プロフィール詳細

プロジェクトを作成

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Dr. Marta A.に依頼

Portugal

PhD, MSL, HTA and RWE certified, EUPATI Trainee

プロフィール概要

Scientist with a PhD in Cardiovascular Disease, EUPATI Trainee, certified MSL with knowledge of Digital Health Marketing, Medical Affairs and Real World Evidence. More than 10 years of experience in regenerative medicine and translational research encompassing hiPSC cell models, organoids and 3D models, drug candidate screening for heart failure and cardiotoxicity using high-throughput systems. Proficient in planning, conducting research and mentoring of researchers, physicians and students. Highly dynamic and a team player, passionate about science communication and networking. Driven by a strong motivation to improve healthcare through better networking and communication between patients, physicians, researchers and stakeholders.Scientist with a PhD in Cardiovascular Disease, EUPATI Trainee, certified MSL with knowledge of Digital Health Marketing, Medical Affairs and Real World Evidence. More than 10 years of experience in regenerative medicine and translational research encompassing hiPSC cell models, organoids and 3D models, drug candidate screening for heart failure and cardiotoxicity using high-throughput systems. Proficient in planning, conducting research and mentoring of researchers, physicians and students. Highly dynamic and a team player, passionate about science communication and networking. Driven by a strong motivation to improve healthcare through better networking and communication between patients, physicians, researchers and stakeholders.

専門分野

• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Banking
• ☆ 3D Cell Culture
• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Phenotypic Assays
• ☆ Precision Medicine
• ☆ Health Technology Assessment
• ☆ Healthcare Administration & Management
• ☆ Medical Affairs
• ☆ Peer Review
• ☆ Fact Checking
• ☆ Literature Search
• ☆ Skills Training
• ☆ Healthcare Communications
• ☆ Patient Education Materials
• ☆ Research Summaries & Abstracts
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ SOP & Protocol Writing
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Language Translation

サービス

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

職務経験

Postdoctoral Fellow

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica

10月 2017 - 現在

Postdoctoral Associate

Imperial College London

3月 2014 - 9月 2017

Research Technician

Imperial College London

1月 2011 - 2月 2014

Research assistant

University College London

1月 2010 - 10月 2010

学歴

PhD Cellular Biology (Biology)

Universidade de Coimbra Faculdade de Ciencias e Tecnologia

1月 2006 - 10月 2011

MSC Biochemistry (Faculty of Science and Technology)

University of Coimbra

9月 2000 - 7月 2005

認定資格

• Certificado de Competências Pedagógicas

  iEFP

  4月 2022 - 現在

• Medical Science Liaison

  Universidade Católica de Lisboa, Portugal

  9月 2020 - 現在

出版物

JOURNAL ARTICLE

Ana F. Louro, Marta A. Paiva, Marta R. Oliveira, Katharina A. Kasper, Paula M. Alves, Patrícia Gomes‐Alves, Margarida Serra (2022). Bioactivity and miRNome Profiling of Native Extracellular Vesicles in Human Induced Pluripotent Stem Cell‐Cardiomyocyte Differentiation . Advanced Science.

Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Faust D, Jarvis A, et al.(2019). MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo . Cell stem cell.

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. @article { author = {Fiedler LR and Chapman K and Xie M and Maifoshie E and Jenkins M and Golforoush PA and Bellahcene M and et al.}, title = {MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.}, journal = {Cell stem cell}, year = {2019}, month = {mar}, url = {http://europepmc.org/abstract/med/30853557}, doi = {10.1016/j.stem.2019.01.013} } . Cell stem cell.

Adamowicz, Martyna, Morgan, Claire C., Haubner, Bernhard J., Noseda, Michela, Collins, Melissa J., Paiva, Marta Abreu, Srivastava, Prashant K., Gellert, Pascal, Razzaghi, Bonnie, O'Gara, Peter, et al.(2018). Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human . Circulation-Cardiovascular Genetics. 11. (2).

Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human @article { author = {Adamowicz, Martyna and Morgan, Claire C. and Haubner, Bernhard J. and Noseda, Michela and Collins, Melissa J. and Paiva, Marta Abreu and Srivastava, Prashant K. and et al.}, title = {Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human}, journal = {Circulation-Cardiovascular Genetics}, volume = {11}, number = {2}, year = {2018}, url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000426177700003&KeyUID=WOS:000426177700003}, doi = {10.1161/CIRCGEN.117.001805} } . Circulation-Cardiovascular Genetics.

Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment. @article { author = {Paiva, Marta}, title = {Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment.}, journal = {ACS central science}, year = {2017}, month = {apr}, url = {http://europepmc.org/abstract/med/28470052}, doi = {10.1021/acscentsci.7b00039} } . ACS central science.

et al.(2017). Multimodal Hydrogel-Based Platform To Deliver and Monitor Cardiac Progenitor/Stem Cell Engraftment . ACS central science.

et al.(2015). Enhanced efficiency of genetic programming toward cardiomyocyte creation through topographical cues . Biomaterials.

Enhanced efficiency of genetic programming toward cardiomyocyte creation through topographical cues. @article { author = {Paiva, Marta}, title = {Enhanced efficiency of genetic programming toward cardiomyocyte creation through topographical cues.}, journal = {Biomaterials}, year = {2015}, month = {nov}, url = {http://europepmc.org/abstract/med/26302234}, doi = {10.1016/j.biomaterials.2015.07.063} } . Biomaterials.

PDGFRa demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium. @article { author = {Paiva, Marta}, title = {PDGFRa demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium.}, journal = {Nature communications}, year = {2015}, month = {may}, url = {http://europepmc.org/abstract/med/25980517}, doi = {10.1038/ncomms7930} } . Nature communications.

et al.(2015). PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium . Nature communications.

et al.(2015). Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5 . PloS one.

Noseda, M., Abreu-Paiva, M., Schneider, M.D., Noseda, M., Abreu-Paiva, M., Schneider, M.D.(2015). The quest for the adult cardiac stem cell . Circulation Journal. 79. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1422-1430.

Michela Noseda, Marta Abreu-Paiva, Michael D. Schneider(2015). The Quest for the Adult Cardiac Stem Cell . Circulation Journal. 79. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1422--1430. Japanese Circulation Society

Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5. @article { author = {Paiva, Marta}, title = {Forward Programming of Cardiac Stem Cells by Homogeneous Transduction with MYOCD plus TBX5.}, journal = {PloS one}, year = {2015}, url = {http://europepmc.org/abstract/med/26047103}, doi = {10.1371/journal.pone.0125384} } . PloS one.

The quest for the adult cardiac stem cell @article { author = {Noseda, M. and Abreu-Paiva, M. and Schneider, M.D. and Michela Noseda and Marta Abreu-Paiva and Michael D. Schneider}, title = {The quest for the adult cardiac stem cell}, journal = {Circulation Journal}, volume = {79}, number = {7}, pages = {1422--1430}, year = {2015}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-84934268195&partnerID=MN8TOARS}, doi = {10.1253/circj.CJ-15-0557; 10.1253/circj.cj-15-0557} } . Circulation Journal.

PDGFRalpha demarcates the cardiogenic and clonogenic Sca-1+stem cell @article { author = {Noseda, M. and Harada, M. and Mcsweeney, S. and Leja, T. and Belian, E. and Macaulay, I. and Paiva, M. Abreu and et al.}, title = {PDGFRalpha demarcates the cardiogenic and clonogenic Sca-1+stem cell}, journal = {Cardiovascular Research}, volume = {103}, year = {2014}, url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000343730100460&KeyUID=WOS:000343730100460}, doi = {10.1093/cvr/cvu098.25} } . Cardiovascular Research.

