プロフィール詳細

プロジェクトを作成

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Malihe M.に依頼

Poland

PhD in Microbial Biotechnology | Expert in Protein Expression, Purification & lab setup | Ready to collaborate

プロフィール概要

I hold a PhD in Microbial Biotechnology and bring over 15 years of experience in protein expression and purification, genetic engineering, and molecular biology. My work spans both academic and industrial settings, with a strong focus on upstream and downstream process development in bacterial and mammalian systems. I have led multiple research and development projects, coordinated teams, and designed state-of-the-art laboratories. My expertise also includes consulting on project initiation, troubleshooting low protein expression, and optimizing purification workflows. I have authored over 30 scientific publications and am passionate about translating scientific knowledge into practical, high-impact solutions.

専門分野

• ☆ Microbiology
• ☆ Virology
• ☆ Molecular Virology
• ☆ Molecular Biology
• ☆ Monoclonal Antibody Production
• ☆ Biotechnology & Bioengineering
• ☆ Microbial Biotechnology
• ☆ Industrial Biotechnology
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Development

サービス

• Writing

Writing Clinical Trial Documentation, Technical Writing

職務経験

Senior Scientist II

Selvita SA

9月 2024 - 現在

Research Team Coordinator

Pure Biologics S.A.

7月 2022 - 9月 2024

Senior Research Fellow

Sunway University

3月 2019 - 2月 2022

Postdoctoral associated

Universiti Putra Malaysia

3月 2016 - 11月 2018

Post Doctoral associated

Universiti Putra Malaysia

7月 2014 - 6月 2015

学歴

PhD/Microbial Biotechnology (Microbiology)

Universiti Putra Malaysia

1月 2008 - 9月 2013

MSc/Microbiology (Microbiology)

Universiti Putra Malaysia

6月 2005 - 2月 2008

BSc./Biology-Microbiology (Biology)

Azad Univeristy of Gorgan

1月 1996 - 7月 1999

認定資格

• Managing Projects in Organizations

  PM Experts Sp. z o.o.

  11月 2024 - 現在

• ICH Good Clinical Practice E6 (R2)

  The Global Health Network

  1月 2023 - 現在

• CRISPR/cas9 Genome Editing

  Interscience Sdn Bhd

  9月 2021 - 現在

• Responsible Care and Use of Lab Animal Course (RCULAC) Rodent

  University of Malaya

  9月 2019 - 現在

• Bacterial whole genome sequencing and data analysis

  ScienceVision Sdn Bhd

  1月 2018 - 現在

出版物

JOURNAL ARTICLE

Mohd Din, Mohd Hadzdee and Nair, Anusha and Masomian, Malihe and Mohamad Ali, Mohd Shukuri and Raja Abd. Rahman, Raja Noor Zaliha(2021). Heterologous Expression and Characterization of Plant Lipase LIP2 from Elaeis guineensis Jacq. Oil Palm Mesocarp in Escherichia coli . Catalysts. 11. (2).

(2020). Assessment of Some Immune Components from The Bioactive Crude Extract Derived from The Epidermal Mucus of Climbing Perch Anabas Testudines . Turkish Journal of Fisheries and Aquatic Sciences.

(2020). Microbial Biodegradation of Paraffin Wax in Malaysian Crude Oil Mediated by Degradative Enzymes . Frontiers in microbiology.

(2020). Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71 . Viruses.

(2020). Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection . Vaccines.

(2020). Main Structural Targets for Engineering Lipase Substrate Specificity . Catalysts.

(2020). Newly Isolated Alkane Hydroxylase and Lipase Producing Geobacillus and Anoxybacillus Species Involved in Crude Oil Degradation . Catalysts.

(2019). Impact of RNA Virus Evolution on Quasispecies Formation and Virulence . International journal of molecular sciences.

(2019). Insight into Improved Thermostability of Cold-Adapted Staphylococcal Lipase by Glycine to Cysteine Mutation . Molecules (Basel, Switzerland).

(2019). pH Shift Solubilization and Precipitation Protein Extraction from the Wastes of the Threadfin Bream, Nemipterus japonicus . Journal of Biochemistry, Microbiology and Biotechnology.

(2019). Changes of Thermostability, Organic Solvent, and pH Stability in Geobacillus zalihae HT1 and Its Mutant by Calcium Ion . International journal of molecular sciences.

(2019). An in-Silico Approach to Understanding the Structure-Function: A Molecular Dynamics Simulation Study of Rand Serine Protease Properties from Bacillus Subtilis in Aqueous Solvents . Advances in Biotechnology & Microbiology.

