プロフィール詳細

プロジェクトを作成

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Dr. Pedro G.に依頼

Taiwan

Enthusiastic scientist | Fungal biologist | Freelance scientific editor | Global experience | Reach out to learn more

プロフィール概要

I see myself as a global player. I have worked in Europe, America and Asia, and I value human diversity very much. I am a respectful and lucid independent thinker, and have broad interests in life. I am a good communicator and I have co-mentored students. I am a team player but know when to work autonomously. I like writing and my skills have been praised by all my supervisors (I hold a specialization in scientific writing). I was initially trained at the bachelor’s level as a biomedical scientist. I earned a PhD in Molecular Pathology and Genetics, in 2014, from the University of Porto (approved with distinction; Calouste Gulbenkian Foundation fellowship). During the course of my PhD, I had the chance to acquire some teaching experience as well as to conduct research at the University of Edinburgh and University of California, Berkeley (the latter supported by an EMBO fellowship). My PhD dissertation revolved around the molecular mechanisms of cell death and drug resistance in fungal and cancer cells (reviewed in Gonçalves et al. Front Microbiol, 2017). I then joined the University of Berkeley, California as a postdoctoral fellow (2015-2018). This was a great chapter in my career and a period of important scientific output, including publications and grants (including a proposal to the National Science Foundation that resulted in a $900K award). My work helped to explain how a fungal immune system determines social cooperation and multicellularity (Gonçalves et al. Curr Biol, 2019; Gonçalves et al. Annu Rev Microbiol, 2020). During the same period, I was one of the team leaders at The Millet Project, a non-profit outreach initiative on diet diversification and promotion of sustainable agriculture practices by connecting farmers, consumers, food professionals and scientists. I then became a postdoctoral scientist at Academia Sinica, where I studied a group of carnivorous fungi that trap and feed on nematodes. These microbes hold great potential as biological control agents in agricultural settings. In 2021, I became a visiting assistant professor at the National Cheng Kung University, in Taiwan, where I am a group leader running a small fungal biology laboratory. I have also served as a consultant for the biotechnology industry, at Geltor, Kismet Labs and Zermatt. My research has led to a significant number of publications and presentations in conferences, and I have served as a reviewer for various scientific journals. I served as a guest editor of two journal special issues at the Journal of Fungi and Frontiers in Bioengineering and Biotechnology. -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Skills: Scientific writing and editing (manuscripts, grant proposals, dissertations, reports) | Student mentoring | Bilingual | Statistical analysis | Image analysis | Fungal, bacterial, mammalian and nematode cell manipulation | Confocal and electron microscopy | Live-cell imaging | DNA and amino acid sequence analysis | Isolation of nucleic acids | Conventional and real time PCR | Electrophoresis | Molecular cloning | Generation of gene deletion mutants | Site-directed mutagenesis | cDNA library construction | RNA-seq | Spectrophotometry and luminometry | Flow cytometry | Western blot | Chromatin immunoprecipitation | Electrophoretic mobility shift assay | Website management -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Outreach: The Millet Project -- https://themilletproject.org/ -- Science outreach, sustainable agriculture, product development, culinary arts and crowdfunding | Clubes de Ciencia Mexico 2017 -- Science education program aimed at high school and early undergraduate students | Content developer for an online exhibition on soil biodiversity -- Emirates Soil Museum/International Center for Biosaline Agriculture -- https://www.emiratessoilmuseum.org/digital-exhibition -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Languages: Portuguese (native), english (fluent), spanish (good), french (fair), mandarin (basic) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- LIST OF PUBLICATIONS  Li Y, …, Gonçalves AP, et al. mBio, 2021 | 10.1128/mBio.00307-21  Gonçalves AP, et al. Annu Rev Microbiol, 2020 | 10.1146/annurev-micro-012420-080905  Gonçalves AP, et al. Commun Integr Biol, 2020 | 10.1080/19420889.2020.1740554  Yang CT, Vidal-Diez de Ulzurrun G, Gonçalves AP, et al. Proc Natl Acad Sci U S A, 2020 | 10.1073/pnas.1919726117  Gonçalves AP, et al. Front Microbiol, 2020 | 10.3389/fmicb.2019.03162  Gonçalves AP, et al. J Fungi, 2019 | 10.3390/jof5040114  Gonçalves AP, et al. Curr Biol, 2019 | 10.1016/j.cub.2019.07.060  Celestino R, …, Gonçalves AP, et al. BMC Cancer, 2018 | 10.1186/s12885-017-3948-3  Starr TL, Gonçalves AP, et al. Mol Microbiol, 2017 | 10.1111/mmi.13879  Gonçalves AP, et al. Front Microbiol, 2017 | 10.3389/fmicb.2017.01837  Vinagre J, …, Gonçalves AP, et al. Sci Rep, 2016 | 10.1038/srep29714  Gonçalves AP, et al. Biochim Biophys Acta-Bioenergetics, 2015 | 10.1016/j.bbabio.2015.05.011  Palma-Guerrero J, Zhao J, Gonçalves AP, et al. Eukaryot Cell, 2015 | 10.1128/EC.00233-14  Gonçalves AP, Videira A. Microb Cell, 2015 | 10.15698/mic2015.03.192  Gonçalves AP, et al. Genom Data, 2015 | 10.1016/j.gdata.2015.02.001  Gonçalves AP, et al. Microb Cell, 2015 | 10.15698/mic2014.09.165  Gonçalves AP, et al. J Cell Sci, 2014 | 10.1242/jcs.152058  Gonçalves AP, et al. G3-Genes, Genomes, Genetics, 2014 | 10.1534/g3.114.011312  Gonçalves AP, Videira A. New J Sci, 2014 | 10.1155/2014/479015  Fernandes AS, Gonçalves AP, et al. Fungal Genet Biol, 2011 | 10.1016/j.fgb.2011.09.004  Gonçalves AP, et al. J Biosci, 2011 | 10.1007/s12038-011-9100-7  Gonçalves AP, et al. Life Sci, 2011 | 10.1016/j.lfs.2011.07.004  Gonçalves AP, et al. Biochim Biophys Acta-Mol Cell Res, 2011 | 10.1016/j.bbamcr.2011.01.006