Noseda, M., Harada, M., Mcsweeney, S., Leja, T., Belian, E., Macaulay, I., Paiva, M. Abreu, Jacobsen, S. E., Barahona, M., Schneider, M. D., et al.(2014). PDGFRalpha demarcates the cardiogenic and clonogenic Sca-1+stem cell . Cardiovascular Research. 103.

Belian, Elisa, Noseda, Michela, Leja, Thomas, Harada, Mutsuo, Lumbers, Richard T., Paiva, Marta S. Abreu, East, Nick, Sampson, Robert, Schneider, Michael D., Belian, Elisa, et al.(2012). Is Myocardin a limiting factor for cardiac programming? . Circulation Research. 111. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E386.

Is Myocardin a limiting factor for cardiac programming? @article { author = {Belian, Elisa and Noseda, Michela and Leja, Thomas and Harada, Mutsuo and Lumbers, Richard T. and Paiva, Marta S. Abreu and East, Nick and Sampson, Robert and Schneider, Michael D.}, title = {Is Myocardin a limiting factor for cardiac programming?}, journal = {Circulation Research}, volume = {111}, number = {12}, pages = {E386--E386}, year = {2012}, url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311994700030&KeyUID=WOS:000311994700030} } . Circulation Research.

Noseda, Michela, De Smith, Adam J., Leia, Thomas, Rao, Pulivarthi H., Noseda, Michela, Paiva, Marta S. Abreu, De Smith, Adam J., Al-Beidh, Farah, Leia, Thomas, Blakemore, Alex I., et al.(2012). The Cdkn2a/2b Tumour Suppressor Locus is a Hot Spot for Genome Instability in Mouse Cardiac Progenitor Cells . Circulation. 126. (21).

The Cdkn2a/2b Tumour Suppressor Locus is a Hot Spot for Genome Instability in Mouse Cardiac Progenitor Cells @article { author = {Noseda, Michela and De Smith, Adam J. and Leia, Thomas and Rao, Pulivarthi H. and Paiva, Marta S. Abreu and Al-Beidh, Farah and Blakemore, Alex I. and Schneider, Michael D.}, title = {The Cdkn2a/2b Tumour Suppressor Locus is a Hot Spot for Genome Instability in Mouse Cardiac Progenitor Cells}, journal = {Circulation}, volume = {126}, number = {21}, year = {2012}, url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208885008239&KeyUID=WOS:000208885008239} } . Circulation.

et al.(2011). Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury . American Journal of Physiology - Heart and Circulatory Physiology.

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury. @article { author = {Paiva, Marta}, title = {Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury.}, journal = {American Journal of Physiology - Heart and Circulatory Physiology}, year = {2011}, month = {jun}, url = {http://europepmc.org/abstract/med/21421816}, doi = {10.1152/ajpheart.00707.2010} } . American Journal of Physiology - Heart and Circulatory Physiology.

et al.(2010). Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction . Cardiovascular drugs and therapy.

Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction. @article { author = {Paiva, Marta}, title = {Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.}, journal = {Cardiovascular drugs and therapy}, year = {2010}, month = {feb}, url = {http://europepmc.org/abstract/med/20229055}, doi = {10.1007/s10557-010-6222-3} } . Cardiovascular drugs and therapy.

et al.(2009). Metformin prevents myocardial reperfusion injury by activating the adenosine receptor . Journal of cardiovascular pharmacology.

et al.(2009). Metformin prevents myocardial reperfusion injury by activating the adenosine receptor . Journal of cardiovascular pharmacology.

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor @article { author = {Paiva, M. and Riksen, N.P. and Davidson, S.M. and Hausenloy, D.J. and Monteiro, P. and Gonçalves, L. and Providência, L. and et al.}, title = {Metformin prevents myocardial reperfusion injury by activating the adenosine receptor}, journal = {Journal of Cardiovascular Pharmacology}, volume = {53}, number = {5}, pages = {373--378}, year = {2009}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-67650921900&partnerID=MN8TOARS}, doi = {10.1097/FJC.0b013e31819fd4e7; 10.1097/fjc.0b013e31819fd4e7} } . Journal of Cardiovascular Pharmacology.

