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プロフィール詳細
プロジェクトを作成
★★★★★
☆☆☆☆☆
Dr. Thokhir Basha S.に依頼
India

11+ Years in Biotech, Statistics, Bioinformatics & Data Analytics | Skilled in Python, R, SQL, ADMET NGS Docking PowerBI

プロフィール概要
専門分野
サービス
Writing Non-Medical Regulatory Writing, Technical Writing, Creative Writing, Newswriting, General Proofreading & Editing
Research Market Research, User Research, Gray Literature Search, Scientific and Technical Research, Secondary Data Collection
Consulting Go-to-Market Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting
Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-ML, Data Visualization, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing
Product Development Formulation, Recipe Development, Stability/Shelf Life Testing, Product Validation, Concept Development, Packaging Design
職務経験

Researcher, Research Associate

SRKR Engineering College

11月 2020 - 現在

Junior Research Scientist

Eesavyasa Technologies Pvt.Ltd

11月 2017 - 4月 2019

Project Assistant II

Indian Institute of Chemical Technology

12月 2006 - 3月 2012

学歴

Ph.D (Medicinal chemistry and pharmacology & IPS (Institute of pharmaceutical sciences))

Indian Institute of Chemical Technology and King's college London

9月 2012 - 7月 2019

Ph. D

Indian Institute of Chemical Technology

9月 2012 - 10月 2016

M.Sc (Master of Science)

Bharathidasan University

3月 2004 - 4月 2006

認定資格
  • Data Science for Biologists Hands-on Internship

    BioTecNika

    3月 2025 - 現在

  • Drug Discovery & Development

    Decode LIFE (UDYAM-HR-xxxxxxx)

    11月 2023 - 現在

  • Life Member of Scholars Academic & Scientific Society

    Scholars Academic & Scientific Society
    http://www.sassociety.com

    7月 2023 - 現在

  • Python for Biologists

    The Institute of Biotechnological Research (UDYAM-GJ-xxxxxxxxxx)

    6月 2023 - 現在

  • Cancer Genomics with NGS

    Decode LIFE (UDYAM-HR-xxxxxxx)

