プロフィール詳細

プロジェクトを作成

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Tanaïs M.に依頼

France

Biosciences and bioengineering Expert - PasteurInstitute X OxfordUni X EcoleNormaleSupérieureLyon

プロフィール概要

Passionate, curious, and hard-working researcher with a keen interest in therapeutics and applied biosciences. Currently doing a PhD in phage therapy at the Pasteur Institute (Paris), with an aim to provide more efficient and safer therapeutic approaches for clinical treatments via combination therapy (ex: Phage cocktail + antimicrobial). Development and testing of in vivo murin models (project design certification). Acquired hands-on research experience in leading laboratories: - Oxford, NDORMS, Botnar Institute, Space Innovation Lab: => aging research, senescence in osteoarthritis (OA) and rheumatoid arthritis (RA) models + bioinformatics (scRNA seq, multiplex IF analysis) => 2 papers on the way - Roche, Institute of Human biology, Applied Organoid technologies team: => Projects: in vitro 3D endometriosis lesion modeling and project design, immune-competent intestinal inflammation model. => Work: Project design and dev. from ground up (funding secured). Tissue sourcing and processing, intestine-on-a-chip, cell line engineering (lenti), cytokine multiplex, transwell-based assays, RT-qPCR, IHC, live-imaging. Developed a RT-qPCR good practices guide (calc. and stats). New immunoassay device negotiation. - ETH Zürich, D-BSSE, Biotechnology and Bioengineering Research Group, Basel, CH => Projects: CAR-T cell engineering, closed-loop designer cells for diverse therapies => Work: Project design, gene circuit design, cloning, mammalian cell engineering (HEK293T, JURKAT, MCF7, CTTL-2, K562), flow cytometry, transwell migration assay, ELISA, immunology - ETH Zürich, D-HEST (Department of Health Sciences and Technology), Loessner Group, Zürich, CH => Project 1: Establishment of high-throughput Yeast Surface Display to verify epitopes of deimmunized Peptidoglycan Hydrolases (PGH) fusion proteins for future application against S. aureus infections; => Project 2: Genetic stability study in novel Listeria reporter phages => Work: Python programming, cloning, magnetic bead selections (MACS), flow cytometry; phage propagation (overlay assays...), colony PCR, phenotyping, protocol establishment - Pasteur Institute, BPF team (Biology and Fungal Pathogenicity), Paris => Project: Kinase involvement in Candida glabrata antifungal resistance => Techniques: Yeast cloning, colony PCR, checkerboard assay, PAP assay My studies: MSc from Ecole Normale Supérieure de Lyon (ENS), France => Prestigious French engineering school, World's Best Small Universities 2024 (THE): #1 in France, #7 globally More projects: - iGEM team and project lead - Internationally renowned synthetic biology competition (1 year, 7 members): - Biosciences and Society Forum (ENS Lyon) Group Leader (5 months, 9 members) - Research project leader on desalination using Scenedesmus microalgae (1 year, 4 members) - Conception and presentation of a Molecular Biology workshop, Wyss Zürich BioSTARS camp 2024 - Immunity board game design and interactive lesson at the "Fête de la Science" 2022 Pluridisciplinary background: Strong foundation in maths, physics and chemistry: courses in organic chemistry, thermodyn., biochemistry, and mechanics; specialized training in 2D NMR, X-ray crystallography

専門分野

• ★ Microbiology
• ★ Molecular Cloning
• ★ Bioinformatics
• ☆ Computational Biology
• ☆ Microbiome Research
• ☆ Microbiological Assays
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Transcriptomics
• ☆ PCR
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Plasmid DNA
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cytogenetics
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Data Analysis
• ☆ Data Processing
• ☆ Data Exploration
• ☆ Cluster Analysis
• ☆ Data Visualization
• ☆ Statistics
• ☆ Medical Statistics
• ☆ Health Data Analysis
• ☆ Gene & Protein Expression Analysis
• ☆ Pathogenesis
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Synthetic Biology
• ☆ Biosensors
• ☆ Agricultural Biotechnology
• ☆ Biomolecular Engineering
• ☆ Genetic Engineering
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Python
• ☆ R
• ☆ Clinical Trials
• ☆ Clinical Trials Data Analysis
• ☆ Human Biology
• ☆ Precision Medicine
• ☆ Crohn's Disease
• ☆ Infectious Disease
• ☆ Antibiotic Resistance Research
• ☆ Inflammation
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ SOP & Protocol Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing

Research Feasibility Study, Fact Checking, Scientific and Technical Research

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Processing

Product Development Concept Development

職務経験

PhD student

Institut Pasteur

10月 2025 - 現在

Visiting researcher

University of Oxford

4月 2025 - 現在

Research Intern

Roche

11月 2024 - 4月 2025

Team Leader/Project Manager

iGEM competition

12月 2023 - 10月 2024

Academic guest researcher

ETH Zürich

1月 2024 - 8月 2024

Research Intern

ETH Zürich

2月 2023 - 7月 2023

Resaerch Intern

Institut Pasteur

5月 2022 - 7月 2022

Intern

International Resaerch Center in Infectiology (CIRI, Lyon)

4月 2022 - 5月 2022

学歴

Doctoral Program

Université Paris-Sorbonne (Paris IV) - France

9月 2025 - 現在

Msc (Biosciences)

École normale supérieure de Lyon

2021 - 2025

認定資格

• Formation à l'Expérimentation Animale Niveau Concepteur de projet Ex-NIVEAU I

  Institut Pasteur

  9月 2025 - 現在