Paiva, M., Riksen, N.P., Davidson, S.M., Hausenloy, D.J., Monteiro, P., Gonçalves, L., Providência, L., Rongen, G.A., Smits, P., Mocanu, M.M., et al.(2009). Metformin prevents myocardial reperfusion injury by activating the adenosine receptor . Journal of Cardiovascular Pharmacology. 53. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 373-378.

et al.(2008). Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening . Basic research in cardiology.

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening. @article { author = {Paiva, Marta}, title = {Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening.}, journal = {Basic research in cardiology}, year = {2008}, month = {may}, url = {http://europepmc.org/abstract/med/18080084}, doi = {10.1007/s00395-007-0691-y} } . Basic research in cardiology.

Monteiro, Pedro, Paiva, M., Monteiro, Pedro, Paiva, M., Carreira, R., Carreira, R., Duarte, A., Duarte, A., Providencia, L., Providencia, L.(2007). Effect of chronic insulin therapy on mitochondrial function in an ex vivo animal model of diabetes and hypercaloric diet submitted to global myocardial ischemia-reperfusion . Circulation Research. 101. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString E71.

Monteiro, P. F., Matafome, P., Paiva, M., Carreira, R., Seica, R., Goncalves, L., Providencia, L. A., Monteiro, P. F., Matafome, P., Paiva, M., et al.(2007). Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of diabetes and hypercaloric diet submitted to global myocardial ischemia-reperfusion . European Heart Journal. 28. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 438.

Monteiro, P. F., Paiva, M., Carreira, R., Duarte, A. I., Goncalves, L. M., Providencia, L. A., Monteiro, P. F., Paiva, M., Carreira, R., Duarte, A. I., et al.(2006). Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion . European Heart Journal. 27. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 527.

Monteiro, P. F., Paiva, M., Carreira, R., Duarte, A. I., Goncalves, L. M., Providencia, L. A., Monteiro, P. F., Paiva, M., Carreira, R., Duarte, A. I., et al.(2006). Effect of chronic metformin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion . European Heart Journal. 27. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 408-409.

Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion @article { author = {Monteiro, P. F. and Paiva, M. and Carreira, R. and Duarte, A. I. and Goncalves, L. M. and Providencia, L. A. and Monteiro, Pedro and et al.}, title = {Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion}, journal = {European Heart Journal}, volume = {27}, number = {5}, pages = {527--527}, year = {2006}, url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000240668403436&KeyUID=WOS:000240668403436} } . European Heart Journal.

(2005). Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology.

Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia. @article { author = {Paiva, Marta}, title = {Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia.}, journal = {Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology}, year = {2005}, month = {nov}, url = {http://europepmc.org/abstract/med/16463987} } . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology.

Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia | Impacto da isquemia-reperfusão aguda na função mitocondrial num modelo animal ex-vivo de isquemia global @article { author = {Paiva, M.A. and Carreira, R. and Monteiro, P. and Gonçalves, L.M. and Providência, L.A.}, title = {Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia | Impacto da isquemia-reperfusão aguda na função mitocondrial num modelo animal ex-vivo de isquemia global}, journal = {Revista Portuguesa de Cardiologia}, volume = {24}, number = {11}, pages = {1381--1392}, year = {2005}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-30944444776&partnerID=MN8TOARS} } . Revista Portuguesa de Cardiologia.

Paiva, M.A., Carreira, R., Monteiro, P., Gonçalves, L.M., Providência, L.A., Paiva, M.A., Carreira, R., Monteiro, P., Gonçalves, L.M., Providência, L.A.(2005). Impact of acute ischemia-reperfusion on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia | Impacto da isquemia-reperfusão aguda na função mitocondrial num modelo animal ex-vivo de isquemia global . Revista Portuguesa de Cardiologia. 24. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1381-1392.