    3月 2024 - 4月 2024

出版物
JOURNAL ARTICLE
Jalasutram, J.K., Nowduri, A., Kumari, P.P., Shaik, T.B.(2024). First-Time Investigation of Bombax ceiba Stem Crude Extract’s Role for Autoclave-assisted Silver Nanoparticle Synthesis from Silver Sulphate and Silver Nitrate: Multifaceted Characterization, Catalytic and Antibacterial Investigations . Moroccan Journal of Chemistry. 12. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 199-220.
Shaikh Faazil, M. Shaheer Malik, Saleh A. Ahmed, Qazi Mohammad Sajid Jamal, Shaikh Thoukhir Basha, Munirah M. Al-Rooqi, Rami J. Obaid, Jihan Qurban, Iqbal N Shaikh, Basim H. Asghar, et al. (2023). New quinoline-thiolactone conjugates as potential antitubercular and antibacterial agents . Journal of Molecular Structure.
M. Shaheer Malik, Syed Farooq Adil, Ziad Moussa, Hatem M. Altass, Ismail I. Althagafi, Moataz Morad, Mohammad Azam Ansari, Qazi Mohammad Sajid Jamal, Rami J. Obaid, Abdulrahman A. Al-Warthan, et al. (2021). Rational Design and Synthesis of Naphthalene Diimide Linked Bis-Naphthalimides as DNA Interactive Agents . Frontiers in Chemistry.
Malik, M.S., Farooq Adil, S., Moussa, Z., Altass, H.M., Althagafi, I.I., Morad, M., Ansari, M.A., Sajid Jamal, Q.M., Obaid, R.J., Al-Warthan, A.A., et al.(2021). Rational Design and Synthesis of Naphthalene Diimide Linked Bis-Naphthalimides as DNA Interactive Agents . Frontiers in Chemistry. 9.
Thoukhir B. Shaik, M. Shaheer Malik, Sunitha R. Routhu, Zaki S. Seddigi, Ismail I. Althagafi, Ahmed Kamal (2020). Evaluation of Anticancer and Anti-Mitotic Properties of Quinazoline and Quinazolino-Benzothiadiazine Derivatives . Anti-Cancer Agents in Medicinal Chemistry.
Thoukhir B. Shaik, M. Shaheer Malik, Sunitha R. Routhu, Zaki S. Seddigi, Ismail I. Althagafi, Ahmed Kamal(2020). Evaluation of Anticancer and Anti-Mitotic Properties of Quinazoline and Quinazolino-Benzothiadiazine Derivatives . Anti-Cancer Agents in Medicinal Chemistry. 20. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 599--611. Bentham Science Publishers Ltd.
Shaik, T.B., Malik, M.S., Routhu, S.R., Seddigi, Z.S., Althagafi, I.I., Kamal, A.(2020). Evaluation of anticancer and anti-mitotic properties of quinazoline and quinazolino-benzothiadiazine derivatives . Anti-Cancer Agents in Medicinal Chemistry. 20. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 599-611.
Mahesh R, Nayak VL, Babu KS, Riyaz S, Shaik TB, Kumar GB, Mallipeddi PL, Reddy CR, Shekar KC, Jose J, et al. (2017). Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors . ChemMedChem.
Mahesh R, Nayak VL, Babu KS, Riyaz S, Shaik TB, Kumar GB, Mallipeddi PL, Reddy CR, Shekar KC, Jose J, et al.(2017). Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors . ChemMedChem.
A.V. Subba Rao, Konderu Swapna, Siddiq Pasha Shaik, V. Lakshma Nayak, T. Srinivasa Reddy, Satish Sunkari, Thokhir Basha Shaik, Chandrakant Bagul, Ahmed Kamal (2017). Synthesis and biological evaluation of cis -restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers . Bioorganic & Medicinal Chemistry.
Subba Rao, A.V., Swapna, K., Shaik, S.P., Lakshma Nayak, V., Srinivasa Reddy, T., Sunkari, S., Shaik, T.B., Bagul, C., Kamal, A.(2017). Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers . Bioorganic and Medicinal Chemistry. 25. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 977-999.
Shaik, T.B., Hussaini, S.M.A., Nayak, V.L., Sucharitha, M.L., Malik, M.S., Kamal, A.(2017). Rational design and synthesis of 2-anilinopyridinyl-benzothiazole Schiff bases as antimitotic agents . Bioorganic and Medicinal Chemistry Letters. 27. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2549-2558.
Mahesh, R., Nayak, V.L., Babu, K.S., Riyaz, S., Shaik, T.B., Kumar, G.B., Mallipeddi, P.L., Reddy, C.R., Shekar, K.C., Jose, J., et al.(2017). Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors . ChemMedChem. 12. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 678-700.
Sultana, F., Shaik, S.P., Nayak, V.L., Hussaini, S.M.A., Marumudi, K., Sridevi, B., Shaik, T.B., Bhattacharjee, D., Alarifi, A., Kamal, A.(2017). Design, Synthesis and Biological Evaluation of 2-Anilinopyridyl-Linked Oxindole Conjugates as Potent Tubulin Polymerisation Inhibitors . ChemistrySelect. 2. (31). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9901-9910.
Subba Rao AV, Swapna K, Shaik SP, Lakshma Nayak V, Srinivasa Reddy T, Sunkari S, Shaik TB, Bagul C, Kamal A (2016). Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers . Bioorganic & medicinal chemistry.
Subba Rao AV, Swapna K, Shaik SP, Lakshma Nayak V, Srinivasa Reddy T, Sunkari S, Shaik TB, Bagul C, Kamal A(2016). Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers . Bioorganic & medicinal chemistry.
