プロフィール詳細

プロジェクトを作成

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Dr. Marta S.に依頼

Portugal

PhD Scientific Writer & Editor | Manuscripts, Grants, Literature Reviews

プロフィール概要

I am a PhD-trained researcher in Molecular and Cell Biology from the University of Porto, with a strong focus on immunology and infectious diseases, particularly tuberculosis. During my doctoral work, I explored host–pathogen interactions with the goal of identifying novel therapeutic and diagnostic strategies to improve disease management and patient outcomes. I hold an MSc in Applied Microbiology from the Faculty of Sciences of the University of Lisbon (2019), where I worked on the development of immunoliposome-based approaches for the treatment of pneumococcal meningitis, in collaboration with the Faculty of Veterinary Medicine. I completed my BSc in Biochemistry at the University of Porto (2017), where I gained early research experience in protein cloning, expression, and purification, focusing on the MAPK Cek1 from Candida albicans. Following my MSc, I worked as a Molecular Biology Scientist at Vector B2B – Drug Development Services, where I contributed to the development and optimization of in vitro models and supported early-stage drug discovery projects across oncology and infectious diseases. Overall, my work has given me a strong foundation in experimental research, scientific writing, and data interpretation. I am particularly interested in bridging rigorous science with clear communication and translational impact.

専門分野

• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Industrial Microbiology
• ☆ Microbiological Assays
• ☆ Biochemistry
• ☆ Apoptosis
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ PCR
• ☆ Cell Biology
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Pathogenesis
• ☆ Clinical Microbiology

サービス

• Writing
• Research
• Consulting

Writing Medical Writing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

職務経験

Junior Researcher

I3s- Instituto de Investigação e Inovação em Saúde

10月 2025 - 現在

Molecular Biology Scientist

Co-Lab Vector B2B

11月 2019 - 11月 2020

学歴

PhD in Cell and Molecular Biology (ICBAS)

Universidade do Porto

1月 2021 - 7月 2025

Msc in Applied Microbiology

Universidade de Lisboa Faculdade de Ciências

4月 2017 - 11月 2019

Bsc in Biochemistry

Universidade do Porto Faculdade de Ciências

9月 2014 - 6月 2017

認定資格

• Research Project Management

  I3s - Instituto de Investigação e Inovação em Saúde

  7月 2025 - 現在

• Becoming a Medical Writer

  W4Research

  5月 2025 - 現在

• Tranlational Medicine Explained

  EATRIS

  10月 2024 - 現在

• FELASA C

  i3s- Instituto de Investigação e Inovação em Saúde

  5月 2023 - 現在

出版物

CONFERENCE POSTER

Immunoinformatics predictions on Mycobacterium tuberculosis Lineage-specific T cell epitopes and HLA Class I/II interactions in West Africa @misc { author = {Silva, Marta}, title = {Immunoinformatics predictions on Mycobacterium tuberculosis Lineage-specific T cell epitopes and HLA Class I/II interactions in West Africa }, year = {2025}, month = {feb} }. 11th McBiology.

Timely activation of the LXR is a promising Host-Directed Therapy for Tuberculosis”. @misc { author = {Silva, Marta and Couto, J and Rute Gonçalves}, title = {Timely activation of the LXR is a promising Host-Directed Therapy for Tuberculosis”.}, year = {2024}, month = {mar} }. Tuberculosis: The Host-Pathogen Interface conference, Keystone, Colorado.

Whole blood transcriptional analysis of M.tuberculosis vs M.africanum infected patients reveals the nuclear receptor pathway as a potential disease severity marker.” @misc { author = {Silva, Marta and Couto, J}, title = {Whole blood transcriptional analysis of M.tuberculosis vs M.africanum infected patients reveals the nuclear receptor pathway as a potential disease severity marker.”}, year = {2023}, month = {mar} }. XLVIII Annual Meeting of the Portuguese Society for Immunology.

Host-pathogen interactions in tuberculosis: the immune response to Mycobacterium africanum during infection @misc { author = {Silva, Marta and Couto, J}, title = {Host-pathogen interactions in tuberculosis: the immune response to Mycobacterium africanum during infection}, year = {2022}, month = {oct} }. 5th PhDay i3s.

“Host-pathogen interactions in tuberculosis: the immune response to Mycobacterium africanum during infection” @misc { author = {Silva, Marta}, title = {“Host-pathogen interactions in tuberculosis: the immune response to Mycobacterium africanum during infection”}, year = {2022}, month = {sep} }. EMBO Workshop on Tuberculosis 2022: From innovation to intervention.

Mycobacterium africanum and Mycobacterium tuberculosis induce differential immune responses during tuberculosis”. @misc { author = {Silva, Marta}, title = {Mycobacterium africanum and Mycobacterium tuberculosis induce differential immune responses during tuberculosis”.}, year = {2022}, month = {apr} }. Sociedade Portuguesa de Imunologia 47th annual meeting.

Overcoming the BBB: in vivo selection of single domain antibodies for brain targeting and drug delivery @misc { author = {Aguiar, Sandra I and Silva, Marta (601E-6149-5DAD) (poster presenter) and Martins, Diana and André, Ana S and Neves, Vera and Dias, Joana NR and et al.}, title = {Overcoming the BBB: in vivo selection of single domain antibodies for brain targeting and drug delivery }, year = {2019}, month = {nov} }. 11th Annual PEGS EUROPE 18-22th November 2019, Lisbon, Portugal.