専門分野

• ★ Mycology
• ☆ Biology/Life Sciences
• ☆ Microbiology
• ☆ Mycology/Fungi
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Chromatin
• ☆ PCR
• ☆ RNA Sequencing
• ☆ Microbial Biotechnology
• ☆ Microscopy
• ☆ Agriculture
• ☆ Biological Engineering
• ☆ Environmental Biotechnology
• ☆ Biodiversity
• ☆ Blotting
• ☆ Phylogenetics
• ☆ Population Genetics
• ☆ Cytometry
• ☆ Science Outreach
• ☆ Spanish
• ☆ Sustainable Development

サービス

• Writing
• Research
• Data & AI

Writing Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis

職務経験

Visiting Assistant Professor

National Cheng Kung University

4月 2021 - 現在

Scientific Consultant

Zermatt

1月 2021 - 3月 2021

Scientific Consultant

Kinoko Labs

1月 2021 - 2月 2021

Postdoctoral Scientist

Academia Sinica, Institute of Molecular Biology

3月 2019 - 12月 2020

Postdoctoral Scientist

University of California - Berkeley, Department of Plant and Microbial Biology

2月 2015 - 11月 2018

Scientific Consultant

Geltor, Inc.

6月 2018 - 9月 2018

Research Assistant

Institute of Molecular Pathology and Immunology of the University of Porto

8月 2014 - 12月 2014

PhD candidate

Abel Salazar Biomedical Sciences Institute and Institute for Molecular and Cell Biology of the University of Porto

8月 2009 - 7月 2014

学歴

PhD, Molecular Pathology and Genetics

University of Porto

1月 2010 - 7月 2014

BSc, Anatomical Pathology, Cytology and Thanatology

Porto Polytechnic

9月 2004 - 6月 2008

認定資格

• English for Research Publication Purposes (4 courses & capstone project)

  Moscow Institute of Physics and Technology

  https://www.coursera.org/

  10月 2019 - 現在

出版物

JOURNAL ARTICLE

(2020). Conflict, Competition, and Cooperation Regulate Social Interactions in Filamentous Fungi . Annual Review of Microbiology.

(2020). Drought Drives Spatial Variation in the Millet Root Microbiome . Frontiers in Plant Science.

