プロフィール詳細

プロジェクトを作成

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Dr. Maria João G.に依頼

Portugal

Biomedical Research Consultant | Experimental Design, Scientific Review & Strategy

プロフィール概要

Translating complex experimental data into clear, rigorous and persuasive scientific narratives is often as challenging as generating the data itself. With over a decade of laboratory-based research experience and interdisciplinary training in Chemistry and Experimental Life Sciences, my work has focused on molecular biology, bioanalytical techniques (including HPLC and LC-MS), and experimental models within infection biology and cancer research. Independent scientific review and strategic support are offered for experimental theses, research manuscripts and project development. The objective is not simple editing, but strengthening methodological robustness, sharpening scientific argumentation and ensuring conceptual coherence throughout the work. Collaboration is particularly suited to graduate students, PhD candidates and early-stage researchers seeking structured, high-level feedback to elevate the scientific quality of their projects.

専門分野

• ★ Parasitology
• ★ Carcinogenesis
• ★ Research Methodology
• ☆ Microbiology
• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Molecular Biology
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Recombinant DNA
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Stem Cell Research
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Drug Discovery
• ☆ Phenotypic Assays
• ☆ Drug Development
• ☆ Drug Efficacy Testing
• ☆ Vaccine Development
• ☆ Cancer Research
• ☆ Peer Review
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Science Communication
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Data Insights

Product Development Quality Assurance & Control (QA/QC), Concept Development

職務経験

Junior Researcher

ICETA/INSA

10月 2023 - 12月 2024

PostDoctoral Fellowship

REQUIMTE

10月 2020 - 9月 2023

PhD Fellowship

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente

11月 2015 - 12月 2019

MSc Fellowship

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente

1月 2014 - 1月 2015

Fellowship

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente

1月 2012 - 7月 2012

学歴

PhD

Universidade do Porto ICBAS

2月 2015 - 12月 2019

Masters

Universidade do Porto Faculdade de Ciências

10月 2009 - 11月 2011

Bachelor

Universidade do Porto Faculdade de Ciências

9月 2005 - 7月 2009

認定資格

• Basic Statistics in R

  VIB

  1月 2026 - 現在

• Research Methodologies in Oncology

  School of Medicine and Biomedical Sciences, Abel Salazar University of Porto

  10月 2025 - 現在

• Advanced analysis techniques

  Faculty of Sciences of University of Porto

  3月 2025 - 現在

• Flow Cytometry: from basics to clinical applications

  Faculty of Pharmacy of University of Porto

  1月 2025 - 現在

• Training course in Cell Culture

  Faculty of Medicine of University of Porto

  6月 2017 - 現在

• From the basics to LC-MS data. Acquisition and interpretation

  University of Aveiro

  6月 2016 - 現在

出版物

JOURNAL ARTICLE

Maria João Gouveia, Joana Campanhã, Francisca Barbosa, Nuno Vale (2025). From Mechanism to Medicine: Peptide-Based Approaches for Cancer Diagnosis and Therapy . Biomolecules.

Maria João Gouveia, Joana Campanhã, Francisca Barbosa, Nuno Vale (2025). From Mechanism to Medicine: Peptide-Based Approaches for Cancer Diagnosis and Therapy . Biomolecules.

Catarina Moura, Maria João Gouveia, Nuno Vale (2025). Repurposed Antipsychotics as Potential Anticancer Agents: Clozapine Efficacy and Dopaminergic Pathways in Neuroblastoma and Glioblastoma . Life.

Catarina Moura, Maria João Gouveia, Nuno Vale (2025). Repurposed Antipsychotics as Potential Anticancer Agents: Clozapine Efficacy and Dopaminergic Pathways in Neuroblastoma and Glioblastoma . Life.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). Oxidative Stress Induced by Antivirals: Implications for Adverse Outcomes During Pregnancy and in Newborns . Antioxidants.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). Oxidative Stress Induced by Antivirals: Implications for Adverse Outcomes During Pregnancy and in Newborns . Antioxidants.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). PBPK Modeling of Lamotrigine and Efavirenz during Pregnancy: Implications for Personalized Dosing and Drug-Drug Interaction Management . Pharmaceutics.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). PBPK Modeling of Lamotrigine and Efavirenz during Pregnancy: Implications for Personalized Dosing and Drug-Drug Interaction Management . Pharmaceutics.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of Viral Infection Dynamics . Vaccines.

Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of Viral Infection Dynamics @article { author = {Bárbara Costa and Maria Gouveia and Nuno Vale}, title = {Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of Viral Infection Dynamics}, journal = {Vaccines}, year = {2024}, month = {jul}, url = {https://www.mdpi.com/2076-393X/12/7/782}, doi = {10.3390/vaccines12070782} } . Vaccines.

Bárbara Costa, Maria João Gouveia, Nuno Vale (2024). Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of Viral Infection Dynamics . Vaccines.

Maria João Gouveia, Eduarda Ribeiro, Nuno Vale (2024). A Surprising Repurposing of Central Nervous System Drugs against Squamous Cell Carcinoma of the Bladder, UM-UC-5 . Pharmaceutics.

Maria João Gouveia, Eduarda Ribeiro, Nuno Vale (2024). A Surprising Repurposing of Central Nervous System Drugs against Squamous Cell Carcinoma of the Bladder, UM-UC-5 . Pharmaceutics.

A Surprising Repurposing of Central Nervous System Drugs against Squamous Cell Carcinoma of the Bladder, UM-UC-5 @article { author = {Gouveia, Maria João and Ribeiro, Eduarda and Vale, Nuno}, title = {A Surprising Repurposing of Central Nervous System Drugs against Squamous Cell Carcinoma of the Bladder, UM-UC-5}, journal = {Pharmaceutics}, volume = {16}, number = {2}, pages = {212}, year = {2024}, month = {jan}, url = {http://dx.doi.org/10.3390/pharmaceutics16020212}, doi = {10.3390/pharmaceutics16020212} } . Pharmaceutics.

Control Strategies for Carcinogenic-Associated Helminthiases: An Integrated Overview @article { author = {da Costa, José Manuel Correia and Gouveia, Maria João and Rinaldi, Gabriel and Brindley, Paul J. and Santos, Júlio and Santos, Lúcio Lara}, title = {Control Strategies for Carcinogenic-Associated Helminthiases: An Integrated Overview}, journal = {Frontiers in Cellular and Infection Microbiology}, volume = {11}, year = {2021}, month = {mar}, url = {http://dx.doi.org/10.3389/fcimb.2021.626672}, doi = {10.3389/fcimb.2021.626672} } . Frontiers in Cellular and Infection Microbiology.

Mariana Pereira, Guy Caljon, Maria João Gouveia, Louis Maes, Nuno Vale (2021). Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine . Pharmaceuticals.

Mariana Pereira, Guy Caljon, Maria João Gouveia, Louis Maes, Nuno Vale (2021). Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine . Pharmaceuticals.

Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine @article { author = {Mariana Pereira and Guy Caljon and Maria Gouveia and Louis Maes and Nuno Vale}, title = {Synthesis, Biological Activity and In Silico Pharmacokinetic Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine}, journal = {Pharmaceuticals}, year = {2021}, month = {feb}, url = {https://www.mdpi.com/1424-8247/14/3/196}, doi = {10.3390/ph14030196} } . Pharmaceuticals.

Lúcio Lara Santos, Júlio Santos, Maria João Gouveia, Carina Bernardo, Carlos Lopes, Gabriel Rinaldi, Paul J. Brindley, José M. Correia da Costa (2021). Urogenital Schistosomiasis—History, Pathogenesis, and Bladder Cancer . Journal of Clinical Medicine.

Lúcio Lara Santos, Júlio Santos, Maria João Gouveia, Carina Bernardo, Carlos Lopes, Gabriel Rinaldi, Paul J. Brindley, José M. Correia da Costa (2021). Urogenital Schistosomiasis—History, Pathogenesis, and Bladder Cancer . Journal of Clinical Medicine.

