プロフィール詳細

プロジェクトを作成

★★★★★

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☆☆☆☆☆

Dr. Margriet V.に依頼

Netherlands

Freelance Scientific and Medical Writer, European-registered toxicologist

プロフィール概要

I am an experienced scientific and medical writer, as well as a European-registered toxicologist. I have extensive knowledge of various medicinal products, medical devices, pesticides, and advanced materials. With my regulatory background and skills in managing interdisciplinary research projects, I can contribute effectively to a wide range of writing projects in the biomedical and life sciences fields.

専門分野

• ☆ Nanotechnology & Nanomaterials
• ☆ Zoology
• ☆ Mammalian Biology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Microarrays
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Stem Cell Research
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Drug Development
• ☆ Biosafety Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Oncology
• ☆ Chemotherapy
• ☆ Medical Toxicology
• ☆ Immunotherapy
• ☆ Medical Sciences
• ☆ Inflammation
• ☆ Consumer Products

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Newswriting, General Proofreading & Editing, Translation

Research Fact Checking, Scientific and Technical Research

職務経験

Scientific and medical writer

Science Lines

8月 2021 - 現在

Senior Scientific and Medical Writer and toxicologist

ScienceLines

7月 2021 - 現在

Rijksinstituut voor Volksgezondheid en Milieu

2004 - 8月 2021

Senior Researcher

National Institute for Public Health and the Environment (RIVM)

10月 2004 - 7月 2021

Toxicologist

Loders Croklaan Lipid Nutrition

2月 2003 - 9月 2004

Research assistant

Michigan State University

9月 2001 - 10月 2002

学歴

PhD in Nanotoxicology

Maastricht University

10月 2007 - 7月 2011

PhD (Toxicogenomics)

Maastricht University

2007 - 2011

MSc Biology (Toxicology)

Wageningen Universiteit en Researchcentrum

1996 - 2001

International Baccalaureate

United World College of the Atlantic

9月 1992 - 6月 1994

認定資格

• Foundation Certificate in Medical Writing

  European Medical Writing Association

  3月 2024 - 現在

• European Registered Toxicologist

  Eurotox

  1月 2006 - 現在

出版物

JOURNAL ARTICLE

Groenewold, M., Bleeker, E.A.J., Noorlander, C.W., Sips, A.J.A.M., van der Zee, M., Aitken, R.J., Baker, J.H., Bakker, M.I., Bouman, E.A., Doak, S.H., et al.(2024). Governance of advanced materials: Shaping a safe and sustainable future . NanoImpact. 35.

Ruijter, N., van der Zee, M., Katsumiti, A., Boyles, M., Cassee, F.R., Braakhuis, H.(2024). Improving the dichloro-dihydro-fluorescein (DCFH) assay for the assessment of intracellular reactive oxygen species formation by nanomaterials . NanoImpact. 35.

van der Zee, M., de Vries, C., Masa, M., Morales, M., Rayo, M., Hegger, I.(2023). Regulatory aspects of a nanomaterial for imaging therapeutic cells . Drug Delivery and Translational Research. 13. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2693-2703.

Christina Giannakou, Margriet V. D. Z. Park, Irene E. M. Bosselaers, Wim H. de Jong, Jan Willem van der Laan, Henk van Loveren, Rob J. Vandebriel, Robert E. Geertsma (2020). Nonclinical regulatory immunotoxicity testing of nanomedicinal products: Proposed strategy and possible pitfalls . WIREs Nanomedicine and Nanobiotechnology.

Fernández-Bertólez, N., Costa, C., Bessa, M.J., Park, M., Carriere, M., Dussert, F., Teixeira, J.P., Pásaro, E., Laffon, B., Valdiglesias, V.(2019). Assessment of oxidative damage induced by iron oxide nanoparticles on different nervous system cells . Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 845.

Halamoda-Kenzaoui, B., Baconnier, S., Bastogne, T., Bazile, D., Boisseau, P., Borchard, G., Borgos, S.E., Calzolai, L., Cederbrant, K., Di Felice, G., et al.(2019). Bridging communities in the field of nanomedicine . Regulatory Toxicology and Pharmacology. 106. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 187-196.

