プロフィール詳細

プロジェクトを作成

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Dr. Marisa B.に依頼

United States

PhD Scientist Specializing in Biochemistry, Cellular Biology, Data Analysis, and Scientific Writing

プロフィール概要

I am a PhD-trained scientist with extensive experience in scientific writing, editing, and data analysis. My expertise spans biochemistry, cellular biology, and mitochondrial bioenergetics, and I specialize in helping researchers and clinicians effectively communicate their findings through high-quality manuscripts, proposals, and reports. With a strong technical background, I bring the following skills to my writing and editing services: - Expertise in high-resolution respirometry and fluorometry for mitochondrial and cellular bioenergetics analysis, including assay development and troubleshooting. - Development and optimization of a coenzyme Q (CoQ) redox method using targeted mass spectrometry for isolated mitochondria and tissue. - Proficiency in cell culture techniques, including lentiviral-mediated gene knockdowns, and experience designing experiments to study gene function. - Skilled in mouse dissection and handling, including maintaining genetically modified mouse models for phenotypic characterization. - Advanced data analysis, including statistical analysis, visualization, and interpretation of complex datasets. I have authored and co-authored peer-reviewed publications and have extensive experience editing manuscripts for clarity, accuracy, and scientific rigor.

専門分野

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Cell Biology
• ☆ Cell Signaling Pathways
• ☆ Nutrition Science
• ☆ Cell Culture

サービス

• Research

Research Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

職務経験

University of Utah

- 現在

Graduate Research Assistant / Research Assistant

University of Utah

8月 2019 - 現在

Graduate Reseach and Teaching Assistant

Central Michigan University

8月 2017 - 5月 2019

Dietary Technician

Michigan Medicine

8月 2016 - 5月 2017

学歴

PhD

University of Utah

8月 2019 - 現在

認定資格

• n/a

  n/a

  1月 2025 - 1月 2025

出版物

PREPRINT

Marisa J. Brothwell, Guoshen Cao, J. Alan Maschek, Annelise M. Poss, Alek D. Peterlin, Liping Wang, Talia B. Baker, Justin L. Shahtout, Piyarat Siripoksup, Quentinn J. Pearce, et al. (2024). Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis .

Marisa Brothwell, Ahmad A Cluntun, Joseph R. Visker, Jesse Velasco-Silva, Luis Cedeno-Rosario, Thirupura Sundari Shankar, Rana Hamouche, Jing Ling, Ji Eon Kim, Ashish G. Toshniwal, et al. (2024). Direct mitochondrial import of lactate supports resilient carbohydrate oxidation .

JOURNAL ARTICLE

Piyarat Siripoksup, Guoshen Cao, Ahmad A Cluntun, J. Alan Maschek, Quentinn Pearce, Marisa J. Brothwell, Mi-Young Jeong, Hiroaki Eshima, Patrick J. Ferrara, Precious Opurum, et al. (2024). Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism . Journal of Clinical Investigation.

Naomi M.M.P. de Hart, Jonathan J. Petrocelli, Rebekah J. Nicholson, Elena M. Yee, Lisha van Onselen, Marisa J. Lang, Paul-Emile Bourrant, Patrick J. Ferrara, Eric D. Bastian, Loren S. Ward, et al. (2024). Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in mice fed a high-fat diet . Journal of Dairy Science.

Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, John Alan Maschek, Anthony R P Verkerke, Piyarat Siripoksup, Amandine Chaix, James E Cox, et al. (2023). Weight loss increases skeletal muscle mitochondrial energy efficiency in obese mice . Life Metabolism.

Jonathan J. Petrocelli, Naomi M.M.P. de Hart, Marisa J. Lang, Elena M. Yee, Patrick J. Ferrara, Dennis K. Fix, Amandine Chaix, Katsuhiko Funai, Micah J. Drummond (2023). Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail . Aging.

Jordan M. Johnson, ALEK PETERLIN, Enrique Balderas-Angeles, Elahu Gosney Sustarsic, J. Alan Maschek, Marisa J. Lang, Alejandro Jara-Ramos, Vanja Panic, Jeffrey T. Morgan, Claudio J. Villanueva, et al. (2023). Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis . Science Advances.

David R. Eberhardt, Sandra H. Lee, Xue Yin, Anthony M. Balynas, Emma C. Rekate, Jackie N. Kraiss, Marisa J. Lang, Maureen A. Walsh, Molly E. Streiff, Andrea C. Corbin, et al. (2022). EFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia . Journal of Molecular and Cellular Cardiology.