Hussaini, S.M.A., Yedla, P., Babu, K.S., Shaik, T.B., Chityal, G.K., Kamal, A.(2016). Synthesis and Biological Evaluation of 1,2,3-triazole tethered Pyrazoline and Chalcone Derivatives . Chemical Biology and Drug Design. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 97-109.
Ashraf, M., Shaik, T.B., Malik, M.S., Syed, R., Mallipeddi, P.L., Vardhan, M.V.P.S.V., Kamal, A.(2016). Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as antimitotic agents with apoptosis inducing ability . Bioorganic and Medicinal Chemistry Letters. 26. (18). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4527-4535.
Kamal A, Ashraf M, Basha ST, Ali Hussaini SM, Singh S, Vishnuvardhan MV, Kiran B, Sridhar B(2015). Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors . Organic & biomolecular chemistry.
Kamal A, Shaik TB, Malik MS(2015). Embracing synthetic lethality of novel anticancer therapies . Expert opinion on drug discovery.
Kamal, A., Shaik, T.B., Malik, M.S.(2015). Embracing synthetic lethality of novel anticancer therapies . Expert Opinion on Drug Discovery. 10. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1119-1132.
Kamal A, Hussaini SM, Nayak VL, Malik MS, Sucharitha ML, Shaik TB, Ashraf M, Bagul C(2014). Synthesis of 2-anilinopyridine dimers as microtubule targeting and apoptosis inducing agents . Bioorganic & medicinal chemistry.
Kamal A, Balakrishna M, Nayak VL, Shaik TB, Faazil S, Nimbarte VD(2014). Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents . ChemMedChem.
Kamal A, Shaik B, Nayak VL, Nagaraju B, Kapure JS, Shaheer Malik M, Shaik TB, Prasad B(2014). Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers . Bioorganic & medicinal chemistry.
Kamal, A., Balakrishna, M., Nayak, V.L., Shaik, T.B., Faazil, S., Nimbarte, V.D.(2014). Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: Microtubule-destabilizing agents . ChemMedChem. 9. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2766-2780.
Kamal, A., Ali Hussaini, S.M., Lakshma Nayak, V., Shaheer Malik, M., Lakshmi Sucharitha, M., Shaik, T.B., Ashraf, M., Bagul, C.(2014). Synthesis of 2-anilinopyridine dimers as microtubule targeting and apoptosis inducing agents . Bioorganic and Medicinal Chemistry. 22. (24). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6755-6767.
Kamal, A., Shaik, B., Nayak, V.L., Nagaraju, B., Kapure, J.S., Shaheer Malik, M., Shaik, T.B., Prasad, B.(2014). Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers . Bioorganic and Medicinal Chemistry. 22. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5155-5167.
(2012). Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors . European Journal of Medicinal Chemistry.
(2012). p53–Mdm2 inhibitors: patent review (2009 – 2010) . Expert Opinion on Therapeutic Patents.
Kamal, A., Mallareddy, A., Suresh, P., Shaik, T.B., Lakshma Nayak, V., Kishor, C., Shetti, R.V.C.R.N.C., Sankara Rao, N., Tamboli, J.R., Ramakrishna, S., et al.(2012). Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents . Bioorganic and Medicinal Chemistry. 20. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3480-3492.
Kamal, A., Mallareddy, A., Suresh, P., Lakshma Nayak, V., Shetti, R.V.C.R.N.C., Sankara Rao, N., Tamboli, J.R., Shaik, T.B., Vishnuvardhan, M.V.P.S., Ramakrishna, S.(2012). Synthesis and anticancer activity of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxins as apoptotic inducing agents . European Journal of Medicinal Chemistry. 47. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 530-545.
Kamal, A., Mohammed, A.A., Shaik, T.B.(2012). P53-Mdm2 inhibitors: Patent review (2009-2010) . Expert Opinion on Therapeutic Patents. 22. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 95-105.
Kamal, A., Srikanth, Y.V.V., Khan, M.N.A., Ashraf, Md., Shaik, T.B., Kalivendi, S.V.(2012). Synthesis, anticancer activity and inhibition of tubulin polymerization of bisindole sulfonates . Letters in Drug Design and Discovery. 9. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 242-250.
Kamal, A., Kashi Reddy, M., Shaik, T.B., Rajender, Srikanth, Y.V.V., Santhosh Reddy, V., Bharath Kumar, G., Kalivendi, S.V.(2012). Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors . European Journal of Medicinal Chemistry. 50. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 9-17.
Kamal A, Srikanth YV, Ashraf M, Khan MN, Shaik TB, Kalivendi SV, Suri N, Saxena AK(2011). Synthesis and anticancer activities of new Benzothiadiazinyl Hydrazinecarboxamides and Anilino[1,2,4]triazolo[1,5-b][1,2,4]thiadiazine 5,5-diones. Medicinal chemistry (Shariqah (United Arab Emirates)).
