プロフィール詳細

プロジェクトを作成

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Dr. Natalia S.に依頼

United Kingdom

Experienced Cancer Researcher with Project/Personnel Management Skills and an Aptitude for Scientific Writing

プロフィール概要

As a former Instructor/Junior Faculty (MD Anderson Cancer Center, Houston, TX, USA), I have a strong knowledge base in cancer biology, and proven skills in grantsmanship and scientific writing. I can help improve the clarity and flow of your text, highlight key findings to accentuate impact, iron out inconsistencies, format the text as per the target journal's or funding agency's guidelines, and tailor proposals to the funding call. I can also comment on the scientific content and referencing, and help pre-empt referee concerns by suggesting additional experiments, if necessary. I have considerable experience of working with non-native English speakers, and I am familiar with both British and American written English. • Research track record in breast cancer basic and translational research, epithelial-mesenchymal transition (EMT), mesenchymal-epithelial-transition (MET), cancer stem cells (CSCs), metastasis, epigenetics, pancreas acinar-ductal transdifferentiation, embryonic stem cells, apoptosis, cell cycle checkpoints, p53, and signal transduction • Published >20 peer-reviewed research papers, reviews, editorial/opinion articles, and abstracts • Co-Investigator/co-author of US and UK grants (NIH/R01: $1,599,295; American Cancer Society: $800,000; METAvivor: $80,000; BBSRC: £256,388) • Technical expertise in molecular and cell biology, biochemistry, and preclinical models • Served as ad hoc peer-reviewer for 9 scientific journals (PNAS, Mol Cell Biol, JNCI, BMC Cancer, Future Oncology, Clinical and Translational Medicine, Gut, Clin Exp Metastasis, Carcinogenesis) • Proofread, fact-checked, and critiqued multiple grant proposals, fellowship applications, manuscripts, and 4 PhD/MPhil theses

専門分野

• ★ Stem Cell Research
• ★ Oncology
• ☆ Biology/Life Sciences
• ☆ Developmental Biology
• ☆ Biochemistry
• ☆ Apoptosis
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Epigenetics
• ☆ Cytochemistry
• ☆ Cell Signaling Pathways
• ☆ Basic Immunology
• ☆ Microscopy
• ☆ Bioinformatics
• ☆ Clinical Trials
• ☆ Medical Sciences
• ☆ Cancer Research
• ☆ Carcinogenesis
• ☆ Metabolism & Metabolic Disease
• ☆ Peer Review
• ☆ Fact Checking

サービス

• Writing
• Consulting
• Product Development

職務経験

Scientific Writer

Beatson Institute for Cancer Research

2018 - 現在

Freelance Science Writer

Cactus Communications

2016 - 2018

Instructor/Junior Faculty

University of Texas MD Anderson Cancer Center

2009 - 2015

Post-doctoral Research Fellow

University of Edinburgh

2004 - 2008

Post-doctoral Research Fellow

University of Edinburgh

1999 - 2004

Post-doctoral Research Scientist

University of Edinburgh

1995 - 1998

学歴

PhD (Biological Sciences)

University of Warwick

1990 - 1995

BSc (Hons) Biochemistry (Biological Sciences)

University of Warwick

1987 - 1990

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2019). GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer . Breast cancer research : BCR.

(2017). The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition . Oncotarget.

(2016). Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties . Oncogene.

(2016). Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth . Oncogene.

(2016). FOXC2 regulates the G2/M transition of stem cell-rich breast cancer cells and sensitizes them to PLK1 inhibition . Scientific Reports.

(2016). Mathematical modelling of phenotypic plasticity and conversion to a stem-cell state under hypoxia . Scientific reports.

(2015). EMT-induced metabolite signature identifies poor clinical outcome . Oncotarget.

(2015). GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer . Oncogene.

(2015). GD2 and GD3 synthase: novel drug targets for cancer therapy . Molecular & Cellular Oncology.

(2013). FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer . Cancer research.

(2013). Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties . Scientific reports.

(2011). pIgR: frenemy of inflammation, EMT, and HCC progression . Journal of the National Cancer Institute.

(2011). Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression . Breast cancer research : BCR.

(2007). The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members . Molecular and Cellular Biology.

(2005). p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells . Oncogene.

(2005). Improved retention of zymogen granules in cultured murine pancreatic acinar cells and induction of acinar-ductal transdifferentiation in vitro . Pancreas.

(2004). p73alpha is a candidate effector in the p53 independent apoptosis pathway of cisplatin damaged primary murine colonocytes . Journal of clinical pathology.

(1996). Apoptosis in vivo and in vitro: conflict or complementarity? . Molecular medicine today.

(1995). Mutational analysis of the Ricinus lectin B-chains. Galactose-binding ability of the 2 gamma subdomain of Ricinus communis agglutinin B-chain . The Journal of biological chemistry.

DISSERTATION THESIS

Sphyris N(2010). Studies on agglutinin from Ricinus communis : comparison with ricin .