プロフィール詳細

プロジェクトを作成

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Dr. Mervic D.に依頼

Germany

Organic Chemist with expertise in natural products, multi-step synthesis, bioresponsive probe design, GMP, and RA.

プロフィール概要

I am a PhD-trained organic chemist with a strong background in natural products chemistry and bioresponsive compound design. Experienced in total/multi-step synthesis, enzymatic assays, and the development of probes for SAR studies, protein labeling, and drug discovery, supported by knowledge in chemical safety, Good Manufacturing Practice (GMP), Good Distribution Practice (GDP), and Regulatory Affairs (RA). Recognized for my independent and responsible work ethic, I bring a cross-disciplinary perspective aimed at driving innovation at the intersection of academic research, pharmaceutical development, and food science.

専門分野

• ☆ Natural Product Chemistry
• ☆ Analytical Chemistry
• ☆ Spectroscopy
• ☆ UV Spectroscopy
• ☆ IR Spectroscopy
• ☆ NMR Spectroscopy
• ☆ Mass Spectrometry
• ☆ Liquid Chromatography/HPLC
• ☆ Gas Chromatography
• ☆ Organic Chemistry
• ☆ Retrosynthesis
• ☆ Biochemistry
• ☆ Enzyme Activity Assays
• ☆ Food Safety
• ☆ Drug Discovery
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Drug Substance Characterization
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Health Risk Assessments
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing

Research Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting, Regulatory Consulting

Data & AI Text Mining & Analytics

Product Development Formulation, Quality Assurance & Control (QA/QC)

職務経験

Postdoctoral Researcher

University of Gothenburg Sweden

11月 2022 - 11月 2024

Ph.D. student

Technische Universität Carolo-Wilhelmina Braunschweig

1月 2021 - 9月 2022

Ph.D. student

Technische Universität Chemnitz

10月 2018 - 12月 2020

Master's Student

University of Yaounde 1

10月 2015 - 8月 2017

学歴

Ph.D. Organic Chemistry

Technische Universität Carolo-Wilhelmina Braunschweig - Germany

1月 2021 - 9月 2022

Ph.D. Organic Chemistry

Technische Universität Chemnitz - Germany

10月 2018 - 12月 2020

Masters of Science in Organic Chemistry

University of Yaounde 1

10月 2015 - 8月 2017

認定資格

• Good Manufacturing Practice (GMP)

  Svensk Medicin AB

  5月 2025 - 現在

• Chemical Hazards: Toxicology & Reactivity

  University of California, Davis

  5月 2025 - 現在

• Essentials of Regulatory Affairs (RA)

  Svensk Medicin AB

  1月 2025 - 現在

出版物

JOURNAL ARTICLE

Mervic D. Kagho, Aishi Chakrabarti, Charity S. G. Ganskow, Claire. C. Jimidar, Lorenz Wiese, Neslihan Beyazit, Ulrike Beutling, Margarita Seeger, Silvana Smits, Stella Nyström, et al. (2025). Synthesis and Evaluation of Pseudoglucosinolates Releasing Isothiocyanates in the Presence of Azoreductases . ChemBioChem.

Mervic D. Kagho, Aishi Chakrabarti, Charity S. G. Ganskow, Claire C. Jimidar, Lorenz Wiese, Neslihan Beyazit, Ulrike Beutling, Magarita Seeger, Silvana Smits, Stella Nyström, et al. (2025). Synthesis and evaluation of pseudoglucosinolates (psGSLs) releasing isothiocyanates (ITCs) in the presence of azoreductases . ChemBioChem.

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Lili Jia, Vignesh Venkatakrishnan, Luisa Mehr, Johan Bylund, Klemens Rottner, Marc Stadler, Theresia E. B. Stradal, et al. (2025). NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic . Small.

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Thomas Kaufmann, Lili Jia, Jan Faix, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn (2024). Comprehensive Cell Biological Investigation of Cytochalasin B Derivatives with Distinct Activities on the Actin Network . Journal of Natural Products.

Mervic D. Kagho, Helen Hintersatz, Andreas Ihle, Haoxuan Zeng, Hedda Schrey, Wera Colisi, Philipp Klahn, Marc Stadler, Clemens Bruhn, Tobias Rüffer, et al.(2021). Total Synthesis via Biomimetic Late-Stage Heterocyclization: Assignment of the Relative Configuration and Biological Evaluation of the Nitraria Alkaloid (±)-Nitrabirine . The Journal of Organic Chemistry. American Chemical Society ({ACS})

PREPRINT

Mervic D. Kagho, Aishi Chakrabarti, Charity S. G. Ganskow, Claire C. Jimidar, Lorenz Wiese, Neslihan Beyazit, Ulrike Beutling, Margarita Seeger, Silvana Smits, Stella Nyström, et al. (2025). Synthesis and evaluation of pseudoglucosinolates (psGSLs) releasing isothiocyanates (ITCs) in the presence of azoreductases .

Mervic D. Kagho, Claire C. Jimidar, Charity S. G. Ganskow, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Mark Brönstrup, et al. (2024). Bioresponsive pseudoGlucosinolates (psGSLs) release Isothiocyanates (ITCs) in the Presence of Nitroreductases .

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Lili Jia, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn (2024). NQO1-responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell-targeted Migrastatic .

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Thomas Kaufmann, Lili Jia, Jan Faix, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn (2024). Comprehensive cell biological investigation of cytochalasin B derivatives with distinct activities on the actin network .

Mervic D. Kagho, Katharina Schmidt, Christopher Lambert, Thomas Kaufmann, Lili Jia, Jan Faix, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn (2024). Comprehensive cell biological investigation of cytochalasin B derivatives with distinct activities on the actin network .

Mervic D. Kagho, Claire C. Jimidar, Charity S. G. Ganskow, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, et al. (2024). Bioresponsive pseudoGlucosinolates (psGSLs) release Isothiocyanates (ITCs) in the Presence of Nitroreductases .