プロフィール詳細

プロジェクトを作成

★★★★★

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★★★★★

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Russell K.に依頼

Czech Republic

Senior Organic Chemist | Structure Elucidation & Complex NMR Analysis | Synthetic Chemistry

プロフィール概要

Senior Organic Chemist and Associate Professor with 17 years of dual academic-industrial experience in medicinal chemistry and drug discovery. Core Expertise Includes: - Structure Elucidation: Advanced interpretation of complex, ambiguous, or multi-component 1D/2D NMR data sets. - Synthetic Chemistry: Route design, optimization, and troubleshooting for small-molecule therapeutics and intermediates. - Technical Writing: Preparing peer-reviewed manuscripts, structural reports, and technical documentation to publication-ready standards, with a specialization in complex data curation and presentation.

専門分野

• ☆ Natural Product Chemistry
• ☆ Analytical Chemistry
• ☆ Spectroscopy
• ☆ NMR Spectroscopy
• ☆ Organic Chemistry
• ☆ Retrosynthesis

サービス

• Writing
• Consulting
• Data & AI
• Product Development

Writing General Proofreading & Editing

Consulting Scientific and Technical Consulting

Data & AI Data Processing, Data Insights

Product Development Concept Development

職務経験

Associate Professor (docent), Researcher, Lecturer

Charles University

1月 2023 - 現在

Associate Professor, Director of Education

University of Warwick

11月 2015 - 12月 2022

Lecturer/ Teaching Fellow

The University of Nottingham

10月 2014 - 11月 2015

Postdoctoral Researcher

The University of Nottingham

10月 2010 - 10月 2014

Senior Research Chemist

Sygnature Chemical Services (now Sygnature Discovery)

5月 2010 - 9月 2010

学歴

Chemistry PhD

The University of York

10月 2006 - 5月 2010

MChem

The University of Leeds

10月 2002 - 6月 2006

認定資格

• Senior Fellow of the Higher Education Academy (SFHEA)

  Higher Education Academy, UK

  1月 2026 - 現在

出版物

JOURNAL ARTICLE

Hiroyuki Oshikiri, Keiko Taguchi, Wataru Hirose, Yusuke Taniyama, Takashi Kamei, David Siegel, David Ross, Russell R. A. Kitson, Liam Baird, Masayuki Yamamoto (2025). Anticancer Effect of C19-Position Substituted Geldanamycin Derivatives Targeting NRF2-NQO1-activated Esophageal Squamous Cell Carcinoma . Molecular and Cellular Biology.

Finger, V., Kucera, T., Kafkova, R., Muckova, L., Dolezal, R., Kubes, J., Novak, M., Prchal, L., Lakatos, L., Andrs, M., et al.(2023). 2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1 . European Journal of Medicinal Chemistry. 258.

Racheal Greaves, Bozhena Kelestyn, Richard A. R. Blackburn, Russell R. A. Kitson(2022). The Black Student Experience: Comparing STEM Undergraduate Student Experiences at Higher Education Institutions of Varying Student Demographic . Journal of Chemical Education. American Chemical Society ({ACS})

Hill, M.A., Overton, T., Kitson, R.R.A., Thompson, C.D., Brookes, R.H., Coppo, P., Bayley, L.(2022). ‘They help us realise what we’re actually gaining’: The impact on undergraduates and teaching staff of displaying transferable skills badges . Active Learning in Higher Education. 23. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 17-34.

Pearson, D.L., Kitson, R.R.A.(2022). Quinone Synthesis and a Visual Introduction to Column Chromatography: An Undergraduate Experiment . Journal of Chemical Education. 99. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3731-3734.

Greaves, R., Kelestyn, B., Blackburn, R.A.R., Kitson, R.R.A.(2022). The Black Student Experience: Comparing STEM Undergraduate Student Experiences at Higher Education Institutions of Varying Student Demographic . Journal of Chemical Education. 99. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 56-70.

Russell R.A. Kitson, Christopher J. Moody (2021). Synthesis of novel geldanamycin derivatives . Tetrahedron.

Kitson, R.R.A., Moody, C.J.(2021). Synthesis of novel geldanamycin derivatives . Tetrahedron. 82.

George-Williams, S.R., Karis, D., Ziebell, A.L., Kitson, R.R.A., Coppo, P., Schmid, S., Thompson, C.D., Overton, T.L.(2019). Correction: Investigating student and staff perceptions of students' experiences in teaching laboratories through the lens of meaningful learning (Chemistry Education Research and Practice (2019) DOI: 10.1039/c8rp00188j) . Chemistry Education Research and Practice. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 329.

Stephen R. George-Williams, Dimitri Karis, Angela L. Ziebell, Russell R. A. Kitson, Paolo Coppo, Siegbert Schmid, Christopher D. Thompson, Tina L. Overton(2019). Investigating student and staff perceptions of students' experiences in teaching laboratories through the lens of meaningful learning . Chemistry Education Research and Practice. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 187--196. Royal Society of Chemistry ({RSC})

George-Williams, S.R., Karis, D., Ziebell, A.L., Kitson, R.R.A., Coppo, P., Schmid, S., Thompson, C.D., Overton, T.L.(2019). Investigating student and staff perceptions of students' experiences in teaching laboratories through the lens of meaningful learning . Chemistry Education Research and Practice. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 187-196.

Michelle A. Hill, Tina L. Overton, Christopher D. Thompson, Russell R. A. Kitson, Paolo Coppo(2019). Undergraduate recognition of curriculum-related skill development and the skills employers are seeking . Chemistry Education Research and Practice. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 68--84. Royal Society of Chemistry ({RSC})

Hill, M.A., Overton, T.L., Thompson, C.D., Kitson, R.R.A., Coppo, P.(2019). Undergraduate recognition of curriculum-related skill development and the skills employers are seeking . Chemistry Education Research and Practice. 20. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 68-84.

