プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. Silvia G.に依頼

Finland

Cellular and Molecular biology, cancer research and virology expert, data analysis and visualization, writing&editing.

プロフィール概要

My current projects aim to elucidate the role of transcription factors in different types of oncogenesis and molecular mechanisms of melanoma metastasis. During my PhD I studied the oncogenic properties of viral proteins. I have a vast bench experience in molecular and cellular biology, I can set up/troubleshoot experiments, help with data visualization, writing and editing.

専門分野

• ★ Cancer Research
• ☆ Virology
• ☆ Cytomegaloviruses
• ☆ Molecular Biology
• ☆ Data Analysis
• ☆ Data Visualization
• ☆ Infectious Disease
• ☆ Viral Diseases

サービス

• Writing
• Research
• Data & AI

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting

Research Feasibility Study, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Data Visualization

職務経験

Post doctoral researcher

University of Helsinki

10月 2015 - 現在

post-doctoral researcher

University of Helsinki

10月 2015 - 現在

学歴

PhD (Virology)

Hannover Medical School

10月 2011 - 9月 2015

PhD

Hannover Medical School, Hannover, Germany

10月 2011 - 7月 2015

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Endrit Elbasani and Francesca Falasco and Silvia Gramolelli and Veijo Nurminen and Thomas Günther and Jere Weltner and Diego Balboa and Adam Grundhoff and Timo Otonkoski and Päivi M. Ojala(2020). Kaposi’s Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter . Viruses. 12. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 952. {MDPI} {AG}

Silvia Gramolelli and Endrit Elbasani and Krista Tuohinto and Veijo Nurminen and Thomas Günther and Riikka E. Kallinen and Seppo P. Kaijalainen and Raquel Diaz and Adam Grundhoff and Caj Haglund and Joseph M. Ziegelbauer and Teijo Pellinen and Mark Bower and Mathias Francois and Päivi M. Ojala(2020). Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production . Cancer Research. 80. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3116--3129. American Association for Cancer Research ({AACR})

Endrit Elbasani and Silvia Gramolelli and Thomas Günther and Ildar Gabaev and Adam Grundhoff and Päivi M. Ojala(2020). Kaposi’s Sarcoma-Associated Herpesvirus Lytic Replication Is Independent of Anaphase-Promoting Complex Activity . Journal of Virology. 94. (13). American Society for Microbiology

Aaro Kasurinen and Silvia Gramolelli and Jaana Hagström and Alli Laitinen and Arto Kokkola and Yuichiro Miki and Kaisa Lehti and Masakazu Yashiro and Päivi M. Ojala and Camilla Böckelman and Caj Haglund(2019). High tissue MMP14 expression predicts worse survival in gastric cancer, particularly with a low PROX1 . Cancer Medicine. 8. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6995--7005. Wiley

Burcin Gungor and Lauri Vanharanta and Maarit Hölttä-Vuori and Juho Pirhonen and Nikolaj H.T. Petersen and Silvia Gramolelli and Päivi M. Ojala and Thomas Kirkegaard and Elina Ikonen(2019). HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo . Molecular Metabolism. 28. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 135--143. Elsevier {BV}

Jordi Gonzalez-Molina and Silvia Gramolelli and Zehuan Liao and Joseph W. Carlson and Päivi M. Ojala and Kaisa Lehti(2019). MMP14 in Sarcoma: A Regulator of Tumor Microenvironment Communication in Connective Tissues . Cells. 8. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 991. {MDPI} {AG}

Silvia Gramolelli and Jianpin Cheng and Ines Martinez-Corral and Markus Vähä-Koskela and Endrit Elbasani and Elisa Kaivanto and Ville Rantanen and Krista Tuohinto and Sampsa Hautaniemi and Mark Bower and Caj Haglund and Kari Alitalo and Taija Mäkinen and Tatiana V. Petrova and Kaisa Lehti and Päivi M. Ojala(2018). PROX1 is a transcriptional regulator of MMP14 . Scientific Reports. 8. (1). Springer Science and Business Media {LLC}

Bizunesh Abere and Naira Samarina and Silvia Gramolelli and Jessica Rückert and Gisa Gerold and Andreas Pich and Thomas F. Schulz(2018). Kaposi's Sarcoma-Associated Herpesvirus Nonstructural Membrane Protein pK15 Recruits the Class II Phosphatidylinositol 3-Kinase PI3K-C2α To Activate Productive Viral Replication . Journal of Virology. 92. (17). American Society for Microbiology

(2018). Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation . eLife.

Silvia Gramolelli and Päivi M Ojala(2017). Kaposi's sarcoma herpesvirus-induced endothelial cell reprogramming supports viral persistence and contributes to Kaposi's sarcoma tumorigenesis . Current Opinion in Virology. 26. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 156--162. Elsevier {BV}

Silvia Gramolelli and Magdalena Weidner-Glunde and Bizunesh Abere and Abel Viejo-Borbolla and Kiran Bala and Jessica Rückert and Elisabeth Kremmer and Thomas F. Schulz(2015). Inhibiting the Recruitment of PLCγ1 to Kaposi’s Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells . PLOS Pathogens. 11. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e1005105. Public Library of Science ({PLoS})

(2015). The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma . The Journal of pathology.

(2014). Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65 . Journal of virology.

(2014). Absence of the human CYP2C8*3 allele in Ugandan children exposed to Plasmodium falciparum malaria . Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

(2013). The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells . PLoS pathogens.

(2012). Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression . PLoS pathogens.

(2012). Distribution of human CYP2C8*2 allele in three different African populations . Malaria journal.

(2010). Evaluation of bloodsucking arthropod bite as possible risk co-factor in Human herpesvirus-8 transmission route. Parassitologia.