プロフィール詳細

プロジェクトを作成

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Srinivas N.に依頼

United States

Bioinformatician | Computational Biologist | Data Analyst | R programmer | Statistician | Scientific writer

プロフィール概要

• Development and implementation of novel pipelines and software for better understanding of genomic/transcriptomic data generated by next-generation sequencing (NGS) techniques. • Statistical programming using R. R shiny web applications for pipeline automation to streamline analyses for biologists as well as Website development using R shiny dashboard. • Analyze and interpret gene expression data by performing differential expression analysis. Data maintenance, clean-up and organization using SQL. • Experience in handling DNA/RNA sequencing data, reporting copy-number alterations, identifying somatic mutations and document them to make meaningful and understandable figures and tables for scientific publications. • Implementing Machine-Learning prediction algorithms using logistic regression models, Random Forest Classifiers, Support Vector Machines and XGBoost. • Expertise in Cancer biology, Immunology, Molecular biology and Genetics. • Manuscript preparation, analysis/figures/methodology documentation for high quality journals including poster presentation for scientific conferences.

専門分野

• ★ Bioinformatics
• ★ Phylogenetics

サービス

• Writing
• Data & AI

Writing Technical Writing

Data & AI Statistical Analysis, Algorithm Design-Non ML, Data Visualization

職務経験

Bioinformatician/Computational Biologist

University of Michigan, Ann Arbor

12月 2017 - 現在

BIoinformatician

Indiana University School of Medicine

5月 2015 - 11月 2017

学歴

Master of Science in Bioinformatics

Indiana University - Purdue University Indianapolis

1月 2015 - 12月 2016

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Zaslavsky AB, Adams MP, Cao X, Maj T, Choi JE, Stangl-Kremser J, Patel S, Putelo A, Lee SK, Nallandhighal S, et al.(2020). Platelet PD-L1 suppresses anti-cancer immune cell activity in PD-L1 negative tumors . Scientific reports.

Salami SS, Tosoian JJ, Nallandhighal S, Jones TA, Brockman S, Elkhoury FF, Bazzi S, Plouffe KR, Siddiqui J, Liu CJ, et al.(2020). Serial Molecular Profiling of Low-grade Prostate Cancer to Assess Tumor Upgrading: A Longitudinal Cohort Study . European urology.

Nallandhighal S, Tran TM(2019). Reply to Liu et al . The Journal of infectious diseases.

Salami SS, Kaplan JB, Nallandhighal S, Takhar M, Tosoian JJ, Lee M, Yoon J, Hovelson DH, Plouffe KR, Kaffenberger SD, et al.(2019). Biologic Significance of Magnetic Resonance Imaging Invisibility in Localized Prostate Cancer . JCO precision oncology.

Nallandhighal S, Park GS, Ho YY, Opoka RO, John CC, Tran TM(2019). Whole-Blood Transcriptional Signatures Composed of Erythropoietic and NRF2-Regulated Genes Differ Between Cerebral Malaria and Severe Malarial Anemia . The Journal of infectious diseases.

Nallandhighal S, Park G, Ho Y, Opoka R, John C, Tran T(2018). 963. Whole Blood Transcriptome Analysis Reveals Differences in Erythropoiesis and Neurologically Relevant Pathways Between Cerebral Malaria and Severe Malarial Anemia . Open forum infectious diseases.

Clemente TM, Mulye M, Justis AV, Nallandhighal S, Tran TM, Gilk SD(2018). Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages . Infection and immunity.

PREPRINT

Clemente TM, Mulye M, Justis AV, Nallandhighal S, Tran TM, Gilk SD(2018). Coxiella burnetiiblocks intracellular IL-17 signaling in macrophages .