プロフィール詳細

プロジェクトを作成

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Shaokun L.に依頼

Germany

Medical Writer & Researcher | Systematic Reviews, Clinical Data Analysis, Regulatory Docs | PhD, Charité Berlin

プロフィール概要

I am a PhD candidate in Otolaryngology / Head and Neck Surgery at Charité – Universitätsmedizin Berlin, one of Europe's leading academic medical centers. My research focuses on head and neck squamous cell carcinoma (HNSCC), integrating patient-derived tumor organoids (PDOs), single-cell and spatial transcriptomics, and multi-omics analysis to investigate tumor immune microenvironment remodeling and treatment resistance mechanisms. Medical Writing & Systematic Reviews I have authored 7 first-author peer-reviewed publications across journals including The Lancet Oncology, Oncology Research, Environmental Toxicology, Journal of Applied Genetics, BMC Medical Genomics, and Discover Oncology. My writing portfolio spans original research articles, systematic reviews, and clinical correspondence. I serve as a peer reviewer for Discover Oncology and Scientific Reports, with experience evaluating manuscripts across oncology, genomics, and translational medicine. Clinical & Bioinformatics Data Analysis I have hands-on expertise in single-cell RNA sequencing (scRNA-seq), bulk transcriptomics, multi-omics integration (genomic, epigenomic, transcriptomic, proteomic, and metabolomic data), and tumor microenvironment deconvolution. I am proficient in R and Python-based bioinformatics pipelines and have applied these skills across multiple published projects involving HNSCC, laryngeal cancer, and colorectal cancer datasets. Regulatory & Scientific Documents With a clinical medicine background (Bachelor's, Wuhan University of Science and Technology; Master's, Capital Medical University / Xuanwu Hospital), I bring both bench and bedside perspectives to scientific and regulatory documentation. I am experienced in drafting structured scientific reports, grant-supporting materials, and research protocols aligned with translational and clinical research standards. I am available for projects involving systematic literature reviews, medical writing (manuscripts, reviews, regulatory summaries), clinical data analysis, and bioinformatics consulting. I am committed to delivering rigorous, publication-ready work on schedule.

専門分野

• ☆ Biostatistics
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Clinical Trials
• ☆ Clinical Trials Data Analysis
• ☆ Oncology

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Translation

Research Meta-Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Analysis, Data Visualization, Data Cleaning, Data Processing, Data Insights

職務経験

PhD student

Charité - Universitätsmedizin Berlin

- 現在

Doctor

Xuanwu Hospital Capital Medical University

8月 2020 - 8月 2024

学歴

PhD

Charité Universitätsmedizin Berlin

9月 2024 - 現在

PhD

Charité - Universitätsmedizin Berlin

2024 - 現在

Master

Capital Medical University

2020 - 2023

Bachelor

Wuhan University of Science and Technology

9月 2015 - 6月 2020

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Shaokun Liu, Shiqian Liu, Matthäus Felsenstein, Igor Maximilian Sauer, Muhammad Imtiaz Ashraf (2026). Targeting the stromal-immune barrier: A novel strategy to overcome resistance to CLDN18.2/CD3 bispecific T-cell engager therapy in pancreatic cancer . Cancer Letters.

Shaokun Liu, Anna Maria Pfefferkorn, Raphaela Fritsche-Guenther, Angelika Kusch, Hubert Schwelberger, Shiqian Liu, Robert Klopfleisch, Yuhuan Li, Rusan Catar, Felix Aigner, et al. (2025). Lipocalin-2 modulates recipients alloimmune responses to the murine kidney transplants . Frontiers in Immunology.

Shaokun Liu, Boxuan Han, Ridhima Das, Shiqian Liu, Yang Zhang (2025). Organoid Technology in Precision Medicine for Head and Neck Cancer . Oncology Research.

Shaokun Liu, Boxuan Han, Shiqian Liu (2025). AJCC9V classification for HPV-positive oropharyngeal carcinoma . The Lancet Oncology.

Han, B., & Liu, S. (2025). Sphingomyelin mediates the association between natural killer cell receptor 2B4 (CD244) and head and neck cancer. Life Conflux, 1(2), e145. https://doi.org/10.71321/cdx1k098 .

Shaokun Liu, Meng Lian, Boxuan Han, Jugao Fang, Zhenlin Wang (2024). Single-cell integrated transcriptomics reveals the role of keratinocytes in head and neck squamous cell carcinoma . Journal of Applied Genetics.

Shaokun Liu, Boxuan Han, Ru Wang, Jugao Fang (2024). Elucidating the role of FOS in modulating the immune microenvironment through fibroblast and myeloid cell regulation in locoregional recurrent HNSCC . Environmental Toxicology.

Shaokun Liu, Ru Wang, Jugao Fang (2024). Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma . Discover Oncology.

Liu, S., Han, B., Wang, R., Fang, J.(2024). Elucidating the role of FOS in modulating the immune microenvironment through fibroblast and myeloid cell regulation in locoregional recurrent HNSCC . Environmental Toxicology.

Liu, S., Wang, R., Fang, J.(2024). Exploring the frontiers: tumor immune microenvironment and immunotherapy in head and neck squamous cell carcinoma . Discover Oncology. 15. (1).

Liu, S., Lian, M., Han, B., Fang, J., Wang, Z.(2024). Single-cell integrated transcriptomics reveals the role of keratinocytes in head and neck squamous cell carcinoma . Journal of Applied Genetics.

He, S., He, Y., Zhu, S., Wang, R., Liu, S., Wang, L., Shen, X., Li, X., Chen, S., Fang, J.(2024). M2 Macrophage exosomal HOXC13-AS in laryngeal cancer immunity via targeting miR-485-5p/IGF2BP2/PD-L1 . International Immunopharmacology. 140.

Han, B., Sun, M., Zhao, Y., Baranova, A., Cao, H., Liu, S., Shen, X., Hou, L., Fang, J., Lian, M.(2024). Genetic predisposition to milder forms of COVID-19 may provide some resilience to head and neck cancers . Frontiers in Oncology. 14.

Shaokun Liu, Shuning Wang, Zhenlin Wang(2023). Identification of genetic mechanisms underlying lipid metabolism-mediated tumor immunity in head and neck squamous cell carcinoma . BMC Medical Genomics. 16. (1). Springer Science and Business Media {LLC}

Liu, S., Wang, S., Wang, Z.(2023). Identification of genetic mechanisms underlying lipid metabolism-mediated tumor immunity in head and neck squamous cell carcinoma . BMC Medical Genomics. 16. (1).

Hou, S., Li, X., Meng, F., Liu, S., Wang, Z.(2023). A Machine Learning–Based Prediction of Diabetes Insipidus in Patients Undergoing Endoscopic Transsphenoidal Surgery for Pituitary Adenoma . World Neurosurgery. 175. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e55-e63.

Shaokun Liu, Zhenlin Wang, Simin Li(2022). Interferon Regulatory Factor Family Genes: At the Crossroads between Immunity and Head and Neck Squamous Carcinoma . Disease Markers. 2022. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--19. Hindawi Limited

Liu, S., Wang, Z.(2022). Interferon Regulatory Factor Family Genes: At the Crossroads between Immunity and Head and Neck Squamous Carcinoma . Disease Markers. 2022.