プロフィール詳細

プロジェクトを作成

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Dr. Subbaiah C.に依頼

United States

Plant biologist with interdisciplinary expertise and 20+ years experience in industry and academia

プロフィール概要

-Assistant Professor (Research), LSU AgCenter Maize seed development and pathology focused on aflatoxin mitigation -Senior Postdoctoral Fellow, LSU Genomics and transcriptomics of salt tolerance, insect-virus interactions -Senior Scientist, Valent BioSciences • Developed high throughput screens to identify chemicals that confer drought/heat tolerance using crop model systems. A flooding assay was in works. • Developed a novel plant culture method needed for high throughput stress tolerance screens • Tested the translatability of putative hits in higher tier screens in maize and canola in growth rooms and the greenhouse. A soybean greenhouse screen was in development. • In collaboration with field scientists, identified a plant growth regulator for maize yield enhancement in drought • Worked on the mode of action of a proprietary growth promoter and in the process, discovered novel commercial utility • Identified and evaluated novel groups of compounds affecting root architecture and drought/flooding stress tolerance … -post-doc, Colorado State University -Developed an semi-in vivo system to study pollen-pistil interactions and reproductive behavior -Studied temporal and developmental dynamics of reproductive barriers and associated proteins -Characterized the mode of action of a peptide growth hormone and its interactions with its putative receptor and a cysteine protease in tomato pollen tubes -Assembled a multi-functional insertion mutagenesis tool for tomato and generated mutant lines … Arizona State University • Identified potential multi-tasking abilities of sucrose synthase and mitochondrial porin (VDAC), their interactions and putative mitochondrial and nuclear functions during flooding stress • Demonstrated the involvement of mitochondrial reactive oxygen species (mtROS) in the retrograde regulation of anaerobic genes; Carried out microarray analyses Principal Investigator, Monsanto Coordinated a part of soybean functional genomics pipeline focused on greenhouse and field screening for yield enhancement as well as drought tolerance • Worked in close collaboration with the maize yield group • Identified novel pathway-based strategies • Carried out molecular & phenotypic validation of RNAi-transgenics • Unraveled flowering time control pathway in soybean using transcription factor and physiological analysis, transgenic and gene expression analyses • Advanced lead genes to mode of action analysis by transcriptome-profiling • Optimization of transgene expression and promoter discovery • Authored ~10 disclosures and updates, 3 best practice documents; Organized and chaired Monsanto Technical Symposia Senior Scientist, DNA Plant Tech • Worked on transgenic improvement fungal tolerance by expression of multiple genes; Developed a new and >10x faster RNA isolation protocol for strawberry • Prepared a disclosure on “Novel approaches for gene stacking in plant binary vectors” University of Illinois at Urbana-Champaign Senior Research Specialist, Principal Research Specialist Company NameUniversity of Illinois at Urbana-Champaign Dates EmployedJul 1992 – Dec 2000 Employment Duration8 yrs 6 mos • Discovered the Ca2+-mediated oxygen signaling pathway in maize (a pathway conserved across plant species) using a chemical screening approach, –a paradigm shift in plant Ca2+ signaling. • Demonstrated that selective cell death can be a potent stress tolerance mechanism under flooding stress; Identified the involvement of a Ca2+-dependent cysteine-protease in the anoxic cell death • Identified isoform-specific regulation of sucrose synthase (SUS) phosphorylation in maize roots subjected to flooding and associated effects on callose biosynthesis. Generated putative sh1-suppressor mutant lines to reveal potential new regulators of SUS during kernel development • Cloned a novel calmodulin-binding Ca2+-pump (CAP1) and functionally characterized by complementation in yeast mutants lacking in Ca2+-ATPases; Identified the CaM-binding domain • Initiated studies on the role of Ca2+-homeostasis in global gene expression, using a yeast mutant lacking Ca2+ pumps; Preliminarily identified potential regulons involved in membrane & cell wall biogenesis and transcriptional adaptation to anoxia … see more University of Missouri-Columbia Post-doc Company NameUniversity of Missouri-Columbia Dates EmployedFeb 1992 – Jul 1992 Employment Duration6 mos -Initiated a new project on oxygen signaling in plants using maize flooding stress as a model system -Developed phenotypic, biochemical and molecular screens for identifying small molecules that interfere with hypoxia signaling -Assembled and screened a small library of compounds and identified ruthenium red as a potent inhibitor of the pathway -Acted as the lab manager when my PI and our lab transitioned to University of Illinois … see more ICGEB Scientist Company NameICGEB Dates Employed1988 – 1992 Employment Duration4 yrs • Purified and biochemically characterized chloroplast RNA-binding proteins; Identified the RNA-binding domain; Characterized protein-RNA/DNA interactions Madurai Kamaraj University Graduate Student Company NameMadurai Kamaraj University Dates Employed1983 – 1988 Employment Duration5 yrs Show 2 more experiences