Raju BC, Rao RN, Suman P, Yogeeswari P, Sriram D, Shaik TB, Kalivendi SV(2011). Synthesis, structure-activity relationship of novel substituted 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer agents . Bioorganic & medicinal chemistry letters.
Kamal, A., Shiva Kumar, M., Ganesh Kumar, C., Shaik, T.B.(2011). Bioconversion of acrylonitrile to acrylic acid by Rhodococcus ruber strain AKSH-84 . Journal of Microbiology and Biotechnology. 21. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 37-42.
China Raju, B., Nageswara Rao, R., Suman, P., Yogeeswari, P., Sriram, D., Shaik, T.B., Kalivendi, S.V.(2011). Synthesis, structure-activity relationship of novel substituted 4H-chromen-1,2,3,4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer agents . Bioorganic and Medicinal Chemistry Letters. 21. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2855-2859.
Jain, N., Yada, D., Shaik, T.B., Vasantha, G., Reddy, P.S., Kalivendi, S.V., Sreedhar, B.(2011). Synthesis and antitumor evaluation of nitrovinyl biphenyls: Anticancer agents based on allocolchicines . ChemMedChem. 6. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 859-868.
Kamal, A., Suresh, P., Mallareddy, A., Kumar, B.A., Reddy, P.V., Raju, P., Tamboli, J.R., Shaik, T.B., Jain, N., Kalivendi, S.V.(2011). Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents . Bioorganic and Medicinal Chemistry. 19. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2349-2358.
Kamal, A., Bharathi, E.V., Reddy, J.S., Ramaiah, M.J., Dastagiri, D., Reddy, M.K., Viswanath, A., Reddy, T.L., Shaik, T.B., Pushpavalli, S.N.C.V.L., et al.(2011). Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents . European Journal of Medicinal Chemistry. 46. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 691-703.
Kamal, A., Srikanth, Y.V.V., Shaik, T.B., Khan, M.N.A., Ashraf, M., Reddy, M.K., Kumar, K.A., Kalivendi, S.V.(2011). 2-Anilinonicotinyl linked 1,3,4-oxadiazole derivatives: Synthesis, antitumour activity and inhibition of tubulin polymerization . MedChemComm. 2. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 819-823.
Kamal, A., Srikanth, Y.V.V., Ashraf, Md., Khan, M.N.A., Shaik, T.B., Kalivendi, S.V., Suri, N., Saxena, A.K.(2011). Synthesis and anticancer activities of new benzothiadiazinyl hydrazinecarboxamides and anilino[1,2,4]triazolo[1,5-b][1,2,4]thiadiazine 5,5-diones . Medicinal Chemistry. 7. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 165-172.
Suresh G, Reddy PP, Babu KS, Shaik TB, Kalivendi SV(2010). Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium . Bioorganic & medicinal chemistry letters.
Kamal A, Srikanth YV, Khan MN, Shaik TB, Ashraf M(2010). Synthesis of 3,3-diindolyl oxyindoles efficiently catalysed by FeCl3 and their in vitro evaluation for anticancer activity . Bioorganic & medicinal chemistry letters.
Yadav JS, Satyanarayana K, Sreedhar P, Srihari P, Shaik TB, Kalivendi SV(2010). Total synthesis of (+/-)-elegansidiol, (+/-)-farnesiferol B, and (+/-)-farnesiferol D . Bioorganic & medicinal chemistry letters.
Kamal, A., Srikanth, Y.V.V., Khan, M.N.A., Shaik, T.B., Ashraf, M.(2010). Synthesis of 3,3-diindolyl oxyindoles efficiently catalysed by FeCl <sub>3</sub> and their in vitro evaluation for anticancer activity . Bioorganic and Medicinal Chemistry Letters. 20. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5229-5231.
Yadav, J.S., Satyanarayana, K., Sreedhar, P., Srihari, P., Shaik, T.B., Kalivendi, S.V.(2010). Erratum: Total synthesis of (±)-elegansidiol, (±)- farnesiferol B and (±)-farnesiferol D (Bioorganic and Medicinal Chemistry Letters (2010) 20 (3814) DOI: 10.1016/j.bmcl.2010.04.030) . Bioorganic and Medicinal Chemistry Letters. 20. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6863.
Yadav, J.S., Satyanarayana, K., Sreedhar, P., Srihari, P., Shaik, T.B., Kalivendi, S.V.(2010). Total synthesis of (±)-elegansidiol, (±)-farnesiferol B, and (±)-farnesiferol D . Bioorganic and Medicinal Chemistry Letters. 20. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3814-3817.
Suresh, G., Prabhakar Reddy, P., Suresh Babu, K., Shaik, T.B., Kalivendi, S.V.(2010). Two new cytotoxic labdane diterpenes from the rhizomes of Hedychium coronarium . Bioorganic and Medicinal Chemistry Letters. 20. (24). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7544-7548.
Kamal, A., Rajender, Reddy, D.R., Reddy, M.K., Balakishan, G., Shaik, T.B., Chourasia, M., Sastry, G.N.(2009). Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential . Bioorganic and Medicinal Chemistry. 17. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1557-1572.
OTHER
Shaik, T.B., Shaheer Malik, M., Seddigi, Z.S., Routhu, S.R., Kamal, A.(2017). Evaluation of anticancer and anti-mitotic properties of quinazoline and quinazolino-benzothiadiazine derivatives . bioRxiv.