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プロフィール詳細
プロフィール概要
専門分野
サービス
Writing
Technical Writing
Research
Market Research,
User Research,
Fact Checking,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Predictive Modeling,
Statistical Analysis,
Algorithm Design-Non ML,
Big Data Analytics,
Data Processing,
Data Insights
Product Development
Formulation,
Product Evaluation
職務経験
Data Scientist
One Drop
4月 2021 - 5月 2022 
Software Engineer
Exos (United States)
1月 2020 - 8月 2020
Assistant Professor
Fordham University
8月 2013 - 8月 2019
Software Developer
Schrodinger LLC New York Office
3月 2010 - 11月 2010
学歴
PhD (Biological Sciences)
Columbia University
9月 2000 - 10月 2005
Bachelors
Columbia College
9月 1995 - 4月 1999
認定資格
-
End-to-End Machine Learning with TensorFlow on Google Cloud
coursera
https://coursera.org/share/e990cc3db2445e96adcfecb278b9b6376月 2022 - 現在
出版物
JOURNAL ARTICLE
Tiffany Yip and Paul Smith and Michael Tynes and Sheena Mirpuri and Ashley Weems and Yuen Mi Cheon(2021). Discrimination and hair cortisol concentration among asian, latinx and white young adults . Comprehensive Psychoneuroendocrinology. 6. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 100047. Elsevier {BV}
(2019). Prediction of models for ordered solvent in macromolecular structures by a classifier based upon resolution-independent projections of local feature data . Acta crystallographica. Section D, Structural biology.
Smith, Paul and Ho, C. Kiong and Takagi, Yuko and Djaballah, Hakim and Shuman, Stewart(2016). Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase . MBio. 7. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e00058--00016.
Unciuleac, Mihaela-Carmen and Smith, Paul C. and Shuman, Stewart(2016). Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858) . J. Bacteriol. 198. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1521--1533.
Jacewicz, Agata and Chico, Lidia and Smith, Paul and Schwer, Beate and Shuman, Stewart(2015). Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs . RNA. 21. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 401--414.
Das, Ushati and Wang, Li Kai and Smith, Paul and Munir, Annum and Shuman, Stewart(2014). Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide . J. Bacteriol. 196. (24). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4285--4292.
Jacewicz, Agata and Schwer, Beate and Smith, Paul and Shuman, Stewart(2014). Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28 . Nucleic Acids Res. 42. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12885--12898.
Chakravarty, Anupam K. and Smith, Paul and Jalan, Radhika and Shuman, Stewart(2014). Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination . Cell Rep. 7. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 339--347.
Boël, Grégory and Smith, Paul C. and Ning, Wei and Englander, Michael T. and Chen, Bo and Hashem, Yaser and Testa, Anthony J. and Fischer, Jeffrey J. and Wieden, Hans-Joachim and Frank, Joachim and Gonzalez, Ruben L. and Hunt, John F.(2014). The ABC-F protein EttA gates ribosome entry into the translation elongation cycle . Nat. Struct. Mol. Biol. 21. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 143--151.
Das, Ushati and Wang, Li Kai and Smith, Paul and Jacewicz, Agata and Shuman, Stewart(2014). Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP•Mg2+ and 5'-OH oligonucleotide and a product complex with GDP•Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition . Nucleic Acids Res. 42. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1152--1161.
Das, Ushati and Wang, Li Kai and Smith, Paul and Shuman, Stewart(2013). Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkp•hen1 RNA repair system . Biochemistry. 52. (27). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4734--4743.
Wang, Li Kai and Smith, Paul and Shuman, Stewart(2013). Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system . Nucleic Acids Res. 41. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5864--5873.
Wang, Li Kai and Das, Ushati and Smith, Paul and Shuman, Stewart(2012). Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system . RNA. 18. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2277--2286.
Smith, Paul and Wang, Li Kai and Nair, Pravin A. and Shuman, Stewart(2012). The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family . Proc. Natl. Acad. Sci. U.S.A. 109. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2296--2301.
Das, Ushati and Smith, Paul and Shuman, Stewart(2012). Structural insights to the metal specificity of an archaeal member of the LigD 3'-phosphoesterase DNA repair enzyme family . Nucleic Acids Res. 40. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 828--836.
Chakravarty, Anupam K. and Smith, Paul and Shuman, Stewart(2011). Structures of RNA 3'-phosphate cyclase bound to ATP reveal the mechanism of nucleotidyl transfer and metal-assisted catalysis . Proc. Natl. Acad. Sci. U.S.A. 108. (52). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 21034--21039.
Tanaka, Naoko and Smith, Paul and Shuman, Stewart(2011). Crystal structure of Rcl1, an essential component of the eukaryal pre-rRNA processosome implicated in 18s rRNA biogenesis . RNA. 17. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 595--602.
Smith, Paul and Nair, Pravin A. and Das, Ushati and Zhu, Hui and Shuman, Stewart(2011). Structures and activities of archaeal members of the LigD 3'-phosphoesterase DNA repair enzyme superfamily . Nucleic Acids Res. 39. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3310--3320.
Samai, Poulami and Smith, Paul and Shuman, Stewart(2010). Structure of a CRISPR-associated protein Cas2 from Desulfovibrio vulgaris . Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66. (Pt 12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1552--1556.
Nair, Pravin A. and Smith, Paul and Shuman, Stewart(2010). Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily . Proc. Natl. Acad. Sci. U.S.A. 107. (29). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12822--12827.
Tanaka, Naoko and Smith, Paul and Shuman, Stewart(2010). Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer . Structure. 18. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 449--457.
Benarroch, Delphine and Smith, Paul and Shuman, Stewart(2008). Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domain . Structure. 16. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 501--512.
Zhu, Hui and Smith, Paul and Wang, Li Kai and Shuman, Stewart(2007). Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase . Virology. 366. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 126--136.
Nair, Pravin A. and Nandakumar, Jayakrishnan and Smith, Paul and Odell, Mark and Lima, Christopher D. and Shuman, Stewart(2007). Structural basis for nick recognition by a minimal pluripotent DNA ligase . Nat. Struct. Mol. Biol. 14. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 770--778.
Gong, Chunling and Smith, Paul and Shuman, Stewart(2006). Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins . RNA. 12. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1468--1474.
Karpowich, Nathan K. and Huang, Hector H. and Smith, Paul C. and Hunt, John F.(2003). Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding . J. Biol. Chem. 278. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8429--8434.
Benach, Jordi and Chou, Yi-Te and Fak, John J. and Itkin, Anna and Nicolae, Daita D. and Smith, Paul C. and Wittrock, Guenther and Floyd, Daniel L. and Golsaz, Cyrus M. and Gierasch, Lila M. and Hunt, John F.(2003). Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA . J. Biol. Chem. 278. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3628--3638.
Keller, Jacob P. and Smith, Paul M. and Benach, Jordi and Christendat, Dinesh and deTitta, George T. and Hunt, John F.(2002). The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase. Structure. 10. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1475--1487.
Smith, Paul C. and Karpowich, Nathan and Millen, Linda and Moody, Jonathan E. and Rosen, Jane and Thomas, Philip J. and Hunt, John F.(2002). ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol. Cell. 10. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 139--149.
Smith, Paul C. and Firestein, Stuart and Hunt, John F.(2002). The crystal structure of the olfactory marker protein at 2.3 A resolution . J. Mol. Biol. 319. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 807--821.
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