プロフィール詳細

プロジェクトを作成

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Dr. Renata P.に依頼

Brazil

Microbiology scientist, expert in medical mycology, drug discovery and insect protein production for food and feed.

プロフィール概要

I am an university professor and scientist with 25 years of experience in various areas of microbiology, genetics and molecular biology. My expertise concentrates in medical mycology, with emphasis in antifungal target identification and validation. My Ph.D. is in genetics and plant breeding and I also worked for pharmaceutical company in biotechnology department as molecular supervisor for recombinant protein production. My ongoing projects are related to drug target identification and antifungal development. More recently, I am developing projects on large scale protein production from insects as a means to provide high quality and sustainable nutrients for food and feed.

専門分野

• ★ Microbiology
• ★ Mycology
• ★ Drug Development
• ☆ Plant Breeding & Genetics
• ☆ Genetics
• ☆ Recombinant Protein Expression
• ☆ Entomology/Insects
• ☆ Composting
• ☆ Pharmaceutical Sciences
• ☆ Sustainable Development

サービス

• Writing
• Research

Writing Technical Writing

Research Fact Checking, Systematic Literature Review

職務経験

Faculty

Universidade Federal de Sao Paulo

2月 2009 - 現在

Molecular Biology Supervisor

Eurofarma Laboratories

6月 2006 - 11月 2008

Research Associate

Duke University Medical Center

10月 2001 - 5月 2004

学歴

Ph.D

Universidade de São Paulo

1月 1995 - 12月 2000

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2020). Biological functions of the autophagy-related proteins Atg4 and Atg8 in Cryptococcus neoformans . PLOS ONE.

(2020). The Third International Symposium on Fungal Stress – ISFUS . Fungal Biology.

(2019). The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases . Scientific Reports.

Martho et al., 2019 .

(2019). First report of cis-1,4-polyisoprene degradation by Gordonia paraffinivorans . Brazilian Journal of Microbiology.

(2019). Characterization of novel hydrocarbon-degrading Gordonia paraffinivorans and Gordonia sihwensis strains isolated from composting . PLOS ONE.

(2019). The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases . Scientific Reports. 9. (1).

Calvete, C. L., Martho, K. F., Felizardo, G., Paes, A., Nunes, J. M., Ferreira, C. O., Vallim, M. A., Pascon, R. C.(2019). Amino acid permeases in Cryptococcus neoformans are required for high temperature growth and virulence; and are regulated by Ras signaling . PLoS One. 14. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e0211393.

Coa, L. L., Abreu, T. F., Tashima, A. K., Green, J., Pascon, R. C., Vallim, M. A., Machado-Jr, J.(2019). AKT/protein kinase B associates with β-actin in the nucleus of melanoma cells . Biosci Rep. 39. (1).

(2017). The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy . PloS one.

et al.(2016). Microbial community structure and dynamics in thermophilic composting viewed through metagenomics and metatranscriptomics . Scientific Reports.

Martho KF, de Melo AT, Takahashi JP, Guerra JM, Santos DC, Purisco SU, Melhem MS, Fazioli RD, Phanord C, Sartorelli P, Vallim MA, Pascon RC, PloS one, 2016, vol. 11, no. 10, pp. e0163919, 2016 .

Santos NO, Mariane B, Lago JH, Sartorelli P, Rosa W, Soares MG, da Silva AM, Lorenzi H, Vallim MA, Pascon RC, Molecules (Basel, Switzerland), 2015, vol. 20, no. 5, pp. 8440-8452 .

Fernandes JD, Martho K, Tofik V, Vallim MA, Pascon RC, PloS one, 2015, vol. 10, no. 7, pp. e0132369 .

de Gontijo FA, Pascon RC, Fernandes L, Machado J Jr, Alspaugh JA, Vallim MA, Fungal genetics and biology : FG & B, 2014, vol. 70, pp. 12-23 .

dos S Grecco S, Dorigueto AC, Landre IM, Soares MG, Martho K, Lima R, Pascon RC, Vallim MA, Capello TM, Romoff P, Sartorelli P, Lago JH, Molecules (Basel, Switzerland), 2014, vol. 19, no. 6, pp. 7528-7542 .

