プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Ravi B.に依頼

United States

Experienced Scientist | Immunology | Antibody Discovery & Engineering | Biologics Development | Translational Research

プロフィール概要

A highly motivated scientist with a strong background in immunology, cell and molecular biology, and antibody discovery. Passionate about advancing future therapeutics from discovery to delivery, with expertise in cutting-edge biotechnologies, including in vitro display technologies, antibody engineering, and molecular pharmacology. Adept at driving research initiatives, collaborating across multidisciplinary teams, and contributing to the development of innovative biologics. Seeking to leverage scientific expertise in a dynamic industry setting to support breakthrough discoveries and pipeline development.

専門分野

• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Parasitology
• ☆ Microbiological Assays
• ☆ Zoology
• ☆ Mammalian Biology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Apoptosis
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Mutagenesis
• ☆ Recombinant DNA
• ☆ Oligonucleotide Synthesis
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Kinases
• ☆ Monoclonal Antibody Production
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Electron Microscopy
• ☆ Fluorescence Microscopy
• ☆ Scanning Probe Microscopy
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cytometry
• ☆ Cell Aging

サービス

• Research
• Consulting

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

職務経験

Senior Scientist / Group Manager

Umass Medical school

2月 2024 - 現在

Postdoc

UMass Memorial Medical Center University Campus

4月 2018 - 現在

Scientists

MassBiologics

2月 2023 - 2月 2024

学歴

Doctor of Philosophy (Ph.D)

Jawaharlal Nehru Centre for Advanced Scientific Research - India

8月 2010 - 6月 2017

認定資格

• Academic Certification in Biofeedback

  Biofeedback Certification International Alliance

  1月 2025 - 現在

出版物

JOURNAL ARTICLE

Bharadwaj, R., Jaiswal, S., Velarde de la Cruz, E.E., Thakare, R.P.(2024). Targeting Solute Carrier Transporters (SLCs) as a Therapeutic Target in Different Cancers . Diseases. 12. (3).

Vollset, S.E., Ababneh, H.S., Abate, Y.H., Abbafati, C., Abbasgholizadeh, R., Abbasian, M., Abbastabar, H., Abd Al Magied, A.H.A., Abd ElHafeez, S., Abdelkader, A., et al.(2024). Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 . The Lancet. 403. (10440). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2204-2256.

Nagar, A., Bharadwaj, R., Shaikh, M.O.F., Roy, A.(2023). What are NLRP3-ASC specks? an experimental progress of 22 years of inflammasome research . Frontiers in Immunology. 14.

Bharadwaj, R., Lusi, C.F., Mashayekh, S., Nagar, A., Subbarao, M., Kane, G.I., Wodzanowski, K.A., Brown, A.R., Okuda, K., Monahan, A., et al.(2023). Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity . Immunity. 56. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 998-1012.e8.

Bharadwaj, R., Anonick, M.V., Jaiswal, S., Mashayekh, S., Brown, A., Wodzanowski, K.A., Okuda, K., Silverman, N., Grimes, C.L.(2023). Synthesis and validation of click-modified NOD1/2 agonists . Innate Immunity. 29. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 186-200.

Gupta, A., Dhiman, A., Sood, A., Bharadwaj, R., Silverman, N., Agrawal, G.(2023). Dextran/eudragit S-100 based redox sensitive nanoparticles for colorectal cancer therapy . Nanoscale. 15. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3273-3283.

Mishra, A.K., Banday, S., Bharadwaj, R., Ali, A., Rashid, R., Kulshreshtha, A., Malonia, S.K.(2023). Macrophages as a Potential Immunotherapeutic Target in Solid Cancers . Vaccines. 11. (1).

Sood, A., Gupta, A., Bharadwaj, R., Ranganath, P., Silverman, N., Agrawal, G.(2022). Biodegradable disulfide crosslinked chitosan/stearic acid nanoparticles for dual drug delivery for colorectal cancer . Carbohydrate Polymers. 294.

Sharma, S., Chanana, P., Bharadwaj, R., Bhattacharya, S., Arya, R.(2022). Functional characterization of GNE mutations prevalent in Asian subjects with GNE myopathy, an ultra-rare neuromuscular disorder . Biochimie. 199. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 36-45.

