プロフィール詳細

プロジェクトを作成

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Dr. Michele C.に依頼

Italy

More than 10 years experience in cancer research in international settings, grants and articles writing and editing

プロフィール概要

Over the past 10 years, I have successfully been working in the oncology field, having the opportunity to work with high-quality and well-recognized research groups. My research has been focused on the discovery of new molecular targets in pancreatic, renal, ovarian and prostate cancer and metastasis, in order to develop effective combinational treatments and improve the clinical outcome with a special focus on preclinical models, that can be used for personalized medicine. My experience in an international clinical research setting, where I work among medical doctors and scientists from different countries, has afforded me the opportunity to enhance my written/verbal communication skills, interpersonal skills, build critical business relationships, and strengthen and continuously improve upon my analytical, problem-solving, time management and teamwork skills.

専門分野

• ☆ Animal Genetics
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Stem Cell Research
• ☆ Biotechnology & Bioengineering
• ☆ Oncology
• ☆ Immunotherapy
• ☆ Cancer Research
• ☆ Manuscript & Journal Article Writing

サービス

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Technical Writing

Research Market Research, Feasibility Study

Consulting Scientific and Technical Consulting

職務経験

Weill Cornell Medical College

9月 2016 - 現在

Institut d'Investigacions Biomèdiques August Pi i Sunyer

1月 2016 - 8月 2016

Postdoctoral

Centro Nacional de Investigaciones Oncológicas

7月 2014 - 12月 2014

PhD Student

Centro Nacional de Investigaciones Oncológicas

9月 2009 - 6月 2014

Internship

Istituto Nazionale Tumori IRCCS Fondazione Pascale

1月 2007 - 7月 2009

学歴

Molecular Biology, Biotechnology and Biochemistry

Universidad Autonoma de Madrid Facultad de Ciencias

9月 2009 - 6月 2014

Medical Biotechnology

Universita degli Studi di Napoli Federico II

1月 2007 - 3月 2009

Biotechnology

Universita degli Studi di Napoli Federico II

10月 2003 - 12月 2006

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Hoshino A, Kim HS, Bojmar L, Gyan KE, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S, et al.(2020). Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers . Cell.

(2020). A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids . Cell stem cell.

Cioffi M, Trabulo SM, Vallespinos M, Raj D, Kheir TB, Lin ML, Begum J, Baker AM, Amgheib A, Saif J, Perez M, Soriano J, Desco M, Gomez-Gaviro MV, Cusso L, Megias D, Aicher A, Heeschen C, Oncotarget, 2017, vol. 8, no. 13, pp. 21609-21625, 2017 .

Cioffi, M., Trabulo, S.M., Vallespinos, M., Raj, D., Kheir, T.B., Lin, M.-L., Begum, J., Baker, A.-M., Amgheib, A., Saif, J., et al.(2017). The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1 . Oncotarget. 8. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 21609-21625.

Cioffi M, Vallespinos-Serrano M, Trabulo SM, Fernandez-Marcos PJ, Firment AN, Vazquez BN, Vieira CR, Mulero F, Camara JA, Cronin UP, Perez M, Soriano J, G Galvez B, Castells-Garcia A, Haage V, Raj D, Megias D, Hahn S, Serrano L, Moon A, Cell reports, 2015, vol. 12, no. 10, pp. 1594-1605, 2015 .

Cioffi M, Trabulo S, Hidalgo M, Costello E, Greenhalf W, Erkan M, Kleeff J, Sainz B Jr, Heeschen C, Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, vol. 21, no. 10, pp. 2325-2337 .

Sainz B Jr, Alcala S, Garcia E, Sanchez-Ripoll Y, Azevedo MM, Cioffi M, Tatari M, Miranda-Lorenzo I, Hidalgo M, Gomez-Lopez G, Cañamero M, Erkan M, Kleeff J, García-Silva S, Sancho P, Hermann PC, Heeschen C, Gut, 2015 .

Cioffi M, Trabulo SM, Sanchez-Ripoll Y, Miranda-Lorenzo I, Lonardo E, Dorado J, Reis Vieira C, Ramirez JC, Hidalgo M, Aicher A, Hahn S, Sainz B Jr, Heeschen C, Gut, 2015 .

Cioffi, M., Vallespinos-Serrano, M., Trabulo, S.M., Fernandez-Marcos, P.J., Firment, A.N., Vazquez, B.N., Vieira, C.R., Mulero, F., Camara, J.A., Cronin, U.P., et al.(2015). MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3 . Cell Reports. 12. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1594-1605.

Cioffi, M., Trabulo, S.M., Sanchez-Ripoll, Y., Miranda-Lorenzo, I., Lonardo, E., Dorado, J., Vieira, C.R., Ramirez, J.C., Hidalgo, M., Aicher, A., et al.(2015). The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells . Gut. 64. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1936-1948.

Cioffi, M., Trabulo, S., Hidalgo, M., Costello, E., Greenhalf, W., Erkan, M., Kleeff, J., Sainz, B., Heeschen, C.(2015). Inhibition of CD47 Effectively targets pancreatic cancer stem cells via dual mechanisms . Clinical Cancer Research. 21. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2325-2337.

