プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

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☆☆☆☆☆

Dr. Mathias R.に依頼

United States

Biotech Advisor | De-Risking Protein Therapeutics (Antibodies, ADCs, Bispecifics) | CMC & Early-Stage Strategy

プロフィール概要

I help biotech teams de-risk and accelerate protein therapeutics programs, from early discovery to IND. I am a PhD-level protein scientist and former Director of Protein Sciences with 10+ years of industry experience across startups and Big Pharma. I have built three protein biochemistry labs from the ground up and supported multiple programs advancing into IND-enabling studies. My core expertise is in antibody-based therapeutics, including monoclonal antibodies, bispecifics, antibody-drug conjugates (ADCs), and fusion proteins. I specialize in solving complex expression, purification, and developability challenges that delay programs and increase cost. What I can help you with: • Antibody & protein therapeutic development strategy (discovery → IND) • Developability assessments (stability, aggregation, viscosity, manufacturability) • Expression & purification troubleshooting (mammalian and microbial systems) • Analytical method strategy (SEC, IEX, HIC, MS, binding assays) • CMC and IND-enabling planning • CRO/CDMO selection, oversight, and tech transfer • Technical due diligence for investors and BD teams Selected impact: • Designed purification workflows improving bispecific antibody purity to >95% while reducing timelines • Built and scaled protein science infrastructure at multiple startups • Supported IND-enabling workstreams and CDMO selection for clinical-stage programs • Inventor on multiple patents and author of 20+ peer-reviewed publications (Science, Nature Immunology) I work best with: • Early-stage biotech companies needing hands-on problem-solving • Teams preparing for IND or scaling CMC activities • Investors seeking rigorous technical due diligence

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Binding Assays
• ☆ Biophysics
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression

サービス

• Writing
• Research
• Consulting
• Product Development

Writing General Proofreading & Editing, Translation

Research User Research, Technology Scouting, Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Product Development Formulation

職務経験

Director, Protein Sciences and Analytics

Rondo Therapeutics

4月 2023 - 11月 2024

学歴

PhD

University of Heidelberg, Germany

1月 1994 - 11月 2000

認定資格

• 認定資格の詳細は未入力です。