA fragmentation with an improved sperm chromatin dispersion test . Fertility and sterility.

Enciso M, López-Fernández C, José Luis Fernández, García P, Gosálbez A, Jaime Gosalvez (2005). A new method to analyze boar sperm DNA fragmentation under bright-field or fluorescence microscopy . Theriogenology.