プロフィール詳細

プロジェクトを作成

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Dr. Sovannarith K.に依頼

United States

PhD Scientist & Harvard/MGH Fellow | Longevity, Oncology & STEM Communication Specialist

プロフィール概要

I am a PhD scientist and Postdoctoral Research Fellow at Massachusetts General Hospital and Harvard Medical School, specializing in the molecular mechanisms of healthy aging and cancer biology. My research focuses on how cellular alterations—specifically histone dynamics, autophagy, and mitochondrial metabolism—influence healthspan and lifespan. With a proven track record in both high-level bench science and complex project leadership, I offer consulting services in: Experimental Design & Data Analysis: Expert in human cell models (IMR90, Caco-2) and diverse animal systems (rotifers, zebrafish, mice). Scientific Writing & Editing: Extensive experience drafting NIH grant proposals (including K01), peer-reviewed manuscripts, and technical reports. STEM Education & Communication: Author and lead for bilingual (Khmer-English) educational series, specializing in translating complex biological concepts for diverse audiences. Target Identification: Deep expertise in cellular senescence and aging-related biomarkers. I am dedicated to technical accuracy, inquiry-based problem solving, and helping clients bridge the gap between fundamental research and actionable scientific insights.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Chromatin
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Histology
• ☆ Cell Culture
• ☆ Blotting
• ☆ Cell Aging

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, General Proofreading & Editing

Research User Research, Feasibility Study, Fact Checking, Scientific and Technical Research

Consulting Scientific and Technical Consulting

Data & AI Data Insights

職務経験

Postdoctoral Research Fellow

Massachusetts General Hospital

2月 2024 - 現在

Postdoctoral Research Fellow

Harvard University

2月 2024 - 現在

Postdoctoral scientist

Marine Biological Laboratory

3月 2021 - 2月 2024

Postdoctoral associate

Boston University School of Medicine

3月 2019 - 2月 2021

学歴

Ph.D. (Graduate School of Analytical Science and Technology (GRAST))

Chungnam National University

3月 2015 - 2月 2019

Master (Life Science)

Sogang University

3月 2013 - 2月 2015

Young Scientist researcher (Department of Biotechnology)

Mahidol University Faculty of Science

7月 2012 - 8月 2012

Bachelor (Biology)

Royal University of Phnom Penh

9月 2008 - 6月 2012

認定資格

• The MBL Biology of Aging Advanced Research Training Summer Course

  Marine Biological Laboratory

  7月 2023 - 現在

• The 29th NIA Training Course in Experimental Aging Research

  Buck Institute

  10月 2022 - 現在

出版物

JOURNAL ARTICLE

Kim J, Buffenstein R, Bronikowski AM, Pilar Vanegas ND, Rosas L, Agudelo-Garcia P, Mora AL, Rojas M, Englund DA, LeBrasseur NK, et al. (2024). The Fourth Annual Symposium of the Midwest Aging Consortium . The journals of gerontology. Series A, Biological sciences and medical sciences.

Sovannarith Korm, Alyssa Liguori, Alex Profetto, Emily Richters, Kristin E. Gribble (2024). Maternal age effects on offspring lifespan and reproduction vary within a species . Ecology and Evolution.

Sovannarith Korm, Yanwu Wang, Ning Shen, Gervase Spurlin, Sarah Huang, Nicole M. Anderson, Leah N. Huiting, Hudan Liu, Hui Feng(2022). α-Ketoglutarate-Mediated DNA Demethylation Sustains T-Acute Lymphoblastic Leukemia upon TCA Cycle Targeting . Cancers. 14. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2983. {MDPI} {AG}

Sovannarith Korm, Yanwu Wang, Ning Shen, Gervase Spurlin, Sarah Huang, Nicole M. Anderson, Leah N. Huiting, Hudan Liu, Hui Feng (2022). α-Ketoglutarate-Mediated DNA Demethylation Sustains T-Acute Lymphoblastic Leukemia upon TCA Cycle Targeting . Cancers.

