プロフィール詳細

プロジェクトを作成

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Mykola P.に依頼

Ukraine

Freelance molecular biologist with strong skills in drug design

プロフィール概要

I have been working in the field of rational drug development for 6 years. During this time I studied various methods of molecular modeling, including methods of virtual screening, chemoinformatics, bioinformatics, homologous modeling, etc. I'm currently the author of more than 13 articles on the development of new biologically active molecules for various molecular targets.

専門分野

• ★ Drug Design
• ☆ Molecular Modeling
• ☆ Molecular Docking
• ☆ Biology/Life Sciences
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Bioinformatics
• ☆ Medicinal Chemistry

サービス

• Writing
• Research

Writing Technical Writing

Research Systematic Literature Review

職務経験

Junior Research Scientist

Institute of Molecular Biology and Genetics National Academy of Sciences of Ukraine

12月 2017 - 現在

学歴

Master

Kyiv National Taras Shevchenko University

9月 2012 - 6月 2014

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2020). Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2 . Bioorganic Chemistry.

(2019). Identification and characterization of potential membrane-bound molecular drug targets of methicillin-resistant Staphylococcus aureus using in silico approaches . Biopolymers and Cell.

(2019). Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors . Biopolymers and Cell.

(2019). Hit identification of FGFR1 inhibitors using receptor-based virtual screening . Biopolymers and Cell.

(2019). The use of the docking studies with the purpose of searching Potential Antihypertensive Drugs . Research Journal of Pharmacy and Technology.

Protopopov, M.V., Volynets, G.P., Starosyla, S.A., Vdovin, V.S., Lukashov, S.S., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.(2018). Identification of 1,3-thiazole-5-carboxylic acid derivatives as inhibitors of protein kinase CK2 . Current Enzyme Inhibition. 14. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 152-159.

Protopopov, M.V., Ostrynska, O.V., Starosyla, S.A., Vodolazhenko, M.A., Sirko, S.M., Gorobets, N.Y., Bdzhola, V., Desenko, S.M., Yarmoluk, S.M.(2018). Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors . Molecular Diversity. 22. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 991-998.

Drapak, I., Perekhoda, L., Vynogradova, O., Protopopov, M., Suleiman, M., Sych, I., Kobzar, N., Kiz, O.(2018). The use of the docking studies with the purpose of searching potential cardioprotectors . Pharmacia. 65. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 40-46.

Protopopov, M.V., Ostrynska, O.V., Ivanchenko, D.H., Starosyla, S.A., Bdzhola, V.G., Romanenko, M.I., Yarmoluk, S.M.(2017). Search of protein kinase CK2 inhibitors based on purine-2,6-Diones derivatives . Ukrainian Biochemical Journal. 89. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 32-39.

Protopopov, M.V., Starosyla, S.A., Borovykov, O.V., Sapelkin, V.N., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.(2017). Hit identification of CK2 inhibitors by methods of virtual screening . Biopolymers and Cell. 33. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 291-301.

Zinchenko, A.N., Muzychka, L.V., Smolii, O.B., Bdzhola, V.G., Protopopov, M.V., Yarmoluk, S.M.(2017). Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2 . Biopolymers and Cell. 33. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 367-378.

Gudzera, O.I., Golub, A.G., Bdzhola, V.G., Volynets, G.P., Kovalenko, O.P., Boyarshin, K.S., Yaremchuk, A.D., Protopopov, M.V., Yarmoluk, S.M., Tukalo, M.A.(2016). Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one . Journal of Enzyme Inhibition and Medicinal Chemistry. 31. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 201-207.

Starosyla, S.A., Volynets, G.P., Bdzhola, V.G., Golub, A.G., Protopopov, M.V., Yarmoluk, S.M.(2014). ASK1 pharmacophore model derived from diverse classes of inhibitors . Bioorganic and Medicinal Chemistry Letters. 24. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4418-4423.