この専門家をプロジェクトに採用したいですか? 見積もりを依頼 無料で。
プロフィール詳細
Dr. Tarik R.に依頼
United Kingdom
Freelance Editor Writer & Proofreader with 10+ years experience in translational & clinical research and development
プロフィール概要
専門分野
サービス
Writing
Technical Writing,
Copywriting,
Newswriting,
General Proofreading & Editing
Research
Market Research,
Feasibility Study,
Fact Checking,
Gray Literature Search,
Scientific and Technical Research,
Systematic Literature Review,
Secondary Data Collection
Consulting
Digital Strategy Consulting,
Scientific and Technical Consulting
職務経験
Senior Research Scientist in Molecular and Cellular Cancer Pathology
The John van Great Cancer Research Centre (Nottingham Trent University)
9月 2011 - 8月 2020
Senior Lecturer in Biochemistry
Nottingham Trent University
1月 2010 - 8月 2011
Career Development Fellow in Neurodevelopment and Cancer
MRC Toxicology Unit
7月 2006 - 12月 2009
Research Associate In Neurodevelopment
University of Cambridge (Hudson Institute)
10月 2002 - 6月 2006
学歴
PhD in Cancer Studies
University of Paris 7
10月 1998 - 9月 2002
MSc in Molecular and Cellular Biology
University Paris 7
10月 1996 - 9月 1998
Doctor of Veterinary Medicine
School of Veterinary Medicine (University of Tiaret, Algeria)
10月 1991 - 9月 1996
認定資格
- 認定資格の詳細は未入力です。
出版物
JOURNAL ARTICLE
(2019). PYK2 promotes HER2-positive breast cancer invasion . Journal of Experimental & Clinical Cancer Research.
Barbato L, Bocchetti M, Di Biase A, Regad T(2019). Cancer Stem Cells and Targeting Strategies . Cells.
(2019). Glucose-6-phosphate dehydrogenase blockade potentiates tyrosine kinase inhibitor effect on breast cancer cells through autophagy perturbation . Journal of experimental & clinical cancer research : CR.
Luigi Mele, Francesca Paino, Federica Papaccio, Tarik Regad, David Boocock, Paola Stiuso, Angela Lombardi, Davide Liccardo, Gabriella Aquino, Antonio Barbieri, et al.(2018). A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo . Cell Death {\&} Disease. 9. (5). Springer Nature
Jayakumar Vadakekolathu, Shaymaa Ismael Kadhim Al-Juboori, Catherine Johnson, Anne Schneider, Magdalena Elżbieta Buczek, Anna Di Biase, Alan Graham Pockley, Graham Roy Ball, Desmond George Powe, Tarik Regad(2018). {MTSS}1 and {SCAMP}1 cooperate to prevent invasion in breast cancer . Cell Death {\&} Disease. 9. (3). Springer Nature
Reham M. Balahmar, David J. Boocock, Clare Coveney, Sankalita Ray, Jayakumar Vadakekolathu, Tarik Regad, Selman Ali, Shiva Sivasubramaniam(2018). Identification and characterisation of {NANOG}{\&}{\#}x002B$\mathsemicolon$/ {OCT}-4$\less$sup$\greater$high$\less$/sup$\greater$/{SOX}2{\&}{\#}x002B$\mathsemicolon$ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines . Oncotarget. Impact Journals, {LLC}
Vadakekolathu, J., Al-Juboori, S. I. K., Johnson, C., Schneider, A., Buczek, M. E., Di Biase, A., Pockley, A. G., Ball, G. R., Powe, D. G., Regad, T.(2018). MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer . Cell Death & Disease. 9.
Reham M. Balahmar, David J. Boocock, Clare Coveney, Sankalita Ray, Jayakumar Vadakekolathu, Tarik Regad, Selman Ali, Shiva Sivasubramaniam(2018). Identification and characterisation of NANOG+/ OCT-4<sup>high</sup>/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines . Oncotarget.