Ravi Bharadwaj, William A. Petri, Tushar Kushwaha, Azhar Ahmad, Krishna K. Inampudi, Tomoyoshi Nozaki, Somlata(2021). An atypical EhGEF regulates phagocytosis in Entamoeba histolytica through EhRho1 . PLOS Pathogens. 17. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1010030. Public Library of Science ({PLoS})

Ravi Bharadwaj, Alok Bhattacharya, Somlata(2021). Coordinated activity of amoebic formin and profilin are essential for phagocytosis . Molecular Microbiology. 116. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 974--995. Wiley

Bharadwaj, R., Bhattacharya, A., Somlata(2021). Coordinated activity of amoebic formin and profilin are essential for phagocytosis . Molecular Microbiology. 116. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 974-995.

Bharadwaj, R., Kushwaha, T., Ahmad, A., Inampudi, K.K., Nozaki, T., Somlata(2021). An atypical EhGEF regulates phagocytosis in Entamoeba histolytica through EhRho1 . PLoS Pathogens. 17. (11).

Sharma, S., Agarwal, S., Bharadwaj, R., Somlata, Bhattacharya, S., Bhattacharya, A.(2019). Novel regulatory roles of PtdIns(4,5)P₂ generating enzyme EhPIPKI in actin dynamics and phagocytosis of Entamoeba histolytica . Cellular Microbiology. 21. (10).

Singh, S.S., Naiyer, S., Bharadwaj, R., Kumar, A., Singh, Y.P., Ray, A.K., Subbarao, N., Bhattacharya, A., Bhattacharya, S.(2018). Correction: Stress-induced nuclear depletion of Entamoeba histolytica 3-5 exoribonuclease EhRrp6 and its role in growth and erythrophagocytosis(Journal of Biological Chemistry (2018) 293 (16242–16260) Doi: 10.1074/jbc.RA118.004632) . Journal of Biological Chemistry. 293. (50). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 16242.

Singh, S.S., Naiyer, S., Bharadwaj, R., Kumar, A., Singh, Y.P., Ray, A.K., Subbarao, N., Bhattacharya, A., Bhattacharya, S.(2018). Stress-induced nuclear depletion of Entamoeba histolytica 3'-5' exoribonuclease EhRrp6 and its role in growth and erythrophagocytosis . Journal of Biological Chemistry. 293. (42). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 16242-16260.

Bharadwaj, R., Sharma, S., Arya, R., Bhattacharya, S., Bhattacharya, A.(2018). EhRho1 regulates phagocytosis by modulating actin dynamics through EhFormin1 and EhProfilin1 in Entamoeba histolytica . Cellular Microbiology. 20. (9).

Bharadwaj, R., Arya, R., Shahid mansuri, M., Bhattacharya, S., Bhattacharya, A.(2017). EhRho1 regulates plasma membrane blebbing through PI3 kinase in Entamoeba histolytica . Cellular Microbiology. 19. (10).

Mansuri, M.S., Babuta, M., Ali, M.S., Bharadwaj, R., Jhingan, G.D., Gourinath, S., Bhattacharya, S., Bhattacharya, A.(2016). Autophosphorylation at Thr279 of Entamoeba histolytica atypical kinase EhAK1 is required for activity and regulation of erythrophagocytosis . Scientific Reports. 6.

PREPRINT

Ravi Bharadwaj, Madison V. Anonick, Siavash Mashayekh, Ashley Brown, Kimberly A. Wodzanowski, Kendi Okuda, Neal Silverman, Catherine L. Grimes (2023). Synthesis and validation of click-modified of NOD1/2 agonists .

OTHER

Bharadwaj, R., Anonick, M.V., Mashayekh, S., Brown, A., Wodzanowski, K.A., Okuda, K., Silverman, N., Grimes, C.L.(2023). Synthesis and validation of click-modified of NOD1/2 agonists . bioRxiv.

Bharadwaj, R., Lusi, C.F., Mashayekh, S., Nagar, A., Subbarao, M., Kane, G.I., Wodzanowski, K., Brown, A., Okuda, K., Monahan, A., et al.(2022). Methotrexate inhibition of muropeptide transporter SLC46A2 controls psoriatic skin inflammation . bioRxiv.

BOOK CHAPTER

Somlata, Bharadwaj, R., Nozaki, T.(2020). PtdIns(3, 4, 5)P₃ Binding Protein Screening Reveals Unique Molecules Involved in Endocytic Processes . Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology: Overview of the First Eukaryome Congress at Institut Pasteur. Paris, October 16-18, 2019. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 251-262.