プロフィール詳細

プロジェクトを作成

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Dr. Shilpa P.に依頼

India

Expert in cancer biology, Genetics, Biochemistry and Immunology, proficiency in scientific writing and literature review

プロフィール概要

Researcher with the expertise in cancer biology and a strong background of Genetics, Biochemistry and immunology. -My postdoctoral work was mainly associated with Radiation oncology where I studied mechanisms of radiation-induced normal tissue injury and its association with tumor growth and metastasis. We used mouse models to screen several drugs which can be used in combination therapy to protect from radiation injury. -My doctoral work was centered around a protein called IGFBP2. I studied several mechanisms of this protein by which it increases aggressiveness of a grade IV brain tumor (GBM). I also screened and purified a human single chain variable fragment (ScFV) that neutralizes the protumorigenic actions of IGFBP2 protein and hence has a potential therapeutic value. - Served as author on eight peer reviewed publications -was a speaker in departmental seminars as well as national and international conferences, delivering oral presentations as well as poster presentations -Mentored school teachers on basics in cancer biology, have guided students during their summer internship, shared experiences with juniors about best lab practices and troubleshooting experiments, helped students working in interdisciplinary programmes -Effectively collaborated with Pathologists and Technicians at a professional level to carry out the research work

専門分野

• ★ Biochemistry
• ★ Molecular Biology
• ★ Cancer Research

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Technical Writing, Copywriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

Product Development Formulation

職務経験

Postdoctoral research fellow

NCI, National Institutes of Health (NIH), Bethesda, USA

7月 2016 - 3月 2019

DBT-RA- Postdoctoral research fellow

NIMHANS, Bangalore, India

1月 2016 - 5月 2016

学歴

PhD, Oncology and Cancer biology

Indian Institute of Science, Bangalore, India

6月 2009 - 12月 2015

MSc, Masters in microbiology

University of Pune, Pune, India

6月 2007 - 6月 2009

B. Sc. in Microbiology, Genetics and Immunology

H.P.T. Arts and R.Y.K. Science college, Nashik, India

6月 2004 - 6月 2007

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2019). 12-Lipoxygenase is a Critical Mediator of Type II Pneumocyte Senescence, Macrophage Polarization and Pulmonary Fibrosis after Irradiation . Radiation research.

(2017). Mithramycin A Enhances Tumor Sensitivity to Mitotic Catastrophe Resulting From DNA Damage . International journal of radiation oncology, biology, physics.

(2016). Insulin-like growth factor binding protein-2 regulates β-catenin signaling pathway in glioma cells and contributes to poor patient prognosis . Neuro-oncology.

(2015). Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion . Journal of neuro-oncology.

(2015). Protamine-carboxymethyl cellulose magnetic nanocapsules for enhanced delivery of anticancer drugs against drug resistant cancers . Nanomedicine : nanotechnology, biology, and medicine.

(2014). 2-(Phenylazo)pyridineplatinum(II) catecholates showing photocytotoxicity, nuclear uptake, and glutathione-triggered ligand release . Inorganic chemistry.

(2014). Insulin like growth factor binding protein 4 promotes GBM progression and regulates key factors involved in EMT and invasion . Journal of neuro-oncology.

(2013). Regulation of protumorigenic pathways by insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis . Molecular cancer.