Urogenital Schistosomiasis—History, Pathogenesis, and Bladder Cancer @article { author = {Lúcio Lara Santos and Júlio Santos and Maria Gouveia and Carina Bernardo and Carlos Lopes and Gabriel Rinaldi and Paul J. Brindley and José M. Correia da Costa}, title = {Urogenital Schistosomiasis—History, Pathogenesis, and Bladder Cancer}, journal = {Journal of Clinical Medicine}, year = {2021}, month = {jan}, url = {https://www.mdpi.com/2077-0383/10/2/205}, doi = {10.3390/jcm10020205} } . Journal of Clinical Medicine.

Cell-penetrating peptides in oncologic pharmacotherapy: A review @article { author = {Vale, Nuno and Duarte, Diana and Silva, Sara and Correia, Ana Salomé and Costa, Bárbara and Gouveia, Maria João and Ferreira, Abigail}, title = {Cell-penetrating peptides in oncologic pharmacotherapy: A review}, journal = {Pharmacological Research}, volume = {162}, pages = {105231}, year = {2020}, month = {dec}, url = {http://dx.doi.org/10.1016/j.phrs.2020.105231}, doi = {10.1016/j.phrs.2020.105231}, keywords = {Cancer; Cell-penetrating peptide; clinical studies; drug delivery; pharmacotherapy} } . Pharmacological Research.

Estrogen receptors in urogenital schistosomiasis and bladder cancer: Estrogen receptor alpha-mediated cell proliferation @article { author = {Bernardo, Carina and Santos, Júlio and Costa, Céu and Tavares, Ana and Amaro, Teresina and Marques, Igor and Gouveia, Maria João and et al.}, title = {Estrogen receptors in urogenital schistosomiasis and bladder cancer: Estrogen receptor alpha-mediated cell proliferation}, journal = {Urologic Oncology: Seminars and Original Investigations}, volume = {38}, number = {9}, pages = {738.e23--738.e35}, year = {2020}, month = {sep}, url = {http://dx.doi.org/10.1016/j.urolonc.2020.04.022}, doi = {10.1016/j.urolonc.2020.04.022}, keywords = {schistosomiasis haematobia; bladder cancer; estrogen receptor} } . Urologic Oncology: Seminars and Original Investigations.

Activity of Combinations of Antioxidants and Anthelmintic Drugs against the Adult Stage of Schistosoma mansoni @article { author = {Gouveia, Maria João and Brindley, Paul J. and Gärtner, Fátima and Vale, Nuno}, title = {Activity of Combinations of Antioxidants and Anthelmintic Drugs against the Adult Stage of Schistosoma mansoni}, journal = {Journal of Parasitology Research}, volume = {2020}, pages = {1--9}, year = {2020}, month = {aug}, url = {http://dx.doi.org/10.1155/2020/8843808}, doi = {10.1155/2020/8843808}, keywords = {Schistosomiasis; Antioxidants} } . Journal of Parasitology Research.

Oxysterols of helminth parasites and pathogenesis of foodborne hepatic trematodiasis caused by Opisthorchis and Fasciola species @article { author = {Vale, Nuno and Gouveia, Maria João and Gärtner, Fátima and Brindley, Paul J}, title = {Oxysterols of helminth parasites and pathogenesis of foodborne hepatic trematodiasis caused by Opisthorchis and Fasciola species}, journal = {Parasitology Research}, volume = {119}, number = {5}, pages = {1443--1453}, year = {2020}, month = {mar}, url = {http://dx.doi.org/10.1007/s00436-020-06640-4}, doi = {10.1007/s00436-020-06640-4} } . Parasitology Research.

Current and Novel Therapies Against Helminthic Infections: The Potential of Antioxidants Combined with Drugs @article { author = {Vale, Nuno and Gouveia MJ and Gärtner, Fátima}, title = {Current and Novel Therapies Against Helminthic Infections: The Potential of Antioxidants Combined with Drugs}, journal = {Biomolecules}, volume = {10}, number = {3}, pages = {350}, year = {2020}, month = {feb}, url = {http://dx.doi.org/10.3390/biom10030350}, doi = {http://dx.doi.org/10.3390/biom10030350} } . Biomolecules.

