プロフィール詳細

プロジェクトを作成

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Dr. McLane M.に依頼

United States

PhD Biomedical Scientist - Metabolism & Mitochondrial Biology - Data Analysis, Experimental Design, Scientific Writing

プロフィール概要

I am a PhD-trained biomedical scientist and current postdoctoral associate researcher at the University of Georgia with a strong foundation in cellular metabolism, mitochondrial biology, and translational research. My work spans academic and applied science, allowing me to support clients across experimental design, data analysis, and scientific communication. During my PhD, I investigated how alterations in mitochondrial Complex I influence colorectal cancer (CRC) growth and progression. This work involved dissecting mitochondrial dysfunction, metabolic reprogramming, and their downstream effects on tumor development, providing me with deep expertise in bioenergetics, cancer metabolism, and mechanistic biology. Additionally, this work has led to the publication of 14 peer-reviewed scientific publications, including publications in the journals Molecular Metabolism, Cancer Metabolism and Scientific Advances. In my current postdoctoral research, I focus on mitochondrial function in response to volumetric muscle loss, integrating physiology with cellular and molecular approaches to understand tissue remodeling and recovery. In parallel, I utilize advanced 3D liver organoid models to evaluate drug delivery, therapeutic efficacy, and the impact of diet on liver health, bridging in vitro modeling with translational and clinically relevant outcomes. I bring a broad and versatile skill set that includes experimental design, mitochondrial and metabolic assays, enzyme kinetics, data interpretation, and scientific writing. I am particularly experienced in translating complex biological questions into actionable research strategies and clear, high-quality deliverables. I am available for consulting on biomedical research projects, including study design, data analysis, literature review, and scientific writing. Whether you are developing a new project, troubleshooting experiments, or preparing manuscripts or grant applications, I provide rigorous, detail-oriented support tailored to your goals

専門分野

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ PCR
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ RNA Sequencing
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Comparative Physiology
• ☆ Data Analysis
• ☆ Image Processing
• ☆ Data Processing
• ☆ Data Exploration
• ☆ Data Visualization
• ☆ Data Collection
• ☆ Data Management
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Large Scale Cell Culture
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Cytometry
• ☆ Exercise & Fitness
• ☆ Physical Fitness
• ☆ Personal Training
• ☆ Men's Interest
• ☆ Clinical Trials
• ☆ IRB Applications
• ☆ Clinical Trial Design
• ☆ Patient Recruitment
• ☆ Clinical Data Management
• ☆ Clinical Trials Data Analysis
• ☆ Human Biology
• ☆ Kinesiology & Exercise Science

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Creative Writing, Audio Transcription, General Proofreading & Editing

Research Systematic Literature Review

Consulting Digital Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Data Processing

職務経験

Postdoctoral Associate

University of Georgia

2月 2026 - 5月 2029

PhD Candidate

East Carolina University

8月 2020 - 12月 2025

学歴

PhD Biomedical Sciences

East Carolina University

8月 2021 - 12月 2025

Master's (Exercise Physiology )

Florida State University

8月 2019 - 5月 2021

Bachelor's (Kinesiology )

Georgia College & State University

8月 2014 - 5月 2019

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

James T. Hagen, McLane M. Montgomery, Raphael T. Aruleba, Brett R. Chrest, Polina Krassovskaia, Thomas D. Green, Emely A. Pacheco, Miki Kassai, Tonya N. Zeczycki, Cameron A. Schmidt, et al. (2025). Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy . Science Advances.

Tonya Zeczycki, Aaron Schimmer, Cameron Schmidt, Charles Edward Chalfant, Mark David Minden, Thomas Loughran, David J Feith, Kelsey H Fisher-Wellman, James Hagen, Mclane Montgomery, et al. (2025). Acute myeloid leukemia mitochondria hydrolyze ATP to support oxidative metabolism and resist chemotherapy . Science Advances.

Manuella R. Andrade, Tooyib A. Azeez, McLane M. Montgomery, Jacob T. Caldwell, Hyerim Park, Andy T. Kwok, Alexander M. Borg, S. Anand Narayanan, Jeffrey S. Willey, Michael D. Delp, et al. (2023). Neurovascular dysfunction associated with erectile dysfunction persists after long‐term recovery from simulations of weightlessness and deep space irradiation . The FASEB Journal.

McLane Montgomery, Hagen JT, Montgomery MM, Biagioni EM, Krassovskaia P, Jevtovic F, Shookster D, Sharma U, Tung K, Broskey NT, et al. (2022). Intrinsic adaptations in OXPHOS power output and reduced tumorigenicity characterize doxorubicin resistant ovarian cancer cells . Biochimica et biophysica acta. Bioenergetics.

McLaughlin KL, McLane Montgomery, Nelson MAM, Coalson HS, Hagen JT, Montgomery MM, Wooten AR, Zeczycki TN, Vohra NA, Fisher-Wellman KH (2022). Bioenergetic Phenotyping of DEN-Induced Hepatocellular Carcinoma Reveals a Link Between Adenylate Kinase Isoform Expression and Reduced Complex I-Supported Respiration . Frontiers in oncology.