Masomian, M. and Rahman, R.N.Z.R.A. and Salleh, A.B.(2018). A novel method of affinity tag cleavage in the purification of a recombinant thermostable lipase from Aneurinibacillus thermoaerophilus strain HZ . Catalysts. 8. (10).

Masomian, M., Rahman, R.N.Z.R.A., Salleh, A.B.(2018). A novel method of affinity tag cleavage in the purification of a recombinant thermostable lipase from Aneurinibacillus thermoaerophilus strain HZ . Catalysts. 8. (10).

Nooh, H.M., Masomian, M., Salleh, A.B., Mohamad, R., Ali, M.S.M., Rahman, R.N.Z.R.A.(2018). Production of thermostable T1 lipase using agroindustrial waste medium formulation . Catalysts. 8. (11).

Masomian, M., Rahman, R.N.Z.R.A., Salleh, A.B., Basri, M.(2018). Solubility Analysis, Cloning and Functional Overexpression of the Lipase from Aneurinibacillus thermoaerophilus strain HZ, the First Member of True Lipases Subfamily I.9 . Applied Biochemistry and Microbiology. 54. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 269-276.

Masomian, M., Jasni, A.S., Rahman, R.N.Z.R.A., Salleh, A.B., Basri, M.(2017). Impact of signal peptide and transmembrane segments on expression and biochemical properties of a lipase from Bacillus sphaericus 205y . Journal of Biotechnology. 264. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 51-62.

Naganthran, A., Masomian, M., Rahman, R.N.Z.R.A., Ali, M.S.M., Nooh, H.M.(2017). Improving the efficiency of new automatic dishwashing detergent formulation by addition of thermostable lipase, protease and amylase . Molecules. 22. (9).

Ishak, S.N.H., Mohamad Aris, S.N.A., Halim, K.B.A., Ali, M.S.M., Leow, T.C., Kamarudin, N.H.A., Masomian, M., Rahman, R.N.Z.R.A.(2017). Molecular dynamic simulation of space and earth-grown crystal structures of thermostable T1 lipase geobacillus zalihae revealed a better structure . Molecules. 22. (10).

Veno, J., Kamarudin, N.H.A., Ali, M.S.M., Masomian, M., Rahman, R.N.Z.R.A.(2017). Directed evolution of recombinant C-terminal truncated Staphylococcus epidermidis lipase AT2 for the enhancement of thermostability . International Journal of Molecular Sciences. 18. (11).

Masomian, M., Abd Rahman, R.N.Z.R., Salleh, A.B., Basri, M.(2016). Analysis of comparative sequence and genomic data to verify phylogenetic relationship and explore a new subfamily of bacterial lipases . PLoS ONE. 11. (3).

Rahman, R.N.Z.R.A., Masomian, M., Leow, A.T.C., Ali, M.S.M.(2015). Influence of protein solution in nucleation and optimized formulation for the growth of ARM lipase crystal . Journal of Crystal Growth. 426. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 234-242.

Masomian, M., Rahman, R.N.Z.R.A., Salleh, A.B., Basri, M.(2013). A new thermostable and organic solvent-tolerant lipase from Aneurinibacillus thermoaerophilus strain HZ . Process Biochemistry. 48. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 169-175.

Dinarvand, M., Rezaee, M., Masomian, M., Jazayeri, S.D., Zareian, M., Abbasi, S., Ariff, A.B.(2013). Effect of C/N ratio and media optimization through response surface methodology on simultaneous productions of intra- and extracellular inulinase and invertase from aspergillus Niger ATCC 20611 . BioMed Research International. 2013.

Dinarvand, M., Ariff, A.B., Moeini, H., Masomian, M., Mousavi, S.S., Nahavandi, R., Mustafa, S.(2012). Effect of extrinsic and intrinsic parameters on inulinase production by Aspergillus niger ATCC 20611 . Electronic Journal of Biotechnology. 15. (4).

Masomian, M., Rahman, R.N.Z.R.A., Salleh, A.B., Basri, M.(2010). A unique thermostable and organic solvent tolerant lipase from newly isolated Aneurinibacillus thermoaerophilus strain HZ: Physical factor studies . World Journal of Microbiology and Biotechnology. 26. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1693-1701.

Rahman, R.N.Z.R.A., Masomian, M., Salleh, A.B., Basri, M.(2009). A new thermostable lipase by Aneurinibacillus thermoaerophilus strain HZ : Nutritional studies . Annals of Microbiology. 59. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 133-139.