プロフィール詳細

プロジェクトを作成

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Sara A.に依頼

Colombia

Director of Preclinical & Translational studies / Non-Clinical Pharmacology / Project Manager / Medical Research

プロフィール概要

Experienced scientific leader with over a decade of expertise in the design, execution, and management of preclinical and translational studies for drug development. Demonstrated expertise leading diverse projects across all stages of non-clinical development, spanning proof-of-concept, mechanisms of action, identifying biomarkers, non-clinical pharmacology, toxicology, and safety studies, with hands-on expertise in a wide range of laboratory techniques, and demonstrated expertise in designing and conducting complex in-vivo and in-vitro experiments, with deep understanding of animal welfare, ethical standards, and regulatory frameworks. Proficient in translating intricate scientific concepts and experimental data into actionable insights for clinical development. Proven track record of cross-functional team leadership, technical staff training, and stakeholder collaboration. Accomplished communicator with a robust publication record, and experience mentoring scientific talent.

専門分野

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Neuroscience
• ☆ Neurophysiology
• ☆ Neuropharmacology
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Biomarker Discovery
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Veterinary Medicine
• ☆ Veterinary Pathology
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Medical Imaging/Radiology
• ☆ Human Biology
• ☆ Endocrinology
• ☆ Diabetes
• ☆ Medical X-Ray
• ☆ Electrocardiogram (ECG)
• ☆ Ultrasound
• ☆ Diagnostic Radiology
• ☆ Traditional Medicine
• ☆ Psychoactive Drugs
• ☆ Internal Medicine
• ☆ Zoonoses
• ☆ Medical Sciences
• ☆ Metabolism & Metabolic Disease

サービス

• Writing

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

職務経験

Head of In-vivo research

Neuro-Sys

9月 2024 - 3月 2025

Director of Preclinical Studies

Carvin medicines

11月 2021 - 4月 2024

Postdoctoral Researcher

Tel Aviv University

10月 2018 - 5月 2022

Principal Lecturer

Universidad del Valle de Mexico - UVM

8月 2017 - 12月 2018

Invited Researcher

University of Barcelona

2月 2018 - 7月 2018

Professor's assistant

Universidad Nacional Autonoma de México

1月 2013 - 1月 2017

学歴

Doctor of Science

Universidad Nacional Autónoma de México - UNAM

8月 2014 - 7月 2018

M.Sc (Master of Science)

Universidad Nacional Autónoma de México - UNAM

8月 2012 - 7月 2014

Doctor of Veterinary Medicine

Universidad Nacional de Colombia

8月 2003 - 12月 2009

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Sara Arciniegas Ruiz, Ido Rippin, Hagit Eldar-Finkelman(2022). Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy . Cells. 11. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1618. {MDPI} {AG}

Sara Melisa Arciniegas Ruiz, Ido Rippin, Hagit Eldar-Finkelman (2022). Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy . Cells.

Ido Rippin, Netaly Khazanov, Shirley Ben Joseph, Tania Kudinov, Eva Berent, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Laura Levy, Arie Gruzman, Hanoch Senderowitz, et al.(2020). Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site . International Journal of Molecular Sciences. 21. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8709. {MDPI} {AG}

Ido Rippin, Netaly Khazanov, Shirley Ben Joseph, Tania Kudinov, Eva Berent, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Laura Levy, Arie Gruzman, Hanoch Senderowitz, et al. (2020). Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site . International Journal of Molecular Sciences.

Sara Melisa Arciniegas Ruiz, Lilia Gutiérrez Olvera, Sara del Carmen Caballero Chacón, Dinorah Vargas Estrada(2015). Pharmacokinetics of an oral extended-release formulation of doxycycline hyclate containing acrylic acid and polymethacrylate in dogs . American Journal of Veterinary Research. 76. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 367--372. American Veterinary Medical Association ({AVMA})

Sara Melisa Arciniegas Ruiz, Lilia Gutiérrez Olvera, María Josefa Bernad Bernad, Sara del Carmen Caballero Chacón, Dinorah Vargas Estrada(2015). Comparative pharmacokinetics of a new oral long-acting formulation of doxycycline hyclate: A canine clinical trial . European Journal of Pharmaceutical Sciences. 80. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9--15. Elsevier {BV}