Sovannarith Korm, Joseph E. Friedlander, Ning Shen, Aozhuo Zeng, Hui Feng(2021). Failure to Guard: Mitochondrial Protein Quality Control in Cancer . International Journal of Molecular Sciences. 22. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 8306. {MDPI} {AG}

Sovannarith Korm, Joseph E. Friedlander, Ning Shen, Aozhuo Zeng, Hui Feng (2021). Failure to Guard: Mitochondrial Protein Quality Control in Cancer . International Journal of Molecular Sciences.

(2020). The multifaceted role of protein kinase CK2 in high-risk acute lymphoblastic leukemia . Haematologica.

Sovannarith Korm, Seung Hun Han, Ye Gi Han, Soo-Young Choi, Soo-Hyun Kim, Hee Jin Chung, Kibeom Park, Jae-Young Kim, Kyungjae Myung, Joo-Yong Lee, et al.(2019). GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia . Autophagy. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--15. Informa {UK} Limited

Han SH, Korm S, Han YG, Choi SY, Kim SH, Chung HJ, Park K, Kim JY, Myung K, Lee JY, Kim H, Kim DW. GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia. Autophagy. 2019 12; 15(12):2076-2090 .

Sovannarith Korm, Suna Jung, Miae Han, Se-in Lee, Solhee Noh, Sophors Phorl, Rema Naskar, Kye-Sung Lee, Geon-Hee Kim, Yun-Jaie Choi, et al.(2018). HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression . Biochemical and Biophysical Research Communications. 503. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 285--290. Elsevier {BV}

Sovannarith Korm, Suna Jung, Miae Han, Se-in Lee, Solhee Noh, Sophors Phorl, Rema Naskar, Kye-Sung Lee, Geon-Hee Kim, Yun-Jaie Choi, et al.(2018). HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression . Biochemical and Biophysical Research Communications.

Jung, S., Han, M., Korm, S., Lee, S.-I., Noh, S., Phorl, S., Naskar, R., Lee, K.-S., Kim, G.-H., Choi, Y.-J., et al.(2018). HDAC6 regulates thermogenesis of brown adipocytes through activating PKA to induce UCP1 expression . Biochemical and Biophysical Research Communications. 503. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 285-290.

Park SY, Phorl S, Jung S, Sovannarith K, Lee SI, Noh S, Han M, Naskar R, Kim JY, Choi YJ, Lee JY. HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation. Biochem Biophys Res Commun. 2017 12 09; 494(1-2):51-56 .

Seth A, Lee H, Cho MY, Park C, Korm S, Lee JY, Choi I, Lim YT, Hong KS. Combining vasculature disrupting agent and Toll-like receptor 7/8 agonist for cancer therapy. Oncotarget. 2017 Jan 17; 8(3):5371-5381 .

Korm Sovannarith, Song-Yi Park, Sophors Phorl, Suna Jung, Se-in Lee, Solhee Noh, Miae Han, Rema Naskar, Jae-Young Kim, Yun-Jaie Choi, et al.(2017). HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation . Biochemical and Biophysical Research Communications. 494. (1-2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 51--56. Elsevier {BV}

Korm Sovannarith, Song-Yi Park, Sophors Phorl, Suna Jung, Se-in Lee, Solhee Noh, Miae Han, Rema Naskar, Jae-Young Kim, Yun-Jaie Choi, et al.(2017). HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation . Biochemical and Biophysical Research Communications. 494. (1-2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 51--56.

Korm, Sovannarith, Chung, Hee Jin, Lee, Se-In, Phorl, Sophors, Noh, Solhee, Han, Miae, Naskar, Rema, Kim, Hongtae, Lee, Joo-Yong(2017). RAP80 binds p32 to preserve the functional integrity of mitochondria . Biochemical and Biophysical Research Communications. 492. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 441-446.

