プロフィール詳細

プロジェクトを作成

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Dr. Michael D.に依頼

United States

Ph. D. Medicinal Chemist | CNS Drug Discovery | Leading Innovative Research in Neurological Disorders

プロフィール概要

Passionate Medicinal Chemist with a strong background in organic chemistry and drug discovery. Proficient in designing, synthesizing, and optimizing small molecules for therapeutic applications. Experienced in hit identification, lead optimization, and structure-activity relationship (SAR) analysis. Adept at analytical techniques including spectroscopy, chromatography, and mass spectrometry for compound characterization. Proven track record of contributing to successful drug discovery programs and collaborating effectively with multidisciplinary teams. Committed to advancing science and improving human health through innovative research and development. Open to exciting opportunities in pharmaceutical research, biotechnology, or academia where I can leverage my skills to drive impactful discoveries and bring new therapies to market. “There is so much more to be done; the patients are waiting.” Dr. Paul Janssen

専門分野

• ☆ Chemical Reagent Development
• ☆ Dewatering & Drying Technology
• ☆ Inorganic Chemistry
• ☆ Physical Chemistry
• ☆ Radiochemistry
• ☆ Organometallic Chemistry
• ☆ Peptide Synthesis
• ☆ Data Collection
• ☆ Nutrition Science
• ☆ Food Microbiology
• ☆ Food Preservation
• ☆ Flavor & Fragrance Chemistry
• ☆ Food Chemistry
• ☆ Nutritional Analysis
• ☆ Data Storage
• ☆ Exercise & Fitness
• ☆ Physical Fitness
• ☆ Athletic Training & Coaching
• ☆ Personal Training
• ☆ Men's Interest
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Medicinal Chemistry
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Drug Formulation
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Drug Substance Characterization
• ☆ Biosafety Testing
• ☆ Bioanalytical Testing
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Bioavailability
• ☆ Human Biology
• ☆ Psychoactive Drugs

サービス

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing

Research Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Product Development Formulation, Stability/Shelf Life Testing, Product Evaluation, Product Validation, Quality Assurance & Control (QA/QC), Product Compliance

職務経験

Senior Researcher

Saint Joseph's University

- 現在

Laboratory Manager

Saint Joseph's University

6月 2022 - 6月 2024

Laboratory Manager

University of the Sciences

8月 2021 - 6月 2022

Researcher

University of the Sciences

3月 2021 - 8月 2021

Laboratory Technician

University of the Sciences

8月 2020 - 3月 2021

学歴

Doctor of Philosophy (PhD) (Chemistry and Biochemistry)

Saint Joseph's University

6月 2022 - 5月 2023

Doctor of Philosophy (PhD) (Chemistry and Biochemistry)

University of the Sciences

1月 2015 - 6月 2022

Bachelor of Sciences (Chemistry and Biochemistry)

University of the Sciences

8月 2010 - 5月 2014

認定資格

• American Chemical Certification

  ACS

  4月 2014 - 現在

出版物

DISSERTATION THESIS

Michael Dybek (2023). Structure Activity Relationship (SAR) Studies of 1,2-Diarylethylamines as N-Methyl-D-Aspartate Receptor Antagonists . Structure Activity Relationship (SAR) Studies of 1,2-Diarylethylamines as N-Methyl-D-Aspartate Receptor Antagonists.

JOURNAL ARTICLE

Famojuro TI, Elufioye TO, Olajide OA, Dybek M, Adejare A (2021). New cytotoxic compounds from the leaves of <i>Caesalpinia</i> <i>benthamiana</i> (Baill.) Herend. & Zarucchi (Fabaceae) . Avicenna journal of phytomedicine.

A. D. Ladagu, F. E. Olopade, O. R. Folarin, T. O. Elufioye, J. V. Wallach, M. B. Dybek, James Olopade, A. Adejare (2020). Novel NMDA-receptor antagonists ameliorate vanadium neurotoxicity . Naunyn-Schmiedeberg's Archives of Pharmacology.

Michael Dybek, Jason Wallach, Tristan Colestock, Juli&#224; Agramunt, Matt D.B. Claydon, Nadine Filemban, Muhammad Chatha, Adam L. Halberstadt, Simon D. Brandt, David Lodge, et al. (2019). Pharmacological characterizations of the 'legal high' fluorolintane and isomers . European Journal of Pharmacology.

Michael Dybek, Jason Wallach, Pierce Kavanagh, Tristan Colestock, Nadine Filemban, Dr. Geraldine Dowling, Folker Westphal, Simon Elliott, Adeboye Adejare, Simon D. Brandt (2019). Syntheses and analytical characterizations of the research chemical 1‐[1‐(2‐fluorophenyl)‐2‐phenylethyl]pyrrolidine (fluorolintane) and five of its isomers . Drug Testing and Analysis.

BOOK CHAPTER

Michael Dybek, Anush Abelian, Jason Wallach, Boyenoh Gaye, Adeboye Adejare (2021). Pharmaceutical chemistry . Remington.

PATENT

Michael Dybek Fluorinated Tryptamine Compounds, Analogues Thereof, and Methods Using Same .