Breast cancer: insights in disease and influence of drug methotrexate @article { author = {Yang, Vítor and Gouveia, Maria João and Santos, Joana and Koksch, Beate and Amorim, Irina and Gärtner, Fátima and Vale, Nuno}, title = {Breast cancer: insights in disease and influence of drug methotrexate}, journal = {RSC Medicinal Chemistry}, volume = {11}, number = {6}, pages = {646--664}, year = {2020}, url = {http://dx.doi.org/10.1039/d0md00051e}, doi = {10.1039/d0md00051e}, keywords = {breast cancer} } . RSC Medicinal Chemistry.

Helminth infection-induced carcinogenesis: spectrometric insights from the liver flukes, Opisthorchis and Fasciola @article { author = {Gouveia, Maria João and Pakharukova, Maria Y. and Rinaldi, Gabriel and Mordvinov, Viatcheslav A. and Brindley, Paul J. and Gärtner, Fátima and Vale, Nuno}, title = {Helminth infection-induced carcinogenesis: spectrometric insights from the liver flukes, Opisthorchis and Fasciola}, journal = {Experimental Results}, volume = {1}, year = {2020}, url = {http://dx.doi.org/10.1017/exp.2020.38}, doi = {10.1017/exp.2020.38}, keywords = { mass spectrometry; food-born trematodes; fasciola hepatica; Opisthorchiasis} } . Experimental Results.

Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts @article { author = {Gouveia MJ and Brindley, Paul J. and Rinaldi, Gabriel and Gärtner, Fátima and da Costa, José M. C. and Vale, Nuno}, title = {Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts}, journal = {Infectious Agents and Cancer}, volume = {14}, number = {1}, year = {2019}, month = {nov}, url = {http://dx.doi.org/10.1186/s13027-019-0257-2}, doi = {10.1186/s13027-019-0257-2}, keywords = {Helminth infection,; Malignancy, ; Schistosomiasis,; Opisthorchiasis; Cytochrome P450; Oxysterol} } . Infectious Agents and Cancer.

Inhibition of the Formation In Vitro of Putatively Carcinogenic Metabolites Derived from S. haematobium and O. viverrini by Combination of Drugs with Antioxidants @article { author = {Gouveia MJ and Nogueira, Verónica and Araújo, Bruno and Gärtner, Fátima and Vale, Nuno}, title = {Inhibition of the Formation In Vitro of Putatively Carcinogenic Metabolites Derived from S. haematobium and O. viverrini by Combination of Drugs with Antioxidants}, journal = {Molecules}, volume = {24}, number = {21}, pages = {3842}, year = {2019}, month = {oct}, url = {http://dx.doi.org/10.3390/molecules24213842}, doi = {10.3390/molecules24213842}, keywords = {Helminth infections; carcinogenesis; DNA adducts; CYP enzymes; antioxidants; drug combination; drug repurposing} } . Molecules.

The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni @article { author = {Gouveia MJ and Brindley, Paul J. and Azevedo, Carlos and Gärtner, Fátima and da Costa, José M. C. and Vale, Nuno}, title = {The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni}, journal = {Parasites & Vectors}, volume = {12}, number = {1}, year = {2019}, month = {jun}, url = {http://dx.doi.org/10.1186/s13071-019-3566-9}, doi = {10.1186/s13071-019-3566-9}, keywords = {Anthelmintic; Biomolecules; N-acetylcysteine; Resveratrol; Schistosomula} } . Parasites & Vectors.