Marcella La Noce, Francesca Paino, Luigi Mele, Gianpaolo Papaccio, Tarik Regad, Angela Lombardi, Federica Papaccio, Vincenzo Desiderio, Virginia Tirino(2018). {HDAC}2 depletion promotes osteosarcoma's stemness both in vitro and in vivo: a study on a putative new target for {CSCs} directed therapy . Journal of Experimental {\&} Clinical Cancer Research. 37. (1). Springer Nature
Mele, L., Paino, F., Papaccio, F., Regad, T., Boocock, D., Stiuso, P., Lombardi, A., Liccardo, D., Aquino, G., Barbieri, A., et al.(2018). A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo . Cell Death & Disease. 9.
Federica Papaccio, Francesca Paino, Tarik Regad, Gianpaolo Papaccio, Vincenzo Desiderio, Virginia Tirino(2017). Concise Review: Cancer Cells, Cancer Stem Cells, and Mesenchymal Stem Cells: Influence in Cancer Development . {STEM} {CELLS} Translational Medicine. Wiley-Blackwell
Joshua R D Pearson, Tarik Regad(2017). Targeting cellular pathways in glioblastoma multiforme . Signal Transduction and Targeted Therapy. 2. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 17040. Springer Nature
Tarik Regad(2017). Tissue-specific cancer stem cells: reality or a mirage? . Translational Medicine Reports. 1. (1). {PAGEPress} Publications
Tarik Regad(2017). Tissue-specific cancer stem cells: reality or a mirage? . Translational Medicine Reports. 1. (1).
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A. P., Chayka, O., Regad, T., Pistorio, A., Sementa, A. R., et al.(2017). A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma (vol 22, pg 3398, 2016) . Clinical Cancer Research. 23. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 870.
Joshua R D Pearson, Tarik Regad(2017). Targeting cellular pathways in glioblastoma multiforme . Signal Transduction and Targeted Therapy. 2. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 17040.
Papaccio, F., Paino, F., Regad, T., Papaccio, G., Desiderio, V., Tirino, V.(2017). Concise Review: Cancer Cells, Cancer Stem Cells, and Mesenchymal Stem Cells: Influence in Cancer Development . Stem Cells Translational Medicine. 6. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2115-2125.
Buczek, M.E., Miles, A.K., Green, W., Johnson, C., Boocock, D.J., Pockley, A.G., Rees, R.C., Hulman, G., Van Schalkwyk, G., Parkinson, R., et al.(2016). Cytoplasmic PML promotes TGF-?-associated epithelial-mesenchymal transition and invasion in prostate cancer . Oncogene. 35. (26). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3465-3475.
Buczek, M.E., Miles, A.K., Green, W., Johnson, C., Boocock, D.J., Pockley, A.G., Rees, R.C., Hulman, G., Van Schalkwyk, G., Parkinson, R., et al.(2016). Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer . Oncogene. 35. (26). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3465-3475.
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A. P., Chayka, O., Regad, T., Pistorio, A., Sementa, A. R., et al.(2016). A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma . Clinical Cancer Research. 22. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3398-3409.
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A.P., Chayka, O., Regad, T., Pistorio, A., Sementa, A.R., et al.(2016). A promyelocytic leukemia protein-thrombospondin-2 axis and the risk of relapse in neuroblastoma . Clinical Cancer Research. 22. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3398-3409.
Buczek, M. E., Miles, A. K., Green, W., Johnson, C., Boocock, D. J., Pockley, A. G., Rees, R. C., Hulman, G., van Schalkwyk, G., Parkinson, R., et al.(2015). Role of tumour suppressor PML in prostate cancer progression . International Journal of Molecular Medicine. 36. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString S111.
Regad, T.(2015). Targeting RTK signaling pathways in cancer . Cancers. 7. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1758-1784.