(2020). Natural diversity in the predatory behavior facilitates the establishment of a robust model strain for nematode-trapping fungi . Proceedings of the National Academy of Sciences.

(2020). WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex . Frontiers in Microbiology.

A. Pedro Gonçalves, N. Louise Glass(2020). Fungal social barriers: to fuse, or not to fuse, that is the question . Communicative & Integrative Biology. 13. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 39--42. Informa {UK} Limited

A. Pedro Gonçalves, Kevin McCluskey, N. Louise Glass, Arnaldo Videira(2019). The Fungal Cell Death Regulator czt-1 Is Allelic to acr-3 . Journal of Fungi. 5. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 114. {MDPI} {AG}

A Pedro Gon&#231;alves, Kevin McCluskey, N. Louise Glass, Arnaldo Videira (2019). The Fungal Cell Death Regulator <i>czt-1</i> Is Allelic to <i>acr-3</i> . Journal of Fungi.

(2019). Allorecognition upon Fungal Cell-Cell Contact Determines Social Cooperation and Impacts the Acquisition of Multicellularity . Current Biology.

(2018). CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension . BMC cancer.

(2017). The major cellulases CBH-1 and CBH-2 of Neurospora crassa rely on distinct ER cargo adaptors for efficient ER-exit . Molecular microbiology.

(2017). Regulated Forms of Cell Death in Fungi . Frontiers in microbiology.

(2016). TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes . Scientific reports.

A. Pedro Gon&#231;alves, J. Miguel Cordeiro, Jo&#227;o Monteiro, Chiara Lucchi, Paulo Correia-de-S&#225;, Arnaldo Videira(2015). Involvement of mitochondrial proteins in calcium signaling and cell death induced by staurosporine in Neurospora crassa . Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1847. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1064--1074. Elsevier {BV}

(2015). Mitochondrial type II NAD(P)H dehydrogenases in fungal cell death . Microbial cell (Graz, Austria).

(2015). Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone . Genomics data.

Javier Palma-Guerrero, Jiuhai Zhao, A. Pedro Gon&#231;alves, Trevor L. Starr, N. Louise Glass(2015). Identification and Characterization of LFD-2, a Predicted Fringe Protein Required for Membrane Integrity during Cell Fusion in Neurospora crassa . Eukaryotic Cell. 14. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 265--277. American Society for Microbiology

(2014). Extracellular calcium triggers unique transcriptional programs and modulates staurosporine-induced cell death in Neurospora crassa . Microbial cell (Graz, Austria).

A. P. Goncalves, J. M. Cordeiro, J. Monteiro, A. Munoz, P. Correia-de-Sa, N. D. Read, A. Videira(2014). Activation of a TRP-like channel and intracellular Ca2+ dynamics during phospholipase-C-mediated cell death . Journal of Cell Science. 127. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3817--3829. The Company of Biologists

A. P. Goncalves, C. Hall, D. J. Kowbel, N. L. Glass, A. Videira(2014). CZT-1 Is a Novel Transcription Factor Controlling Cell Death and Natural Drug Resistance in Neurospora crassa . G3&amp;#58; Genes|Genomes|Genetics. 4. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1091--1102. Genetics Society of America

A. Pedro Gon&#231;alves, Arnaldo Videira(2014). Programmed Cell Death in Neurospora crassa . New Journal of Science. 2014. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--7. Hindawi Publishing Corporation

Goncalves, A. P., Videira, A., Maximo, V., Soares, P.(2011). Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death. J Biosci. 36. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 639-48.

Gon&#231;alves, A. P., M&#225;ximo, V., Lima, J., Singh, K. K., Soares, P., Videira, A.(2011). Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone . Biochim Biophys Acta. 1813. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 492-9.

Fernandes, A. S., Gon&#231;alves, A. P., Castro, A., Lopes, T. A., Gardner, R., Glass, N. L., Videira, A.(2011). Modulation of fungal sensitivity to staurosporine by targeting proteins identified by transcriptional profiling . Fungal Genet Biol. 48. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1130-8.

Gon&#231;alves, A. P., Videira, A., Soares, P., M&#225;ximo, V.(2011). Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR . Life Sci. 89. (11-12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 371-7.