Stephen R. George-Williams, Angela L. Ziebell, Russell R. A. Kitson, Paolo Coppo, Christopher D. Thompson, Tina L. Overton(2018). ‘What do you think the aims of doing a practical chemistry course are?’ A comparison of the views of students and teaching staff across three universities . Chemistry Education Research and Practice. 19. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 463--473. Royal Society of Chemistry ({RSC})

George-Williams, S.R., Ziebell, A.L., Kitson, R.R.A., Coppo, P., Thompson, C.D., Overton, T.L.(2018). 'What do you think the aims of doing a practical chemistry course are?' A comparison of the views of students and teaching staff across three universities . Chemistry Education Research and Practice. 19. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 463-473.

David, N., Pasceri, R., Kitson, R.R.A., Pradal, A., Moody, C.J.(2016). Back Cover: Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement (Chem. Eur. J. 31/2016) . Chemistry - A European Journal. 22. (31). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11088.

David, N., Pasceri, R., Kitson, R.R.A., Pradal, A., Moody, C.J.(2016). Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement . Chemistry - A European Journal. 22. (31). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 10867-10876.

Xiong, R., Zhou, W., Siegel, D., Kitson, R.R.A., Freed, C.R., Moody, C.J., Ross, D.(2015). A novel Hsp90 inhibitor activates compensatory heat shock protein responses and autophagy and alleviates mutant A53T α-synuclein toxicity . Molecular Pharmacology. 88. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1045-1054.

Chang, C.-H., Drechsel, D.A., Kitson, R.R.A., Siegel, D., You, Q., Backos, D.S., Ju, C., Moody, C.J., Ross, D.(2014). 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: Biological activity and decreased off-target toxicity . Molecular Pharmacology. 85. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 849-857.

Anderson, I., Low, J.S., Weston, S., Weinberger, M., Zhyvoloup, A., Labokha, A.A., Corazza, G., Kitson, R.A., Moody, C.J., Marcello, A., et al.(2014). Heat shock protein 90 controls HIV-1 reactivation from latency . Proceedings of the National Academy of Sciences of the United States of America. 111. (15).

Dutton, B.L., Kitson, R.R.A., Parry-Morris, S., Roe, S.M., Prodromou, C., Moody, C.J.(2014). Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90 . Organic and Biomolecular Chemistry. 12. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1328-1340.

Giallombardo, D., Nevin, A.C., Lewis, W., Nawrat, C.C., Kitson, R.R.A., Moody, C.J.(2014). Synthesis of toxyloxanthone B . Tetrahedron. 70. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1283-1288.

Nawrat, C.C., Kitson, R.R.A., Moody, C.J.(2014). Toward the total synthesis of hygrocin B and divergolide C: Construction of the naphthoquinone-azepinone core . Organic Letters. 16. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1896-1899.

Kitson, R.R.A., Moody, C.J.(2013). An improved route to 19-substituted geldanamycins as novel Hsp90 inhibitors – potential therapeutics in cancer and neurodegeneration . Chemical Communications. 49. (76). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8441-8443.

Kitson, R.R.A., Moody, C.J.(2013). Learning from nature: Advances in geldanamycin- and radicicol-based inhibitors of Hsp90 . Journal of Organic Chemistry. 78. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5117-5141.

Kitson, R.R.A., Chang, C.-H., Xiong, R., Williams, H.E.L., Davis, A.L., Lewis, W., Dehn, D.L., Siegel, D., Roe, S.M., Prodromou, C., et al.(2013). Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90 . Nature Chemistry. 5. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 307-314.

Kitson, R.R.A., McAllister, G.D., Taylor, R.J.K.(2011). Synthesis of yomogin using a telescoped α-methylene-γ- butyrolactone annelation procedure . Tetrahedron Letters. 52. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 561-564.

Kitson, R.R.A., Taylor, R.J.K., Wood, J.L.(2009). A one-pot, base-free annelation approach to α-alkylidene- γbutyrolactones . Organic Letters. 11. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5338-5341.

Kitson, R.R.A., Millemaggi, A., Taylor, R.J.K.(2009). The renaissance of α-methylene-γ-butyrolactones: new synthetic approaches . Angewandte Chemie - International Edition. 48. (50). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9426-9451.

Edwards, M.G., Kenworthy, M.N., Kitson, R.R.A., Perry, A., Scott, M.S., Whitwood, A.C., Taylor, R.J.K.(2008). The preparation of α-alkylidene-γ-butyrolactones using a telescoped intramolecular Michael/Olefination (TIMO) sequence: Synthesis of (+)-paeonilactone B . European Journal of Organic Chemistry. (28). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4769-4783.

Edwards, M.G., Kenworthy, M.N., Kitson, R.R.A., Scott, M.S., Taylor, R.J.K.(2008). The telescoped intramolecular Michael/olefination (TIMO) approach to α-alkylidene-γ-butyrolactones: Synthesis of (+)-paeonilactone B . Angewandte Chemie - International Edition. 47. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1935-1937.

OTHER

Finger, V., Kucera, T., Kafkova, R., Muckova, L., Dolezal, R., Kubes, J., Novak, M., Prchal, L., Lakatos, L., Andrs, M., et al.(2023). 2,6-Disubstituted 7-(Naphthalen-2-Ylmethyl)-7h-Purines as a New Class of Potent Antitubercular Agents Inhibiting Dpre1 . SSRN.

BOOK

Ramsey, D.M., Kitson, R.R.A., Levin, J.I., Moody, C.J., McAlpine, S.R.(2015). Recent advances in macrocyclic Hsp90 inhibitors . RSC Drug Discovery Series. 2015-January. (40). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 37-77.