Cioffi M, D'Alterio C, Camerlingo R, Tirino V, Consales C, Riccio A, Ieranò C, Cecere SC, Losito NS, Greggi S, Pignata S, Pirozzi G, Scala S, Scientific reports, 2015, vol. 5, pp. 10357, 2015 .

Lonardo E, Cioffi M, Sancho P, Crusz S, Heeschen C, Journal of visualized experiments : JoVE, 2015, 2015 .

Sainz, B., Alcala, S., Garcia, E., Sanchez-Ripoll, Y., Azevedo, M.M., Cioffi, M., Tatari, M., Miranda-Lorenzo, I., Hidalgo, M., Gomez-Lopez, G., et al.(2015). Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment . Gut. 64. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1921-1935.

Lonardo, E., Cioffi, M., Sancho, P., Crusz, S., Heeschen, C.(2015). Studying pancreatic cancer stem cell characteristics for developing new treatment strategies . Journal of Visualized Experiments. 2015. (100).

Cioffi, M., Dalterio, C., Camerlingo, R., Tirino, V., Consales, C., Riccio, A., Ieranò, C., Cecere, S.C., Losito, N.S., Greggi, S., et al.(2015). Identification of a distinct population of CD133 + CXCR4 + cancer stem cells in ovarian cancer . Scientific Reports. 5.

Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D, Zagorac S, Balic A, Hidalgo M, Erkan M, Kleeff J, Scarpa A, Sainz B Jr, Heeschen C, Nature methods, 2014, vol. 11, no. 11, pp. 1161-1169 .

Balic A, Sørensen MD, Trabulo SM, Sainz B Jr, Cioffi M, Vieira CR, Miranda-Lorenzo I, Hidalgo M, Kleeff J, Erkan M, Heeschen C, Molecular cancer therapeutics, 2014, vol. 13, no. 7, pp. 1758-1771 .

Balic, A., Sørensen, M.D., Trabulo, S.M., Sainz Jr., B., Cioffi, M., Vieira, C.R., Miranda-Lorenzo, I., Hidalgo, M., Kleeff, J., Erkan, M., et al.(2014). Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling . Molecular Cancer Therapeutics. 13. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1758-1771.

Miranda-Lorenzo, I., Dorado, J., Lonardo, E., Alcala, S., Serrano, A.G., Clausell-Tormos, J., Cioffi, M., Megias, D., Zagorac, S., Balic, A., et al.(2014). Intracellular autofluorescence: A biomarker for epithelial cancer stem cells . Nature Methods. 11. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1161-1169.

Lonardo E, Cioffi M, Sancho P, Sanchez-Ripoll Y, Trabulo SM, Dorado J, Balic A, Hidalgo M, Heeschen C, PloS one, 2013, vol. 8, no. 10, pp. e76518 .

Lonardo, E., Cioffi, M., Sancho, P., Sanchez-Ripoll, Y., Trabulo, S.M., Dorado, J., Balic, A., Hidalgo, M., Heeschen, C.(2013). Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells . PLoS ONE. 8. (10).

Cioffi M, Heeschen C, Oncoimmunology, 2012, vol. 1, no. 4, pp. 560-562 .

Cioffi M, Dorado J, Baeuerle PA, Heeschen C, Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, vol. 18, no. 2, pp. 465-474 .

Cioffi, M., Heeschen, C.(2012). Immuno-targeting of pancreatic cancer stem cells: A new therapeutic strategy against a devastating disease? . OncoImmunology. 1. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 560-562.

D'Alterio C, Consales C, Polimeno M, Franco R, Cindolo L, Portella L, Cioffi M, Calemma R, Marra L, Claudio L, Perdonà S, Pignata S, Facchini G, Cartenì G, Longo N, Pucci L, Ottaiano A, Costantini S, Castello G, Scala S, Current cancer drug targets, 2010, vol. 10, no. 7, pp. 772-781 .

D'Alterio C, Cindolo L, Portella L, Polimeno M, Consales C, Riccio A, Cioffi M, Franco R, Chiodini P, Cartenì G, Mirone V, Longo N, Marra L, Perdonà S, Claudio L, Mascolo M, Staibano S, Falsaperla M, Puglisi M, Martignoni G, Ficarra V, Castello G, Scala S, Cell cycle (Georgetown, Tex.), 2010, vol. 9, no. 22, pp. 4492-4500 .

Hermann PC, Bhaskar S, Cioffi M, Heeschen C, Seminars in cancer biology, 2010, vol. 20, no. 2, pp. 77-84 .

Hermann, P.C., Bhaskar, S., Cioffi, M., Heeschen, C.(2010). Cancer stem cells in solid tumors . Seminars in Cancer Biology. 20. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 77-84.

D'Alterio, C., Consales, C., Polimeno, M., Franco, R., Cindolo, L., Portella, L., Cioffi, M., Calemma, R., Marra, L., Claudio, L., et al.(2010). Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer . Current Cancer Drug Targets. 10. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 772-781.

Ierano, C., Giuliano, P., D'Alterio, C., Cioffi, M., Mettivier, V., Portella, L., Napolitano, M., Barbieri, A., Arra, C., Liguori, G., et al.(2009). A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration . Cell Cycle. 8. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1228-1237.