プロフィール詳細

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Dr. Sufi R.に依頼

India

~10 years of post-PhD experience in mitochondria, cell biology, imaging, fluorescent probes and Nano-biotechnology.

プロフィール概要

I am Dr. Sufi Raja, a trained Biochemist, Cell Biologist and Nano-biotechnologist with extensive experience in fluorescent probes/biosensor development and biological imaging. I have completed my PhD in Biochemistry in 2015 from University of Calcutta, India. During my PhD I worked on synthesis and surface modification of metallic nanoparticles and its interaction with proteins and cells. Then I moved to inStem, India for my first postdoctoral training from 2015-2018. At inStem I developed probes for imaging of mitochondria function in living cells and tissues. After that I moved to Duke University, USA for my second postdoctoral training from 2018-2021. At Duke University I used quantitative imaging to study dynamics of microtubule and mitochondria. I also used state-of-the-art super resolution microscopy to monitor activity dependent change in distance between two membranes mitochondria. After coming back from USA I was briefly associated with University of Hyderabad, India as an imaging scientist. Finally, I joined SASTRA University, India as an assistant professor (research) at the department of Biotechnology. Currently, I am working as freelancer to provide assistance in writing research grants and consultation for troubleshooting microscopy and imaging related problems. The main focus of my research is to develop and apply diverse tool-chest of functional fluorescent probes to monitor the activity of cellular power plant, mitochondria, in real time and use the information to understand the homeostasis of this highly dynamic organelle in a comprehensive manner in the context of cell activation, migration and differentiation. Migration is the key process in development, wound healing and cancer metastasis. Migration like mechanical functions are achieved via regulated cytoskeletal network remodelling. Interestingly, all these processes need energy. It will be interesting to explore if cells actively maintain any energy management system to execute function in spatiotemporally controlled manner. Specifically, how cells manage mitochondrial dynamics to execute energy consuming cellular processes precisely and robustly. Addressing such fundamental question not only will enrich our understanding regarding coupling between cellular energetics and dynamics it will also be useful to design mitochondria-targeted therapeutic approaches to deal with mitochondrial dysfunction related disorders.

専門分野

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Culture
• ☆ Peer Review
• ☆ Research Methodology

サービス

• Writing
• Research
• Consulting

Writing General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

職務経験

Freelancer

Freelancer

7月 2024 - 現在

Assistant professor (Research)

Shanmugha Arts Science Technology and Research Academy School of Chemical and Biotechnology

1月 2023 - 現在

Assistant Professor / Associate Professor

SASTRA University

1月 2023 - 5月 2024

Imaging Scientist

University of Hyderabad

9月 2021 - 10月 2022

Postdoctoral Associate

Duke University

7月 2019 - 6月 2021

Postdoctoral Researcher

Georg-August-Universität Göttingen

11月 2018 - 5月 2019

SERB- National Postdoctoral Fellow

InStem (Institute for Stem Cell and Regenerative Medicine)

1月 2017 - 10月 2018

Postdoctoral Fellow

Institute for Stem Cell Science and Regenerative Medicine

9月 2015 - 10月 2018

学歴

Doctor of Philosophy

University of Calcutta

9月 2008 - 2月 2015

PhD (Biochemistry)

University of Calcutta

2008 - 2015

Master of Science (Biochemistry)

University of Calcutta

2005 - 2007

Bachelor of Science (Chemistry)

Presidency College, University of Calcutta

2001 - 2004

認定資格

• 認定資格の詳細は未入力です。

出版物

PREPRINT

Fouzia Kalim, Sivaraman Gandhi, Arati Ramesh, Sufi O. Raja, Akash Gulyani (2023). A red-shifted donor-acceptor hemicyanine-based probe for mitochondrial pH in live cells .

Sufi O. Raja and Sanjay Chatterjee and Anjan Kr. Dasgupta(2017). Antiferromagnetic switch in serum . []. Cold Spring Harbor Laboratory

(2014). Instant Response of Live HeLa Cells to Static Magnetic Field and Its Magnetic Adaptation.

JOURNAL ARTICLE

Gaurav Singh, Geen George, Sufi O. Raja, Ponnuvel Kandaswamy, Manoj Kumar, Shashi Thutupalli, Sunil Laxman, Akash Gulyani (2023). A molecular rotor FLIM probe reveals dynamic coupling between mitochondrial inner membrane fluidity and cellular respiration . Proceedings of the National Academy of Sciences.

