プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Oluwatayo I.に依頼

United States

Skilled biomedical researcher with multidisciplinary expertise in translational molecular imaging and immuno-oncology

プロフィール概要

Detail oriented biological chemist (Ph.D. and postdoctoral training) with expertise navigating biotech-industry and academic research. 10+ years experience developing targeted biological therapeutics and surrogate diagnostic imaging assays to facilitate IND-enabling pharmacokinetics, pharmacodynamics, and mechanism of action studies. Experimentalist with hands on skills in biomolecule (proteins/peptides/antibodies/antibody drug conjugates) chemistry, preclinical nuclear imaging sciences, companion diagnostics and theranostics. Demonstrated ability to coordinate and deliver results for interdisciplinary projects; independent developer of in vitro, in vivo, and ex vivo assays to support drug development initiatives in various therapeutic areas including oncology, cardiovascular and metabolic disorders, neuroscience, and immuno-oncology. Extensive experience leading initiative for the development and validation of in vivo immune-imaging reagents to enable mechanism of action studies for immunotherapy programs including bispecific T cell engagers, cell and gene therapies, and immune checkpoint inhibitors. Core skills include wide array of laboratory techniques, experimental design, writing scientific papers and grant proposals. I have demonstrated ability to manage and conduct both translational research projects.

専門分野

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Molecular Biology
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Biomarker Discovery
• ☆ Cytometry
• ☆ Drug Development
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ Drug Efficacy Testing
• ☆ Medical Imaging/Radiology
• ☆ Nuclear Medicine
• ☆ Pulmonology/Respiratory Disease
• ☆ Lung Cancer
• ☆ Computed Tomography (CT)
• ☆ Positron Emission Tomography (PET)
• ☆ Immunotherapy
• ☆ Gene Therapy
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Nuclear Radiology
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Instructional Webinars
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Audio Transcription
• ☆ Grant Writing

サービス

• Writing
• Research
• Consulting

Writing Technical Writing, General Proofreading & Editing

Research Feasibility Study, Scientific and Technical Research, Secondary Data Collection

Consulting Healthcare Consulting, Scientific and Technical Consulting

職務経験

Assistant Professor / Associate Professor

University of California Los Angeles

1月 2020 - 現在

Senior Scientist

Bristol-Myers Squibb

10月 2017 - 1月 2020

Scientist

Amgen Inc

10月 2013 - 9月 2017

Postdoctoral Associate/Fellow

Washington University School of Medicine

8月 2009 - 10月 2009

学歴

Ph.D. Biological Chemistry

Syracuse University

5月 2005 - 6月 2009

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Nagle VL, Ikotun OF, Kelly Henry (2022). A Highlight on Dr. Julie C. Price: an Exceptional Career and a Candid Conversation on Diversity, Equity, and Inclusion . Molecular imaging and biology.

Akam E, E. Carmen, Aisling Chaney, Dhanvantari S, Edwards KJ, Kelly Henry, Ibhagui OY, Ijoma JN, Ikotun OF, Mack KN, et al. (2021). Visions by Women in Molecular Imaging Network: Antiracism and Allyship in Action . Molecular imaging and biology.

Foti RS, Biswas K, Aral J, Be X, Berry L, Cheng Y, Conner K, Falsey JR, Glaus C, Herberich B, et al. (2019). Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species . Drug metabolism and disposition: the biological fate of chemicals.

Justin Murray, Bin Wu, Tegley CM, Nixey TE, Falsey JR, Herberich B, Yin L, Sham K, Long J, Aral J, et al. (2019). Engineering Na_V1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics . ACS chemical biology.

Moesta AK, Cooke K, Piasecki J, Mitchell P, Rottman JB, Fitzgerald K, Zhan J, Yang B, Le T, Belmontes B, et al. (2017). Local Delivery of OncoVEX^mGM-CSF Generates Systemic Antitumor Immune Responses Enhanced by Cytotoxic T-Lymphocyte-Associated Protein Blockade . Clinical cancer research : an official journal of the American Association for Cancer Research.

Marquez BV, Ikotun OF, Zheleznyak A, Wright B, Amrita Hari-Raj, MD, Pierce RA, Suzanne Lapi (2014). Evaluation of (89)Zr-pertuzumab in Breast cancer xenografts . Molecular pharmaceutics.

Ikotun OF, Marquez BV, Fazen CH, Kahkoska AR, Doyle RP, Suzanne Lapi (2014). Investigation of a vitamin B12 conjugate as a PET imaging probe . ChemMedChem.

Marquez BV, Ikotun OF, Parry JJ, Rogers BE, Meares CF, Suzanne Lapi (2014). Development of a Radiolabeled Irreversible Peptide Ligand for PET Imaging of Vascular Endothelial Growth Factor . Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Zheleznyak A, Ikotun OF, Dimitry J, Frazier WA, Suzanne Lapi (2013). Imaging of CD47 expression in xenograft and allograft tumor models . Molecular imaging.

Ikotun OF, Marquez BV, Huang C, Masuko K, Daiji M, Masuko T, McConathy J, Lapi SE (2013). Imaging the L-type amino acid transporter-1 (LAT1) with Zr-89 immunoPET . PloS one.

Ikotun OF, Suzanne Lapi (2011). The rise of metal radionuclides in medical imaging: copper-64, zirconium-89 and yttrium-86 . Future medicinal chemistry.

Nadia Marino, Ikotun OF, Julve M, Lloret F, Cano J, Doyle RP (2010). Pyrophosphate-mediated magnetic interactions in Cu(II) coordination complexes . Inorganic chemistry.

Ikotun OF, Higbee EM, Ouellette W, Doyle RP (2009). Pyrophosphate-bridged complexes with picomolar toxicity . Journal of inorganic biochemistry.

Ikotun OF, Higbee EM, Ouellette W, Doyle RP (2009). Pyrophosphate-bridged complexes with picomolar toxicity . Journal of inorganic biochemistry.

Ikotun OF, Armatus NG, Julve M, Paul E. Kruger, Lloret F, Nieuwenhuyzen M, Doyle RP (2007). Synthesis and structural and magnetic characterization of {[(phen)(2)Ni](2)(micro-P(2)O(7))} . 27H(2)O and {[(phen)(2)Mn](2)(micro-P(2)O(7))} . 13H(2)O: rare examples of coordination complexes with the pyrophosphate ligand . Inorganic chemistry.