プロフィール詳細

プロジェクトを作成

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Dr. Phillip B.に依頼

United States

Expert in biochemistry and molecular biology, assay development, diagnostics | 13 years experience academia + R&D

プロフィール概要

I have worked on diagnostic assay development for a next-gen immunoassay, custom genome synthesis, and on development of protein therapeutics; graduate work centered on DNA replication and repair enzymes. My skills are broad and include DNA synthesis and purification, cloning, protein expression and purification, surface chemistry, small-molecule conjugation to proteins and DNA, enzymatic activity assays, electrochemistry, and spectroscopy.

専門分野

• ☆ Surface Science
• ☆ Electrochemistry
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Recombinant DNA
• ☆ DNA/Gene Synthesis
• ☆ Oligonucleotide Synthesis
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Applied Chemistry
• ☆ Synthetic Biology
• ☆ Chemical Biology

サービス

• Writing
• Consulting

Writing Technical Writing

Consulting Scientific and Technical Consulting

職務経験

Senior Scientist

QuidelOrtho

9月 2022 - 7月 2024

Scientist I

Telesis Bio

8月 2021 - 9月 2022

Postdoctoral Scholar

University of California San Diego

9月 2018 - 8月 2021

学歴

PhD (Chemistry)

California Institute of Technology

9月 2011 - 2月 2018

BA (Biological Sciences)

University of Chicago

9月 2007 - 6月 2011

BS (Chemistry)

University of Chicago

9月 2007 - 6月 2011

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

McDonnell, K.J., Chemler, J.A., Bartels, P.L., O’Brien, E., Marvin, M.L., Ortega, J., Stern, R.H., Raskin, L., Li, G.-M., Sherman, D.H., et al.(2018). A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S]²⁺ cluster . Nature Chemistry. 10. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 873-880.

Bartels, P.L., Stodola, J.L., Burgers, P.M.J., Barton, J.K.(2017). A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ . Journal of the American Chemical Society. 139. (50). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 18339-18348.

Ha, Y., Arnold, A.R., Nu&#241;ez, N.N., Bartels, P.L., Zhou, A., David, S.S., Barton, J.K., Hedman, B., Hodgson, K.O., Solomon, E.I.(2017). Sulfur K-Edge XAS Studies of the Effect of DNA Binding on the [Fe<inf>4</inf>S<inf>4</inf>] Site in EndoIII and MutY . Journal of the American Chemical Society. 139. (33). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11434-11442.

Bartels, P.L., Zhou, A., Arnold, A.R., Nu&#241;ez, N.N., Crespilho, F.N., David, S.S., Barton, J.K.(2017). Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA . Langmuir. 33. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2523-2530.

BOOK

Bartels, P.L., O&#39;Brien, E., Barton, J.K.(2017). DNA signaling by iron-sulfur cluster proteins . Biochemistry, Biosynthesis and Human Diseases: Biochemistry, Biosynthesis, and Human Diseases. 2. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 405-423.

Barton, J.K., Bartels, P.L., Deng, Y., O&#39;Brien, E.(2017). Electrical Probes of DNA-Binding Proteins . Methods in Enzymology. 591. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 355-414.