プロフィール詳細

プロジェクトを作成

★★★★★

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★★★★★

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Dr. Theophilus T.に依頼

United States

PhD Biomedical Scientist | Translational Genomics, Oncology, Endocrinology & Medical Writing

プロフィール概要

PhD Biomedical Scientist with 8 years of postdoctoral experience, including a fellowship at the National Cancer Institute (NIH). I help biotech and pharma teams translate complex molecular and genomics data into clear scientific strategy, medical content, and decision-ready insights. My expertise includes translational genomics, glucocorticoid receptor biology, hormone resistance, CRISPR-Cas9 models, gene regulation, chromatin biology, and NGS workflows including RNA-seq, ChIP-seq, and PRO-seq. I have led and contributed to projects in endocrinology and oncology, including hormone-dependent cancer, glucocorticoid resistance, and tumor biology. I also work with R and Python for data analysis and visualization. I provide support in medical writing, literature review, slide development, study design, protocol optimization, and interpretation of mechanistic and genomics data for research and translational programs. I am especially well suited for projects that require scientific depth, fast turnaround, and clear communication.

専門分野

• ★ Molecular Biology
• ★ Genomics
• ★ Medical Writing
• ☆ Computational Biology
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Binding Assays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Genome Sequencing
• ☆ Mutagenesis
• ☆ Exome Sequencing
• ☆ RNA Synthesis
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ ChIP-Seq
• ☆ Cell Biology
• ☆ Gene Regulation
• ☆ Biophysics
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Cell Line Engineering
• ☆ Biomolecular Engineering
• ☆ Gene Editing/CRISPR
• ☆ Antibody Engineering
• ☆ Blotting
• ☆ Python
• ☆ Matlab
• ☆ Excel
• ☆ LaTex
• ☆ R
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Fact Checking
• ☆ Literature Search
• ☆ Research Summaries & Abstracts
• ☆ Technical & Scientific Writing
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Case Studies
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Grant Writing

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Medical Writing, Technical Writing, Audio Transcription, General Proofreading & Editing

Research Feasibility Study, Fact Checking, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Research Fellow

National Cancer Institute

1月 2020 - 現在

Postgraduate researcher

Stowers Institute for Medical Research

3月 2018 - 1月 2020

学歴

PhD (Life and Biomolecular Sciences)

Open University - ARC Stowers Institute for medical research

6月 2013 - 3月 2018

MSc. Agrobiotechnology (Department of plant breeding)

Justus Liebig Universität Giessen Fachbereich für Agrarwissenschaften Okotrophologie und Umweltmanagement

10月 2009 - 2月 2012

BSc Biochemistry (Biochemistry)

University of Ghana

6月 2004 - 7月 2008

認定資格

• 認定資格の詳細は未入力です。

出版物

PREPRINT

Theophilus T. Tettey, Qizong Lao, Sonal Vaid, Sohyoung Kim, Lyuba Varticovski, Vipula Kolli, Deborah P. Merke, Gordon L. Hager (2025). A Novel Patient-Derived Mutation in Glucocorticoid Receptor Reveals an Essential Role for DNA binding in Development and Endocrine Regulation .

N Nigam, B Bernard, S Kim, K Burkitt, D Tsai, Y Robbins, C Sievers, A Clint, RL Bennett, TT Tettey, et al.(2022). Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck . Cold Spring Harbor Laboratory

JOURNAL ARTICLE

Theophilus T. Tettey, Lorenzo Rinaldi, Gordon L. Hager (2023). Long-range gene regulation in hormone-dependent cancer . Nature Reviews Cancer.

Alba Jiménez-Panizo, Andrea Alegre-Martí, Theophilus T Tettey, Gregory Fettweis, Montserrat Abella, Rosa Antón, Thomas A Johnson, Sohyoung Kim, R Louis Schiltz, Israel Núñez-Barrios, et al.(2022). The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities . Nucleic Acids Research. Oxford University Press ({OUP})

Lorenzo Rinaldi, Gregory Fettweis, Sohyoung Kim, David A. Garcia, Saori Fujiwara, Thomas A. Johnson, Theophilus T. Tettey, Laurent Ozbun, Gianluca Pegoraro, Michele Puglia, et al.(2022). The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation . Science Advances. 8. (13). American Association for the Advancement of Science ({AAAS})

Rinaldi, L., Fettweis, G., Kim, S., Garcia, D.A., Fujiwara, S., Johnson, T.A., Tettey, T.T., Ozbun, L., Pegoraro, G., Puglia, M., et al.(2022). The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation . Science Advances. 8. (13).

(2019). BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential . Science advances.

Miah, S., Banks, C.A.S., Ogunbolude, Y., Bagu, E.T., Berg, J.M., Saraf, A., Tettey, T.T., Hattem, G., Dayebgadoh, G., Kempf, C.G., et al.(2019). BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential . Science Advances. 5. (10).

Tettey, T.T., Gao, X., Shao, W., Li, H., Story, B.A., Chitsazan, A.D., Glaser, R.L., Goode, Z.H., Seidel, C.W., Conaway, R.C., et al.(2019). A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing . Cell Reports. 27. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3770-3779.e7.

OTHER

Jiménez-Panizo, A., Alegre-Martí, A., Fettweis, G., Abella, M., Antón, R., Tettey, T., Schiltz, R.L., Johnson, T.A., Nuñez-Barrios, I., Font-Díaz, J., et al.(2021). The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities . bioRxiv.