Regad, T.(2015). Targeting RTK Signaling Pathways in Cancer . Cancers. 7. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1758-1784.
Mathieu, M.G., Miles, A.K., Ahmad, M., Buczek, M.E., Pockley, A.G., Rees, R.C., Regad, T.(2014). The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1 . Cell Death and Disease. 5. (2).
Mathieu, M.G., Miles, A.K., Ahmad, M., Buczek, M.E., Pockley, A.G., Rees, R.C., Regad, T.(2014). The helicase HAGE prevents interferon-?-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1 . Cell Death and Disease. 5. (2).
Regad, T.(2013). Molecular and cellular pathogenesis of melanoma initiation and progression . Cellular and Molecular Life Sciences. 70. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4055-4065.
Regad, T.(2013). Molecular and cellular pathogenesis of melanoma initiation and progression . Cellular and Molecular Life Sciences. 70. (21). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4055-4065.
Linley, A. J., Mathieu, M. G., Miles, A. K., Rees, R. C., McArdle, S. E. B., Regad, T.(2012). The Helicase HAGE Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Cell Proliferation in Vivo . Journal of Biological Chemistry. 287. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13633-13643.
McArdle, S. E. B., Linley, A. A. J., Mathieu, M. M. G., Miles, A. A. K., Regad, T., Rees, R. C.(2012). The helicase antigen (HAGE) promotes tumor cell proliferation via up-regulation of Ras protein signalling . Cancer Research. 72.
Linley, A.J., Mathieu, M.G., Miles, A.K., Rees, R.C., McArdle, S.E.B., Regad, T.(2012). The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo . Journal of Biological Chemistry. 287. (17). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13633-13643.
El Mchichi, B., Regad, T., Maroui, M.-A., Rodriguez, M.S., Aminev, A., Gerbaud, S., Escriou, N., Dianoux, L., Chelbi-Alix, M.K.(2010). SUMOylation promotes PML degradation during encephalomyocarditis virus infection . Journal of Virology. 84. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11634-11645.
El Mchichi, Bouchra, Regad, Tarik, Maroui, Mohamed-Ali, Rodriguez, Manuel S., Aminev, Aleksey, Gerbaud, Sylvie, Escriou, Nicolas, Dianoux, Laurent, Chelbi-Alix, Mounira K.(2010). SUMOylation Promotes PML Degradation during Encephalomyocarditis Virus Infection . Journal of Virology. 84. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11634-11645.
Regad, T., Bellodi, C., Nicotera, P., Salomoni, P.(2009). The tumor suppressor Pml regulates cell fate in the developing neocortex . Nature Neuroscience. 12. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 132-140.
Regad, Tarik, Bellodi, Cristian, Nicotera, Pierluigi, Salomoni, Paolo(2009). The tumor suppressor Pml regulates cell fate in the developing neocortex . Nature Neuroscience. 12. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 132-140.
Bouchra M’chichi, Tarik Regad, Laurent Dianoux, Yann Percherancier, Mounira K. Chelbi-Alix(2008). 239 {PML} is cleaved and degraded in {EMCV}-infected cells . Cytokine. 43. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 296. Elsevier {BV}
Bouchra M'chichi, Tarik Regad, Laurent Dianoux, Yann Percherancier, Mounira K. Chelbi-Alix(2008). 239 PML is cleaved and degraded in EMCV-infected cells . Cytokine. 43. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 296.
Regad, T., Roth, M., Bredenkamp, N., Illing, N., Papalopulu, N.(2007). The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF . Nature Cell Biology. 9. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 531-540.
Regad, Tarik, Roth, Martin, Bredenkamp, Nicholas, Illing, Nicola, Papalopulu, Nancy(2007). The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF . Nature Cell Biology. 9. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 531-U87.
Regad, T., Papalopulu, N.(2005). Casein kinase I phosphorylates the forkhead transcription factor FoxG1 and promotes its nuclear localisation . Developmental Biology. 283. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 657.