Sufi O. Raja and Alexey I. Chizhik and Christoph F. Schmidt and Jörg Enderlein and Arindam Ghosh(2021). Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging . Nano Letters. American Chemical Society ({ACS})

Sufi O. Raja and Gandhi Sivaraman and Sayan Biswas and Gaurav Singh and Fouzia Kalim and Ponnuvel Kandaswamy and Akash Gulyani(2021). A Tunable Palette of Molecular Rotors Allows Multicolor, Ratiometric Fluorescence Imaging and Direct Mapping of Mitochondrial Heterogeneity . ACS Applied Bio Materials. 4. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4361--4372. American Chemical Society ({ACS})

Anirban Bose and Rajdeep Chowdhury and Somen Nandi and Sufi O. Raja and Sanhita Ray and Kankan Bhattacharyya and Anjan Kr Dasgupta(2020). Time-dependent enhancement of fluorescence from Rhodobacter capsulatus SB1003 and its critical dependence on concentration temperature and static magnetic field . Journal of Biological Physics. 46. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 151--167. Springer Science and Business Media {LLC}

P. Chinna Ayya Swamy and Gandhi Sivaraman and Ragam N. Priyanka and Sufi O. Raja and Kandhasamy Ponnuvel and Jeyabalan Shanmugpriya and Akash Gulyani(2020). Near Infrared (NIR) absorbing dyes as promising photosensitizer for photo dynamic therapy . Coordination Chemistry Reviews. 411. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 213233. Elsevier {BV}

Radhika Arasala Rao and Alhad Ashok Ketkar and Neelam Kedia and Vignesh K Krishnamoorthy and Vairavan Lakshmanan and Pankaj Kumar and Abhishek Mohanty and Shilpa Dilip Kumar and Sufi O Raja and Akash Gulyani and Chandra Prakash Chaturvedi and Marjorie Brand and Dasaradhi Palakodeti and Shravanti Rampalli(2019). KMT 1 family methyltransferases regulate heterochromatin–nuclear periphery tethering via histone and non‐histone protein methylation . EMBO reports. 20. (5). {EMBO}

Sufi O. Raja and Gandhi Sivaraman and Ananya Mukherjee and Chellappa Duraisamy and Akash Gulyani(2017). Facile Synthesis of Highly Sensitive, Red-Emitting, Fluorogenic Dye for Microviscosity and Mitochondrial Imaging in Embryonic Stem Cells . ChemistrySelect. 2. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4609--4616. Wiley

Sufi Raja and Anjan Dasgupta(2016). Magnetism of tryptophan and walk memory of proteins . Matters Archive. Sciencematters

Tamoghna Bhattacharyya and Arumoy Chatterjee and Budhaditya Chatterjee and Sufi O. Raja and Anjan Kr. Dasgupta(2015). Real-time electro-diffusion method to discriminate carbon nanomaterials . ELECTROPHORESIS. 36. (24). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3009--3013. Wiley

M. Azharuddin and J. Khandelwal and H. Datta and A. K. Dasgupta and S. O. Raja(2015). Dry Eye: A Protein Conformational Disease . Investigative Ophthalmology & Visual Science. 56. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1423--1429. Association for Research in Vision and Ophthalmology ({ARVO})

Jyoti Shaw and Sufi O Raja and Anjan Kr Dasgupta(2014). Modulation of cytotoxic and genotoxic effects of nanoparticles in cancer cells by external magnetic field . Cancer Nanotechnology. 5. (1). Springer Science and Business Media {LLC}

Sufi O. Raja and Jyoti Shaw and Arnab Chattopadhyay and Sanjoy Chatterjee and Maitreyee Bhattacharya and Anjan K. Dasgupta(2014). Synchronous fluorescence based one step optical method for assessing oxidative stress and its dependence on serum ferritin . Analytical Methods. 6. (16). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6228. Royal Society of Chemistry ({RSC})

Mallar Ray and Tuhin Shuvra Basu and Nil Ratan Bandyopadhyay and Robert F. Klie and Siddhartha Ghosh and Sufi Oasim Raja and Anjan K. Dasgupta(2014). Highly lattice-mismatched semiconductor–metal hybrid nanostructures: gold nanoparticle encapsulated luminescent silicon quantum dots . Nanoscale. 6. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2201. Royal Society of Chemistry ({RSC})

Abhishek Bhattacharya and Madhurima Chakraborty and Sufi O. Raja and Avijit Ghosh and Maitrayee Dasgupta and Anjan Kr. Dasgupta(2014). Static magnetic field (SMF) sensing of the P723/P689photosynthetic complex . Photochem. Photobiol. Sci. 13. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1719--1729. Springer Science and Business Media {LLC}

Sufi O. Raja and Anjan K. Dasgupta(2012). Magnetic field induced self assembly and optical memory of pi-ring containing fluorophores . Chemical Physics Letters. 554. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 163--167. Elsevier {BV}

Suryyani Deb and S.O. Raja and Anjan Kr. Dasgupta and Rajkumar Sarkar and Asoke P. Chattopadhyay and Utpal Chaudhuri and Pradipta Guha and Partha Sardar(2012). Surface tunability of nanoparticles in modulating platelet functions . Blood Cells, Molecules, and Diseases. 48. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 36--44. Elsevier {BV}

Sarmishtha Ghoshal and Abul AM Ansar and Sufi O Raja and Arpita Jana and Nil R Bandyopadhyay and Anjan K Dasgupta and Mallar Ray(2011). Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications . Nanoscale Research Letters. 6. (1). Springer Science and Business Media {LLC}

S. Banerjee and S. O. Raja and M. Sardar and N. Gayathri and B. Ghosh and A. Dasgupta(2011). Iron oxide nanoparticles coated with gold: Enhanced magnetic moment due to interfacial effects . Journal of Applied Physics. 109. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 123902. {AIP} Publishing