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プロフィール詳細
Dr. Rosario R.に依頼
Spain
Chemist specialized in structural biology, with special interest in computational work and rational drug design.
プロフィール概要
専門分野
サービス
Writing
Technical Writing
Research
Market Research,
Gap Analysis,
Gray Literature Search,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Predictive Modeling,
Data Visualization,
Data Processing
職務経験
PostdoctoralResearcher
CIC bioGUNE
10月 2022 - 現在
Postdoctoral Researcher
CIC bioGUNE
10月 2022 - 現在 
Scientific consultant
Freelance
4月 2017 - 現在
Postdoctoral Researcher
University of Oulu
5月 2019 - 5月 2022
Senior Researcher
Latvian Institute of Organic Synthesis
1月 2014 - 3月 2017
Reseach Associate
Centro Nacional de Biotecnología
1月 2012 - 12月 2013
Reseach Associate
University of Cambridge
7月 2008 - 12月 2011
Reseach Associate
Trinity College Dublin
7月 2004 - 6月 2008
Visitor Scientist
Institut de Génétique et de Biologie Moléculaire et Cellulaire
4月 2003 - 5月 2004
Reseach Associate
European Molecular Biology Organization
3月 2001 - 3月 2003
Reseach Associate
University of Alabama at Birmingham
9月 1997 - 1月 2001
学歴
Doctor (Enginyeria Quimica)
Universitat Politècnica de Catalunya
9月 1992 - 10月 1996
Licenciada (Organic Chemistry)
Universitat de Barcelona
10月 1985 - 3月 1992
認定資格
出版物
JOURNAL ARTICLE
Rosario Recacha, Narasimha Anaganti, Swati Valmiki, Shahidul Islam, Steven Farber, Lloyd Ruddock, M. Mahmood Hussain (2024). Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids . Journal of Biological Chemistry.
Rosario Recacha, Aatir A. Tungekar, Lloyd W. Ruddock (2023). Production of neutralizing antibody fragment variants in the cytoplasm of E. coli for rapid screening: SARS-CoV-2 a case study . Scientific Reports.
Rosario Recacha, Chi Zhang, Lloyd W. Ruddock, Antti Moilanen(2021). Efficient soluble production of folded cat allergen Fel d 1 in Escherichia coli . Protein Expression and Purification. 180. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 105809. Elsevier {BV}
Rosario Recacha, Meredith H. Wilson, Daniel Rader, Sujith Rajan, Aidan Danoff, Richard J. White, Monica R. Hensley, Vanessa H. Quinlivan, James H. Thierer, Frederick J. Tan, et al.(2020). A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein . PLOS Genetics. 16. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1008941. Public Library of Science ({PLoS})
(2020). A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein . PLOS Genetics.
Santiago C, Mudgal G, Reguera J, Recacha R, Albrecht S, Enjuanes L, Casasnovas JM(2017). Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection . Scientific reports.
Recacha R, Jaudzems K, Akopjana I, Jirgensons A, Tars K(2016). Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins . Acta crystallographica. Section F, Structural biology communications.
Rasina D, Otikovs M, Leitans J, Recacha R, Borysov OV, Kanepe-Lapsa I, Domraceva I, Pantelejevs T, Tars K, Blackman MJ, et al.(2015). Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV . Journal of medicinal chemistry.
Recacha R, Leitans J, Akopjana I, Aprupe L, Trapencieris P, Jaudzems K, Jirgensons A, Tars K(2015). Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors . Acta crystallographica. Section F, Structural biology communications.
Recacha R, Jiménez D, Tian L, Barredo R, Gahmberg CG, Casasnovas JM(2014). Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions . Acta Crystallographica Section D: Biological Crystallography.
Fernandes H, Franklin E, Recacha R, Houdusse A, Goud B, Khan AR(2009). Structural aspects of Rab6-effector complexes . Biochemical Society transactions.
Recacha R, Boulet A, Jollivet F, Monier S, Houdusse A, Goud B, Khan AR(2009). Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain . Structure (London, England : 1993).
Costanzo MJ, Yabut SC, Almond HR, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, et al.(2003). Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone . Journal of medicinal chemistry.
Greco MN, Hawkins MJ, Powell ET, Almond HR, Corcoran TW, de Garavilla L, Kauffman JA, Recacha R, Chattopadhyay D, Andrade-Gordon P, et al.(2002). Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design . Journal of the American Chemical Society.
Recacha R, Costanzo MJ, Maryanoff BE, Chattopadhyay D(2002). Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate . The Biochemical journal.
Recacha R, Costanzo MJ, Maryanoff BE, Carson M, DeLucas L, Chattopadhyay D(2000). Structure of human alpha-thrombin complexed with RWJ-51438 at 1.7 A: unusual perturbation of the 60A-60I insertion loop . Acta Crystallographica Section D: Biological Crystallography.
Chattopadhyay D, Langsley G, Carson M, Recacha R, DeLucas L, Smith C(2000). Structure of the nucleotide-binding domain of Plasmodium falciparum rab6 in the GDP-bound form . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Talalaev A, DeLucas LJ, Chattopadhyay D(2000). Toxoplasma gondii adenosine kinase: expression, purification, characterization, crystallization and preliminary crystallographic analysis . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Carson M, Costanzo MJ, Maryanoff B, DeLucas LJ, Chattopadhyay D(1999). Structure of the RWJ-51084-bovine pancreatic beta-trypsin complex at 1.8 A . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Verdaguer N, Subirana JA(1997). Structure and supramolecular packing features of the dipeptide Arg-Val acetate . The journal of peptide research : official journal of the American Peptide Society.
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