JOURNAL ARTICLE

SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice @article { author = {Gonçalves, Rute and Couto, Joana and Ferreirinha, Pedro and Costa, José Maria and Silvério, Diogo and Silva, Marta and Fernandes, Ana Isabel and et al.}, title = {SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice}, journal = {iScience}, volume = {26}, number = {2}, pages = {105972}, year = {2023}, month = {feb}, url = {https://doi.org/10.1016/j.isci.2023.105972}, doi = {10.1016/j.isci.2023.105972} } . iScience.

Gonçalves, R., Couto, J., Ferreirinha, P., Costa, J.M., Silvério, D., Silva, M.L., Fernandes, A.I., Madureira, P., Alves, N.L., Lamas, S., et al.(2023). SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice . iScience. 26. (2).

Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns @article { author = {Silva, Marta L. and Cá, Baltazar and Osório, Nuno S. and Rodrigues, Pedro N. S. and Maceiras, Ana Raquel and Saraiva, Margarida}, title = {Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns}, journal = {PLOS Pathogens}, volume = {18}, number = {5}, pages = {e1010490}, year = {2022}, month = {may}, url = {http://dx.doi.org/10.1371/journal.ppat.1010490}, doi = {10.1371/journal.ppat.1010490} } . PLOS Pathogens.

Silva, M.L., Cá, B., Osório, N.S., Rodrigues, P.N.S., Maceiras, A.R., Saraiva, M.(2022). Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns . PLoS Pathogens. 18. (5).

Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening @article { author = {Aguiar, Sandra Isabel and Dias, Joana N. R. and André, Ana Santos and Silva, Marta Lisete and Martins, Diana and Carrapiço, Belmira and Castanho, Miguel and et al.}, title = {Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening}, journal = {Pharmaceutics}, volume = {13}, number = {10}, pages = {1598}, year = {2021}, month = {oct}, url = {http://dx.doi.org/10.3390/pharmaceutics13101598}, doi = {10.3390/pharmaceutics13101598} } . Pharmaceutics.

Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance @article { author = {Ferreira, Magda and Ogren, Maria and Dias, Joana N. R. and Silva, Marta and Gil, Solange and Tavares, Luís and Aires-da-Silva, Frederico and Gaspar, Maria Manuela and Aguiar, Sandra Isabel}, title = {Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance}, journal = {Molecules}, volume = {26}, number = {7}, pages = {2047}, year = {2021}, month = {apr}, url = {http://dx.doi.org/10.3390/molecules26072047}, doi = {10.3390/molecules26072047} } . Molecules.

Marta Silva, Magda Ferreira, Maria Ogren, Joana N. R. Dias, Solange Gil, Luís Tavares, Frederico Aires-da-Silva, Maria Manuela Gaspar, Sandra Isabel Aguiar(2021). Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance . Molecules. 26. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2047. {MDPI} {AG}

Marta Silva, Magda Ferreira, Maria Ogren, Joana N. R. Dias, Solange Gil, Luís Tavares, Frederico Aires-da-Silva, Maria Manuela Gaspar, Sandra Isabel Aguiar (2021). Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance . Molecules.

Aguiar, S.I., Dias, J.N.R., André, A.S., Silva, M.L., Martins, D., Carrapiço, B., Castanho, M., Carriço, J., Cavaco, M., Gaspar, M.M., et al.(2021). Highly specific blood-brain barrier transmigrating single-domain antibodies selected by an in vivo phage display screening . Pharmaceutics. 13. (10).

Ferreira, M., Ogren, M., Dias, J.N.R., Silva, M., Gil, S., Tavares, L., Aires-Da-silva, F., Gaspar, M.M., Aguiar, S.I.(2021). Liposomes as antibiotic delivery systems: A promising nanotechnological strategy against antimicrobial resistance . Molecules. 26. (7).

DISSERTATION THESIS

Development of a new immunoliposome for the treatment of pneumococcal meningitis @phdthesis { author = {Silva, Marta}, title = {Development of a new immunoliposome for the treatment of pneumococcal meningitis}, year = {2019}, month = {oct}, url = { http://hdl.handle.net/10451/40166}, school = {Universidade de Lisboa Faculdade de Ciências; Universidade de Lisboa Faculdade de Medicina Veterinária} } . Universidade de Lisboa Faculdade de Ciências; Universidade de Lisboa Faculdade de Medicina Veterinária.

Cloning, expression and purification of Cek1, a polyglutamine-containing MAPK, from the fungal pathogen Candida albicans for functional and structural analysis @phdthesis { author = {Silva, Marta}, title = {Cloning, expression and purification of Cek1, a polyglutamine-containing MAPK, from the fungal pathogen Candida albicans for functional and structural analysis }, year = {2017}, month = {jun}, school = {Universidade do Porto Instituto de Investigação e Inovação em Saúde; Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar; Universidade do Porto Faculdade de Ciências} }. Universidade do Porto Instituto de Investigação e Inovação em Saúde; Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar; Universidade do Porto Faculdade de Ciências.