Tarik Regad, Mounira K. Chelbi-Alix(2002). {PML}, un nouvel interm{\'{e}}diaire de l'effet antiviral de l'interf{\'{e}}ron . m{\'{e}}decine/sciences. 18. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 25--27. {EDP} Sciences
Regad, T, Chelbi-Alix, MK(2002). PML, a mediator of interferon-induced antiviral response . M S-Medecine Sciences. 18. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 25-27.
Blondel, D, Regad, T, Poisson, N, Pavie, B, Harper, F, Pandolfi, PP, de The, H, Chelbi-Alix, MK(2002). Rabies virus P and small P products interact directly with PML and reorganize PML nuclear bodies . Oncogene. 21. (52). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7957-7970.
Blondel, D., Regad, T., Poisson, N., Pavie, B., Harper, F., Pandolfi, P.P., De Thé, H., Chelbi-Alix, M.K.(2002). Rabies virus P and small P products interact directly with PML and reorganize PML nuclear bodies . Oncogene. 21. (52). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7957-7970.
Regad, T., Chelbi-Alix, M.K.(2001). Role and fate of PML nuclear bodies in response to interferon and viral infections . Oncogene. 20. (49 REV. IIS. 6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7274-7286.
Regad, T, Saib, A, Lallemand-Breitenbach, V, Pandolfi, PP, de The, H, Chelbi-Alix, MK(2001). PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator . Embo Journal. 20. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3495-3505.
Regad, T., Saib, A., Lallemand-Breitenbach, V., Pandolfi, P.P., De Thé, H., Chelbi-Alix, M.K.(2001). PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator . EMBO Journal. 20. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3495-3505.
Regad, T., Chelbi-Alix, M.K.(2001). Role and fate of PML nuclear bodies in response to interferon and viral infections . Oncogene. 20. (49 REV. IIS. 6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 7274-7286.
BOOK
Buczek, M.E., Reeder, S.P., Regad, T.(2018). Identification and isolation of cancer stem cells using NANOG-EGFP reporter system . Methods in Molecular Biology. 1692. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 139-148.
Buczek, M.E., Reeder, S.P., Regad, T.(2018). Identification and isolation of cancer stem cells using NANOG-EGFP reporter system . Methods in Molecular Biology. 1692. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 139-148.
Di Biase, A., Miles, A.K., Regad, T.(2018). Generation of in vitro model of epithelial mesenchymal transition (EMT) via the expression of a cytoplasmic mutant form of promylocytic leukemia protein (PML) . Methods in Molecular Biology. 1692. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 129-138.
Di Biase, A., Miles, A.K., Regad, T.(2018). Generation of in vitro model of epithelial mesenchymal transition (EMT) via the expression of a cytoplasmic mutant form of promylocytic leukemia protein (PML) . Methods in Molecular Biology. 1692. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 129-138.
Buczek, M.E., Edwards, J.C., Regad, T.(2015). Prostate Cancer and Prostate Cancer Stem Cells . Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 193-212.
Buczek, M.E., Edwards, J.C., Regad, T.(2015). Prostate Cancer and Prostate Cancer Stem Cells . Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 193-212.
Regad, T., Sayers, T.J., Rees, R.C.(2015). Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics . Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-362.
Regad, T., Sayers, T.J., Rees, R.C.(2015). Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics . Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1-362.
OTHER
Tarik Regad, Morgan G Mathieu(2014). Cancer stem cells ({CSCs}) and epithelial-to-mesenchymal transition ({EMT}): Tumor cell plasticity challenges immunotherapy . 401--414Oxford University Press
Tarik Regad, Morgan G Mathieu(2014). Cancer stem cells (CSCs) and epithelial-to-mesenchymal transition (EMT): Tumor cell plasticity challenges immunotherapy . Tumor Immunology and Immunotherapy. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 401--414.