Giannakou, C., Aimonen, K., Bloois, L.V., Catalán, J., Geertsma, R.E., Gremmer, E.R., De Jong, W.H., Keizers, P.H.J., Schwillens, P.L.W.J., Vandebriel, R.J., et al.(2019). Sensitive method for endotoxin determination in nanomedicinal product samples . Nanomedicine. 14. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1231-1246.

Verschoor, A.J., Harper, S., Delmaar, C.J.E., Park, M.V.D.Z., Sips, A.J.A.M., Vijver, M.G., Peijnenburg, W.J.G.M.(2019). Systematic selection of a dose metric for metal-based nanoparticles . NanoImpact. 13. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 70-75.

Park, M.V.D.Z., Catalán, J., Ferraz, N., Cabellos, J., Vanhauten, R., Vázquez-Campos, S., Janer, G.(2018). Development of a systematic method to assess similarity between nanomaterials for human hazard evaluation purposes–lessons learnt . Nanotoxicology. 12. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 652-676.

Fernández-Cruz, M.L., Hernández-Moreno, D., Catalán, J., Cross, R.K., Stockmann-Juvala, H., Cabellos, J., Lopes, V.R., Matzke, M., Ferraz, N., Izquierdo, J.J., et al.(2018). Quality evaluation of human and environmental toxicity studies performed with nanomaterials-the GUIDEnano approach . Environmental Science: Nano. 5. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 381-397.

et al., Margriet V.D.Z. Park, Eric A.J. Bleeker, Walter Brand, Flemming R. Cassee, Merel van Elk, Ilse Gosens, Wim H. de Jong, Johannes A.J. Meesters, Willie J.G.M. Peijnenburg, Joris T.K. Quik(2017). Considerations for Safe Innovation: The Case of Graphene . ACS Nano. 11. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9574--9593. American Chemical Society ({ACS})

(2017). Considerations for Safe Innovation: The Case of Graphene . ACS nano.

Park, M.V.D.Z., Bleeker, E.A.J., Brand, W., Cassee, F.R., Van Elk, M., Gosens, I., De Jong, W.H., Meesters, J.A.J., Peijnenburg, W.J.G.M., Quik, J.T.K., et al.(2017). Considerations for Safe Innovation: The Case of Graphene . ACS Nano. 11. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9574-9593.

Brand, W., Noorlander, C.W., Giannakou, C., De Jong, W.H., Kooi, M.W., Park, M.V.D.Z., Vandebriel, R.J., Bosselaers, I.E.M., Scholl, J.H.G., Geertsma, R.E.(2017). Nanomedicinal products: A survey on specific toxicity and side effects . International Journal of Nanomedicine. 12. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6107-6129.

Giannakou, C., Park, M.V.D.Z., De Jong, W.H., Van Loveren, H., Vandebriel, R.J., Geertsma, R.E.(2016). A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements . International Journal of Nanomedicine. 11. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2935-2952.

Braakhuis, H.M., Cassee, F.R., Fokkens, P.H.B., De La Fonteyne, L.J.J., Oomen, A.G., Krystek, P., De Jong, W.H., Van Loveren, H., Park, M.V.D.Z.(2016). Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study . Nanotoxicology. 10. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 63-73.

Braakhuis, H.M., Giannakou, C., Peijnenburg, W.J.G.M., Vermeulen, J., van Loveren, H., Park, M.V.D.Z.(2016). Simple in vitro models can predict pulmonary toxicity of silver nanoparticles . Nanotoxicology. 10. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 770-779.

Hougaard, K.S., Campagnolo, L., Chavatte-Palmer, P., Tarrade, A., Rousseau-Ralliard, D., Valentino, S., Park, M.V.D.Z., de Jong, W.H., Wolterink, G., Piersma, A.H., et al.(2015). A perspective on the developmental toxicity of inhaled nanoparticles . Reproductive Toxicology. 56. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 118-140.

Delmaar, C.J.E., Peijnenburg, W.J.G.M., Oomen, A.G., Chen, J., de Jong, W.H., Sips, A.J.A.M., Wang, Z., Park, M.V.D.Z.(2015). A practical approach to determine dose metrics for nanomaterials . Environmental Toxicology and Chemistry. 34. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1015-1022.