Martins LF, Antunes LP, Pascon RC, de Oliveira JCF, Digiampietri LA, Barbosa D, Peixoto BM, Vallim MA, Viana-Niero C, Ostroski EH, Telles GP, Dias Z, da Cruz JB, Juliano L, Verjovski-Almeida S, da Silva AM, Setubal JC, PLoS ONE, 2013, vol. 8, no. 6 .

Martins LF, Antunes LP, Pascon RC, de Oliveira JC, Digiampietri LA, Barbosa D, Peixoto BM, Vallim MA, Viana-Niero C, Ostroski EH, Telles GP, Dias Z, da Cruz JB, Juliano L, Verjovski-Almeida S, da Silva AM, Setubal JC, PloS one, 2013, vol. 8, no. 4, pp. e61928 .

da Silva EB, Soares MG, Mariane B, Vallim MA, Pascon RC, Sartorelli P, Lago JH, Molecules (Basel, Switzerland), 2013, vol. 18, no. 11, pp. 13574-13587 .

Martins, L.F., Antunes, L.P., Pascon, R.C., De Oliveira, J.C.F., Digiampietri, L.A., Barbosa, D., Peixoto, B.M., Vallim, M.A., Viana-Niero, C., Ostroski, E.H., et al.(2013). Correction: Metagenomic analysis of a tropical composting operation at the São Paulo Zoo Park reveals diversity of biomass degradation functions and organisms (PLoS ONE) . PLoS ONE. 8. (6).

Oliveira LC, Silva VO, Okamoto DN, Kondo MY, Santos SM, Hirata IY, Vallim MA, Pascon RC, Gouvea IE, Juliano MA, Juliano L, Analytical biochemistry, 2012, vol. 421, no. 1, pp. 299-307 .

Pascon RC, Bergamo RF, Spinelli RX, de Souza ED, Assis DM, Juliano L, Vallim MA, Enzyme research, 2011, vol. 2011, pp. 679624 .

Lago JH, Souza ED, Mariane B, Pascon R, Vallim MA, Martins RC, Baroli AA, Carvalho BA, Soares MG, dos Santos RT, Sartorelli P, Molecules (Basel, Switzerland), 2011, vol. 16, no. 12, pp. 9827-9837 .

Bitencourt, A.L.V., Vallim, M.A., Maia, D., Spinelli, R., Angeloni, R., Principal, L., Souza, E., Pascon, R.C.(2010). Core sampling test in large-scale compost cells for microorganism isolation . African Journal of Microbiology Research. 4. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1631-1634.

Sinha H, David L, Pascon RC, Clauder-Münster S, Krishnakumar S, Nguyen M, Shi G, Dean J, Davis RW, Oefner PJ, McCusker JH, Steinmetz LM, Genetics, 2008, vol. 180, no. 3, pp. 1661-1670 .

Pascon RC, Kitajima JP, Breton MC, Assumpção L, Greggio C, Zanca AS, Okura VK, Alegria MC, Camargo ME, Silva GG, Cardozo JC, Vallim MA, Franco SF, Silva VH, Jordão H Jr, Oliveira F, Giachetto PF, Ferrari F, Aguilar-Vildoso CI, Franchiscini FJ, Virus genes, 2006, vol. 32, no. 3, pp. 289-298 .

Pascon RC, Ganous TM, Kingsbury JM, Cox GM, McCusker JH, Microbiology (Reading, England), 2004, vol. 150, no. Pt 9, pp. 3013-3023 .

Semighini CP, von Zeska Kress Fagundes MR, Ferreira JC, Pascon RC, de Souza Goldman MH, Goldman GH, Molecular microbiology, 2003, vol. 48, no. 6, pp. 1693-1709 .

Yang Z, Pascon RC, Alspaugh A, Cox GM, McCusker JH, Microbiology (Reading, England), 2002, vol. 148, no. Pt 8, pp. 2617-2625 .

Yang, Z., Pascon, R.C., Alspaugh, J.A., Cox, G.M., McCusker, J.H.(2002). Molecular and genetic analysis of the Cryptococcus neoformans MET3 gene and a met3 mutant . Microbiology. 148. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2617-2625.

Pascon RC, Miller BL, Molecular microbiology, 2000, vol. 36, no. 6, pp. 1250-1264 .

Fungaro MH, Rech E, Muhlen GS, Vainstein MH, Pascon RC, de Queiroz MV, Pizzirani-Kleiner AA, de Azevedo JL, FEMS microbiology letters, 1995, vol. 125, no. 2-3, pp. 293-297 .