専門分野

• ★ Agriculture
• ☆ Agricultural Chemistry
• ☆ Plant Pathology
• ☆ Plant Breeding & Genetics
• ☆ Plant Physiology
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Biotechnology & Bioengineering
• ☆ Agroecology

サービス

• Writing
• Research
• Data & AI
• Product Development

Writing Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Data Visualization

Product Development Formulation

職務経験

Asssitant Professor (Research)

LSU Agricultural Center

2014 - 現在

Senior Scientist

Valent Bioscinces

1月 2010 - 10月 2012

学歴

PhD (Plant Sciences)

Madurai Kamaraj University

1984 - 1989

認定資格

• 認定資格の詳細は未入力です。

出版物

OTHER

Subbaiah Chalivendra, Fangneng Huang, Mark Busman, W. Paul Williams, Jong Hyun Ham, Geromy G. Moore(2020). Low aflatoxin levels and flowering delay in Aspergillus flavus-resistant maize lines are correlated with increased corn earworm damage and enhanced seed fumonisin content . Cold Spring Harbor Laboratory

JOURNAL ARTICLE

Subbaiah Chalivendra, Catherine DeRobertis, Jorge Reyes Pineda, Jong Ham, Kenneth Damann(2018). Rice Phyllosphere Bacillus Species and Their Secreted Metabolites Suppress Aspergillus flavus Growth and Aflatoxin Production In Vitro and In Maize Seeds . Toxins. 10. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 159. {MDPI} {AG}

(2018). Rice Phyllosphere Bacillus Species and Their Secreted Metabolites Suppress <i>Aspergillus flavus</i> Growth and Aflatoxin Production In Vitro and In Maize Seeds . Toxins.

Chalivendra, S.C., De Robertis, C., Chang, P.-K., Damann, K.E.(2017). Cyclopiazonic acid is a pathogenicity factor for aspergillus flavus and a promising target for screening germplasm for ear rot resistance . Molecular Plant-Microbe Interactions. 30. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 361-373.

Chalivendra, S.C., Lopez-Casado, G., Kumar, A., Kassenbrock, A.R., Royer, S., Tovar-M&#232;ndez, A., Covey, P.A., Dempsey, L.A., Randle, A.M., Stack, S.M., et al.(2013). Developmental onset of reproductive barriers and associated proteome changes in stigma/styles of Solanum pennellii . Journal of Experimental Botany. 64. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 265-279.

Ren, M., Venglat, P., Ren, M., Venglat, P., Qiu, S., Feng, L., Cao, Y., Wang, E., Xiang, D., Wang, J., et al.(2013). Target of rapamycin signaling regulates metabolism, growth, and life Span in arabidopsis . Plant Cell. 24. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4850-4874.

Rhoads, D & Subbaiah, C, 2007, 'Mitochondrial retrograde regulation in plants', <i>Mitochondrion</i>, vol. 53, no. 3, pp. 247-194 .

Sachs, M, Subbaiah, C & Saab, I, 1996, 'Anaerobic gene expression and flooding tolerance in maize', <i>Journal of Experimental Botany</i>, vol. 47, no. 1, pp. 1-15 .