Noorlander, C.W., Kooi, M.W., Oomen, A.G., Park, M.V.D.Z., Vandebriel, R.J., Geertsma, R.E.(2015). Horizon scan of nanomedicinal products . Nanomedicine. 10. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1599-1608.

Braakhuis, H.M., Kloet, S.K., Kezic, S., Kuper, F., Park, M.V.D.Z., Bellmann, S., van der Zande, M., Le Gac, S., Krystek, P., Peters, R.J.B., et al.(2015). Progress and future of in vitro models to study translocation of nanoparticles . Archives of Toxicology. 89. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1469-1495.

Braakhuis, H.M., Gosens, I., Krystek, P., Boere, J.A.F., Cassee, F.R., Fokkens, P.H.B., Post, J.A., van Loveren, H., Park, M.V.D.Z.(2014). Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles . Particle and Fibre Toxicology. 11. (1).

Braakhuis, H.M., Park, M.V.D.Z., Gosens, I., De Jong, W.H., Cassee, F.R.(2014). Physicochemical characteristics of nanomaterials that affect pulmonary inflammation . Particle and Fibre Toxicology. 11. (1).

De Jong, W.H., Van Der Ven, L.T.M., Sleijffers, A., Park, M.V.D.Z., Jansen, E.H.J.M., Van Loveren, H., Vandebriel, R.J.(2013). Systemic and immunotoxicity of silver nanoparticles in an intravenous 28 days repeated dose toxicity study in rats . Biomaterials. 34. (33). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8333-8343.

Park, M.V.D.Z., Verharen, H.W., Zwart, E., Hernandez, L.G., Van Benthem, J., Elsaesser, A., Barnes, C., McKerr, G., Howard, C.V., Salvati, A., et al.(2011). Genotoxicity evaluation of amorphous silica nanoparticles of different sizes using the micronucleus and the plasmid lacZ gene mutation assay . Nanotoxicology. 5. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 168-181.

Park, M.V.D.Z., Lynch, I., Ramírez-García, S., Dawson, K.A., De La Fonteyne, L., Gremmer, E., Slob, W., Briedé, J.J., Elsaesser, A., Howard, C.V., et al.(2011). In vitro evaluation of cytotoxic and inflammatory properties of silica nanoparticles of different sizes in murine RAW 264.7 macrophages . Journal of Nanoparticle Research. 13. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6775-6787.

Park, M.V.D.Z., Neigh, A.M., Vermeulen, J.P., de la Fonteyne, L.J.J., Verharen, H.W., Briedé, J.J., van Loveren, H., de Jong, W.H.(2011). The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles . Biomaterials. 32. (36). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9810-9817.

Park, M.V.D.Z., Annema, W., Salvati, A., Lesniak, A., Elsaesser, A., Barnes, C., McKerr, G., Howard, C.V., Lynch, I., Dawson, K.A., et al.(2009). In vitro developmental toxicity test detects inhibition of stem cell differentiation by silica nanoparticles . Toxicology and Applied Pharmacology. 240. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 108-116.

Park, M.V.D.Z., Lankveld, D.P.K., van Loveren, H., de Jong, W.H.(2009). The status of in vitro toxicity studies in the risk assessment of nanomaterials . Nanomedicine. 4. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 669-685.

CONFERENCE PAPER

de Wit, L., Hendriks, H., van Engelen, J., Heusinkveld, H., Kienhuis, A., Rorije, E., Woutersen, M., van der Zee, M., Jeurissen, S.(2024). New Approach Methodologies (NAMs) for ad hoc human health risk assessment of food and non-food products - Proceedings of a workshop . Regulatory Toxicology and Pharmacology. 149.

OTHER

van der Zee, M., de Vries, C., Masa, M., Morales, M., Rayo, M., Hegger, I.(2022). Regulatory aspects of a nanomaterial for imaging therapeutic cells . Research Square.

BOOK

Colognato, R., Park, M.V.D.Z., Wick, P., De Jong, W.H.(2012). Interactions with the Human Body . Adverse Effects of Engineered Nanomaterials. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3-24.