プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Rudra M.に依頼

India

Integrated Wet Lab & Computational Drug Discovery Scientist | AMPs, Molecular Modeling, AMR & Manuscript Writing

プロフィール概要

I am a biotechnology researcher with integrated expertise in wet-lab experimentation and computational drug discovery, specializing in antimicrobial peptides (AMPs) and antimicrobial resistance (AMR). My work focuses on the design, synthesis, and evaluation of peptide-based therapeutics and peptide–antibiotic conjugates targeting drug-resistant pathogens, particularly Staphylococcus aureus. I have hands-on experience in microbiological assays, biofilm studies, membrane permeability analysis, protein and peptide characterization, conjugation strategies and cell culture studies. Alongside experimental work, I provide computational services including molecular docking, molecular dynamics simulations, density functional theory (DFT) analysis, interaction profiling, and structure-based drug design. I also work on polymer–ligand interactions, hydrogel-based delivery systems, and phytochemical screening for antimicrobial applications. My ongoing and previous research projects include the development of novel AMP–antibiotic conjugates, plant-derived antimicrobial peptide discovery, computational screening of therapeutic compounds, and integrated in silico–in vitro validation workflows. I also have experience building automated pipelines for docking, interaction analysis, and computational chemistry workflows. In addition to research, I offer scientific manuscript writing, editing, figure preparation, thesis support, and grant proposal development. I am experienced in preparing publication-ready data, statistical analysis, and visualization for high-quality scientific reports. I hold advanced training in biotechnology and drug discovery, with a strong focus on translational research aimed at bridging computational predictions with experimental validation. I am committed to delivering reliable, well-documented, and client-oriented research solutions for academic, biotech, and pharmaceutical projects.

専門分野

• ☆ Molecular Modeling
• ☆ Molecular Docking
• ☆ Flow Chemistry
• ☆ Computational Chemistry
• ☆ Computational Biology
• ☆ Evolutionary Biology
• ☆ Microbiology
• ☆ Microbiome Research
• ☆ Mycology/Fungi
• ☆ Industrial Microbiology
• ☆ Microbiological Assays
• ☆ Bacteriology
• ☆ Gram-Negative Bacteria
• ☆ Gram-Positive Bacteria
• ☆ Agricultural Microbiology
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Omics
• ☆ Transcriptomics
• ☆ Comparative Genomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ Genomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Protein Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Nanobiotechnology
• ☆ Microbial Biotechnology
• ☆ Biomimetics
• ☆ Bioprinting
• ☆ Statistics
• ☆ Pathogenesis
• ☆ Clinical Microbiology
• ☆ Microbial Fermentation
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ R
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Drug Design
• ☆ Combinatorial Chemistry
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Drug Formulation
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Biosafety Testing
• ☆ Microbiology Testing
• ☆ Solid Form Screening
• ☆ Bioanalytical Testing
• ☆ Drug Stability Testing
• ☆ In vitro Preclinical Toxciology
• ☆ Hypothesis
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Creative Writing, General Proofreading & Editing, Translation

Research Market Research, User Research, Meta-Research, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Business Strategy Consulting, Go-to-Market Strategy Consulting, Digital Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

Product Development Formulation, Stability/Shelf Life Testing, Product Evaluation, Material Sourcing, Product Validation, Quality Assurance & Control (QA/QC), Concept Development, Prototyping

職務経験

Founder, Director

Spatial Biologics

10月 2024 - 現在

PhD Scholar

VIT University

9月 2020 - 3月 2024

学歴

PhD in Biotechnology

Vellore Institute of Technology

9月 2020 - 1月 2026

M. Tech

SRM Institute Of Science & Technology ( Deemed University) - India

6月 2018 - 6月 2020

認定資格

• Training Program

  Department of Crystallography, University of Madras

  1月 2017 - 2月 2017

出版物

JOURNAL ARTICLE

Verma, T., Mishra, R.A.K., Easwaran, N., Muthukaliannan, G.K.(2024). Analyzing the Immunomodulatory Effects of Tea PolyPhenols and in management of COVID-19 . Current Trends in Biotechnology and Pharmacy. 18. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1999-2014.

Ramalingam, P.S., Italiya, G., Elangovan, S., Mishra, R.A.K., Aranganathan, M., Rajangam, E., Sukumar, N., Patel, B.Y., Janaki Ramaiah, M., Subramanian, S., et al.(2024). Computational identification and experimental validation of potential inhibitors of JAK1 kinase from natural source for the effective treatment of colorectal adenocarcinoma . South African Journal of Botany. 171. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 412-424.

Awdhesh Kumar Mishra, R., Kodiveri Muthukaliannan, G.(2024). In-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus . Scientific Reports. 14. (1).

Ramani, N., Patel, B.Y., Italiya, G., Ramalingam, P.S., Mishra, R., Subramanian, S., Hadiyal, S.D.(2024). Synthesis of 8-methyl-2-phenylquinazolin-4(3H)-ones derived Schiff's bases: Spectroscopic properties, SAR, docking approaches and their anticancer and antimicrobial activity . Journal of Molecular Structure. 1310.

Mishra, R.A.K., Thorat, R.V., Mahapatra, S., Dash, S.P., Dharmaji, S.L., Easwaran, N., Jayaraj, R., Muthukaliannan, G.K.(2023). Analyzing the Active Constituents of Astragalus: A Salient Element in Human Health . Current Trends in Biotechnology and Pharmacy. 17. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1327-1339.

Mishra, R.A.K., Muthukaliannan, G.K., Rathinasabapathi, P.(2023). Effects of Flavonoids and Antibiotics Combination on Preformed Biofilms and Small RNA of Staphylococcus aureus . Indian Journal of Microbiology. 63. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 307-316.

Awdhesh Kumar Mishra, R., Kodiveri Muthukaliannan, G.(2022). Role of microalgal metabolites in controlling quorum-sensing-regulated biofilm . Archives of Microbiology. 204. (3).

Mishra, R., Rathinasabapathi, P.(2020). Antibiotics susceptibility profile and synergistic effects of flavonoids with antibiotics against resistant staphylococcus aureus from asymptomatic individuals . Journal of Pure and Applied Microbiology. 14. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2669-2676.

BOOK CHAPTER

Ramalingam, P.S., Mishra, R.A.K., Mekala, J.R., Gothandam, K.M., Arumugam, S.(2023). Nigella Sativa L.-A note on phytochemistry, extraction, pharmacological activities, and therapeutic utility . Pharmacological Aspects of Essential Oils Current and Future Trends. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 243-264.