Chung, H.J., Korm, S., Lee, S.-I., Phorl, S., Noh, S., Han, M., Naskar, R., Kim, H., Lee, J.-Y.(2017). RAP80 binds p32 to preserve the functional integrity of mitochondria . Biochemical and Biophysical Research Communications. 492. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 441-446.

Korm, Sovannarith, Seth, Anushree, Lee, Hyunseung, Cho, Mi Young, Park, Cheongsoo, Lee, Joo-Yong, Choi, Inpyo, Lim, Yong Taik, Hong, Kwan Soo(2017). Combining vasculature disrupting agent and toll-like receptor 7/8 agonist for cancer therapy . Oncotarget. 8. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5371-5381.

Seth, A., Lee, H., Cho, M.Y., Park, C., Korm, S., Lee, J.-Y., Choi, I., Lim, Y.T., Hong, K.S.(2017). Combining vasculature disrupting agent and toll-like receptor 7/8 agonist for cancer therapy . Oncotarget. 8. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5371-5381.

Park SY, Korm S, Chung HJ, Choi SJ, Jang JJ, Cho S, Lim YT, Kim H, Lee JY. RAP80 regulates epithelial-mesenchymal transition related with metastasis and malignancy of cancer. Cancer Sci. 2016 Mar; 107(3):267-73 .

Korm, Sovannarith, Park, Song Yi, Chung, Hee Jin, Choi, Su Jin, Jang, Jin-Ju, Cho, Sunhee, Lim, Yong Taik, Kim, Hongtae, Lee, Joo-Yong(2016). RAP80 regulates epithelial-mesenchymal transition related with metastasis and malignancy of cancer . Cancer Science. 107. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 267-273.

Park, S.Y., Korm, S., Chung, H.J., Choi, S.jin., Jang, J.-J., Cho, S., Lim, Y.T., Kim, H., Lee, J.-Y.(2016). RAP80 regulates epithelial-mesenchymal transition related with metastasis and malignancy of cancer . Cancer Science. 107. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 267-273.

Korm, Sovannarith, Jeong, Ho-Chang, Kwon, Ok-Seon, Park, Jeong-Rak, Cho, Hyeseong, Kim, Young-Mi, Chin, Young-Won, Cha, Hyuk-Jin(2015). alpha-Mangostin induces G1 cell cycle arrest in HCT116 cells through p38MAPK-p16INK4a pathway . Rsc Advances. 5. (44). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 34752-34760.

Korm, S., Jeong, H.-C., Kwon, O.-S., Park, J.-R., Cho, H., Kim, Y.-M., Chin, Y.-W., Cha, H.-J.(2015). α-Mangostin induces G1 cell cycle arrest in HCT116 cells through p38MAPK-p16INK4a pathway . RSC Advances. 5. (44). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 34752-34760.

Korm, Sovannarith, Kim, Jin-Ju, Kim, Won-Seok, Kim, Ok-Seon, Lee, Ji-Seon, Min, Hyung-Geun, Chin, Young-Won, Cha, Hyuk-Jin(2014). Nobiletin Suppresses MMP-9 Expression through Modulation of p38 MAPK Activity in Human Dermal Fibrobalsts . Biological & Pharmaceutical Bulletin. 37. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 158-163.

Kim, J.-J., Korm, S., Kim, W.-S., Kim, O.-S., Lee, J.-S., Min, H.-G., Chin, Y.-W., Cha, H.-J.(2014). Nobiletin suppresses mmp-9 expression through modulation of p38 mapk activity in human dermal fibrobalsts . Biological and Pharmaceutical Bulletin. 37. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 158-163.

PREPRINT

Sovannarith Korm, Alyssa Liguori, Alex Profetto, Emily Richters, Kristin E. Gribble (2023). Maternal age effects on offspring lifespan and reproduction vary within a species .