プロフィール詳細

プロジェクトを作成

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Dr. Murugappan S.に依頼

United States

Biophysicist/Biochemist expertise in assay development for small/large molecule based early drug discovery research

プロフィール概要

Biochemist/Biophysicist with 12+ years of experience in expression, purification, and biophysical/biochemical characterization of soluble and membrane proteins. Expertise in protein-protein/peptide, protein-small molecule, peptide/protein-lipid, and protein-nucleic acid interactions progressing the early drug discovery research. Core competencies include: ● Demonstrated success in leading protein sciences group and designing/executing biochemical/biophysical assays for multiple programs ● Experience managing CRO resources (FFS & FTE model) for protein science and structural biology work. ● Experience leading biochemistry/biophysics group in a fast-paced environment ● Conscientious team player and collaborator with exemplary observational, analytical, and communication skills

専門分野

• ★ Biochemistry
• ★ Biophysics
• ★ Antibody Engineering
• ☆ Molecular Modeling
• ☆ Separation & Purification
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Lipidomics
• ☆ Recombinant Protein Expression
• ☆ Protein/Enzyme Engineering
• ☆ Drug Design
• ☆ Rare Diseases
• ☆ Cancer Research

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing, Newswriting

Research Market Research, User Research, Feasibility Study, Fact Checking, Gap Analysis, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Formulation, Product Validation

職務経験

Senior Scientist

Kymera Therapeutics

5月 2022 - 現在

Scientist II

Syros Pharmaceuticals Inc

7月 2020 - 現在

Senior Scientist

Syros Pharmaceuticals

2月 2022 - 4月 2022

Broad Institute

3月 2017 - 6月 2020

学歴

University of Connecticut

9月 2009 - 2月 2017

認定資格

• INTRODUCTION TO MOLECULAR MODELING IN DRUG DISCOVERY

  Schrodinger

  12月 2019 - 現在

• Light Scattering University

  Wyatt Technology Corporation

  12月 2018 - 現在

出版物

JOURNAL ARTICLE

Wayne Mitchell, Emily A. Ng, Jeffrey D. Tamucci, Kevin J. Boyd, Murugappan Sathappa, Adrian Coscia, Meixia Pan, Xianlin Han, Nicholas A. Eddy, Eric R. May, et al.(2020). The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action . Journal of Biological Chemistry. 295. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7452--7469. Elsevier {BV}