Combination Anthelmintic/Antioxidant Activity Against Schistosoma Mansoni @article { author = {Gouveia, Maria João and Brindley, Paul J. and Rinaldi, Gabriel and Gärtner, Fátima and da Costa, José Manuel Correia and Vale, Nuno}, title = {Combination Anthelmintic/Antioxidant Activity Against Schistosoma Mansoni}, journal = {Biomolecules}, volume = {9}, number = {2}, pages = {54}, year = {2019}, month = {feb}, url = {http://dx.doi.org/10.3390/biom9020054}, doi = {10.3390/biom9020054}, keywords = {Schistosoma mansoni; antioxidant biomolecules; anthelmintic drug; anticancer drug; newly transformed schistosomula} } . Biomolecules.

Amino Acids in the Development of Prodrugs @article { author = {Vale, Nuno and Ferreira, Abigail and Matos, Joana and Fresco, Paula and Gouveia MJ}, title = {Amino Acids in the Development of Prodrugs}, journal = {Molecules}, volume = {23}, number = {9}, pages = {2318}, year = {2018}, month = {sep}, url = {http://dx.doi.org/10.3390/molecules23092318}, doi = {10.3390/molecules23092318}, keywords = {drug delivery; amino acid transport; in vitro and in vivo assays; prodrug design; stability studies} } . Molecules.

Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules @article { author = {Gouveia MJ and Brindley, Paul and Gärtner, Fátima and Costa, José and Vale, Nuno}, title = {Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules}, journal = {Pharmaceuticals}, volume = {11}, number = {1}, pages = {15}, year = {2018}, month = {feb}, url = {http://dx.doi.org/10.3390/ph11010015}, doi = {10.3390/ph11010015}, keywords = {Antioxidants; drug repurposing; praziquantel; schistosomiasis} } . Pharmaceuticals.

Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model @article { author = {Gouveia MJ and Pakharukova, Maria Y and Laha, Thewarach and Sripa, Banchob and Maksimova, Galina A and Rinaldi, Gabriel and Brindley, Paul J and et al.}, title = {Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model}, journal = {Carcinogenesis}, volume = {38}, number = {9}, pages = {929--937}, year = {2017}, month = {may}, url = {http://dx.doi.org/10.1093/carcin/bgx042}, doi = {10.1093/carcin/bgx042} } . Carcinogenesis.

Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance @article { author = {Vale, Nuno and Gouveia MJ and Rinaldi, Gabriel and Brindley, Paul J. and Gärtner, Fátima and Correia da Costa, José M.}, title = {Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance}, journal = {Antimicrobial Agents and Chemotherapy}, volume = {61}, number = {5}, year = {2017}, month = {mar}, url = {http://dx.doi.org/10.1128/aac.02582-16}, doi = {10.1128/aac.02582-16}, keywords = {cytochromes P450; enantiomers; metabolism; praziquantel;} } . Antimicrobial Agents and Chemotherapy.

The role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer @article { author = {Vale, Nuno and Gouveia MJ and Rinaldi, Gabriel and Santos, Júlio and Santos, Lúcio Lara and Brindley, Paul J and da Costa, José M Correia}, title = {The role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer}, journal = {Tumor Biology}, volume = {39}, number = {3}, pages = {101042831769224}, year = {2017}, month = {mar}, url = {http://dx.doi.org/10.1177/1010428317692247}, doi = {10.1177/1010428317692247}, keywords = {Schistosoma haematobium; bladder; estrogen-DNA adduct; estrogen-like metabolites; squamous cell carcinoma; urogenital schistosomiasis} } . Tumor Biology.

Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer @article { author = {Gouveia MJ and Santos, Júlio and Brindley, Paul J. and Rinaldi, Gabriel and Lopes, Carlos and Santos, Lúcio L. and da Costa, José Manuel Correia and Vale, Nuno}, title = {Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer}, journal = {Cancer Letters}, volume = {359}, number = {2}, pages = {226--232}, year = {2015}, month = {apr}, url = {http://dx.doi.org/10.1016/j.canlet.2015.01.018}, doi = {10.1016/j.canlet.2015.01.018}, keywords = {Angola; Bladder; Catechol estrogen quinone; DNA adduct; Schistosomiasis; Squamous cell carcinoma} } . Cancer Letters.

Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers @article { author = {Correia da Costa, José M. and Vale, Nuno and Gouveia MJ and Botelho, MC and Sripa, Banchob and Santos, Lúcio L. and Santos, Júlio H. and Rinaldi, Gabriel and Brindley, Paul J.}, title = {Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers}, journal = {Frontiers in Genetics}, volume = {5}, year = {2014}, month = {dec}, url = {http://dx.doi.org/10.3389/fgene.2014.00444}, doi = {10.3389/fgene.2014.00444} } . Frontiers in Genetics.

Urinary Estrogen Metabolites and Self-Reported Infertility in Women Infected with Schistosoma haematobium @article { author = {Santos, Júlio and Gouveia MJ and Vale, Nuno and Delgado, Maria de Lurdes and Gonçalves, Ana and da Silva, José M. Teixeira. and Oliveira, Cristiano and et al.}, title = {Urinary Estrogen Metabolites and Self-Reported Infertility in Women Infected with Schistosoma haematobium}, journal = {PLoS ONE}, volume = {9}, number = {5}, pages = {e96774}, year = {2014}, month = {may}, url = {http://dx.doi.org/10.1371/journal.pone.0096774}, doi = {10.1371/journal.pone.0096774} } . PLoS ONE.

Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC–MS/MS survey of soluble fraction parasite extract @article { author = {Vale, Nuno and Gouveia MJ and Botelho, Mónica and Sripa, Banchob and Suttiprapa, Sutas and Rinaldi, Gabriel and Gomes, Paula and Brindley, Paul J. and Correia da Costa, José Manuel}, title = {Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC–MS/MS survey of soluble fraction parasite extract}, journal = {Parasitology International}, volume = {62}, number = {6}, pages = {535--542}, year = {2013}, month = {dec}, url = {http://dx.doi.org/10.1016/j.parint.2013.08.001}, doi = {10.1016/j.parint.2013.08.001} } . Parasitology International.

Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: A review @article { author = {Gouveia MJ and Brindley, Paul J. and Santos, Lúcio Lara and Correia da Costa, José Manuel and Gomes, Paula and Vale, Nuno}, title = {Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: A review}, journal = {Metabolism}, volume = {62}, number = {9}, pages = {1206--1217}, year = {2013}, month = {sep}, url = {http://dx.doi.org/10.1016/j.metabol.2013.04.003}, doi = {10.1016/j.metabol.2013.04.003} } . Metabolism.

Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: An oestrogen–DNA adducts mediated pathway? @article { author = {Botelho, Mónica C. and Vale, Nuno and Gouveia MJ and Rinaldi, Gabriel and Santos, Julio and Santos, Lucio L. and Gomes, Paula and Brindley, Paul J. and Correia da Costa, José Manuel}, title = {Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: An oestrogen–DNA adducts mediated pathway?}, journal = {International Journal for Parasitology}, volume = {43}, number = {1}, pages = {17--26}, year = {2013}, month = {jan}, url = {http://dx.doi.org/10.1016/j.ijpara.2012.10.023}, doi = {10.1016/j.ijpara.2012.10.023} } . International Journal for Parasitology.

(2013). Tumor-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: An oestrogen-DNA adducts mediated pathway? 43 (2013) 17-26. International Journal of Parasitology.

WORKING PAPER

PBPK modeling of lamotrigine and efavirenz during pregnancy: implications for personalized dosing and drug-drug interactin management @unpublished { author = {Costa, Bárbara and Gouveia, Maria João and Vale, Nuno and Corresponding author: Vale, Nuno.}, title = {PBPK modeling of lamotrigine and efavirenz during pregnancy: implications for personalized dosing and drug-drug interactin management}, year = {2024}, month = {sep}, url = {https://www.mdpi.com/1999-4923/16/9/1163}, doi = {10.3390/pharmaceutics16091163}, keywords = { pharmacokinetics; pregnancy; PBPK models; lamotrigine (LTG); efavirenz (EFV); drug-drug interactions (DDI); UGT enzymes; therapeutic management} } .