プロフィール詳細

プロジェクトを作成

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Dr. Tommaso R.に依頼

Italy

Muscle Metabolism & Aging Specialist | PhD Research Scientist

プロフィール概要

I am a Researcher with a PhD in Food, Health, and Longevity with experience in muscle biology, cellular metabolism, mitochondrial function, oxidative stress, and aging-related processes. My work combines in vitro and in vivo approaches to study muscle atrophy, sarcopenia, cachexia, and AGE-induced metabolic dysfunction, with a strong focus on mitochondrial physiology and cell stress responses. I have contributed to several peer-reviewed publications, including a first-author manuscript currently under revision at Nature Communications on the role of Vitamin D Binding Protein in muscle wasting, and a collaborative study accepted in Nature Metabolism on mitochondrial dysfunction in cancer cachexia. These projects reflect my experience in mechanistic and translational muscle research. My technical skills include: • cell biology and molecular biology (primary and established cell lines, qPCR, western blotting, immunoprecipitation, PLA) • mitochondrial and metabolic assays (Oroboros O2k, ROS measurements, membrane potential, fusion/fission dynamics) • high-resolution microscopy (widefield, confocal, two-photon) • quantitative image analysis (ImageJ/Fiji, AIVIA) • in vivo functional and metabolic assessments (muscle function tests, metabolic phenotyping, tissue processing) I have worked on projects focused on: • mechanisms of muscle atrophy and mitochondrial dysfunction • AGE-mediated muscle degeneration and protection by natural compounds • divergent effects of vitamin D metabolites on muscle cells • muscle-bone crosstalk and aging • nutraceutical interventions targeting sarcopenia and metabolic decline I offer support with: • scientific and medical writing • data analysis and visualization • image analysis and figure preparation • experimental design and troubleshooting • consulting on muscle biology, metabolism, aging, and nutraceuticals

専門分野

• ☆ Analytical Chemistry
• ☆ Molecular Imaging
• ☆ Biostatistics
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Molecular Biology
• ☆ Omics
• ☆ Transcriptomics
• ☆ Proteomics
• ☆ Metabolomics
• ☆ PCR
• ☆ Microinjection
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Neuroscience
• ☆ Neurophysiology
• ☆ Behavioral Neuroscience
• ☆ Cognitive Neuroscience
• ☆ Neuroanatomy
• ☆ Histology
• ☆ Biotechnology & Bioengineering
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Data Analysis
• ☆ Image Processing
• ☆ Social Network Analysis
• ☆ Data Processing
• ☆ Data Visualization
• ☆ Data Collection
• ☆ Data Management
• ☆ Data Manipulation
• ☆ Data Cleaning
• ☆ Artificial Intelligence
• ☆ Statistics
• ☆ Comparative Analysis
• ☆ Meta-Analysis
• ☆ Nonlinear Regression
• ☆ Study Design
• ☆ Statistical Review
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Surface Receptors
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Tissue Engineering
• ☆ Cell Aging

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Technical Writing, Newswriting, General Proofreading & Editing

Research Technology Scouting, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Processing, Image Analysis, Data Visualization, Data Mining, Data Cleaning, Data Processing

職務経験

Postdoctoral researcher

University of Perugia

5月 2024 - 現在

PhD student

Università degli Studi del Piemonte Orientale Amedeo Avogadro Dipartimento di Medicina Traslazionale

11月 2021 - 1月 2024

学歴

PhD in Food, Health and Longevity

University of Piemonte Orientale, Novara, Italy

11月 2020 - 1月 2024

Master’s Degree in Medical Biotechnologies

University of Piemonte Orientale, Novara, Italy

10月 2018 - 7月 2020

Bachelor’s Degree in Biotechnologies

University of Piemonte Orientale, Novara, Italy

10月 2015 - 10月 2018

認定資格

• Advanced Scientific English. Grant Writing & Oral Presentation

  American Business English School

  7月 2023 - 現在

• Basic Biology, Euthanasia and Minimally Invasive Procedures in Mice

  Charles River Training Program

  1月 2023 - 現在

• Biology and Management of Laboratory Animals

  Istituto Zooprofilattico Sperimentale Lombardia & Emilia Romagna

  7月 2022 - 現在

• Ethics and Project Management in Animal Research

  Istituto Zooprofilattico Sperimentale Lombardia & Emilia Romagna

  7月 2022 - 現在

• Scientific English Writing Course

  American Business English School

  7月 2022 - 現在

• National Legislation and Ethics for Laboratory Animal Research

  stituto Zooprofilattico Sperimentale Lombardia & Emilia Romagna

  6月 2022 - 現在

出版物

JOURNAL ARTICLE

Tommaso Raiteri, Martina Paiella, Simone Reano, Dominga Manfredelli, Tommaso Manenti, Giulia Gentili, Hajar Meskine, Sara Chiappalupi, Giovanni Bellomo, Flavia Prodam, et al. (2025). Diet-Derived Advanced Glycation End-Products (AGEs) Induce Muscle Wasting In Vitro, and a Standardized Vaccinium macrocarpon Extract Restrains AGE Formation and AGE-Dependent C2C12 Myotube Atrophy . Antioxidants.

Tommaso Raiteri, Martina Paiella, Simone Reano, Dominga Manfredelli, Tommaso Manenti, Giulia Gentili, Hajar Meskine, Sara Chiappalupi, Giovanni Bellomo, Flavia Prodam, et al. (2025). Diet-Derived Advanced Glycation End-Products (AGEs) Induce Muscle Wasting In Vitro, and a Standardized <i>Vaccinium macrocarpon</i> Extract Restrains AGE Formation and AGE-Dependent C2C12 Myotube Atrophy . Antioxidants.

Tommaso Raiteri, Ivan Zaggia, Simone Reano, Andrea Scircoli, Laura Salvadori, Flavia Prodam, Nicoletta Filigheddu (2021). The Atrophic Effect of 1,25(OH)2 Vitamin D3 (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress . Antioxidants.

Tommaso Raiteri, Ivan Zaggia, Simone Reano, Andrea Scircoli, Laura Salvadori, Flavia Prodam, Nicoletta Filigheddu (2021). The Atrophic Effect of 1,25(OH)₂ Vitamin D₃ (Calcitriol) on C2C12 Myotubes Depends on Oxidative Stress . Antioxidants.

Maraiza Alves Teixeira and Marilisa De Feudis and Simone Reano and Tommaso Raiteri and Andrea Scircoli and Ivan Zaggia and Sara Ruga and Laura Salvadori and Flavia Prodam and Paolo Marzullo and Claudio Molinari and Davide Cor{\`{a}} and Nicoletta Filigheddu(2021). Cholecalciferol (vitamin D3) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes . Aging. 13. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4895--4910. Impact Journals, {LLC}

Raiteri, T., Zaggia, I., Reano, S., Scircoli, A., Salvadori, L., Prodam, F., Filigheddu, N.(2021). The atrophic effect of 1,25(Oh)₂ vitamin d₃ (calcitriol) on c2c12 myotubes depends on oxidative stress . Antioxidants. 10. (12).

Teixeira, M.A., Feudis, M.D., Reano, S., Raiteri, T., Scircoli, A., Zaggia, I., Ruga, S., Salvadori, L., Prodam, F., Marzullo, P., et al.(2021). Cholecalciferol (vitamin D₃) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes . Aging. 13. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4895-4910.

Emanuela Agosti and Marilisa De Feudis and Elia Angelino and Roberta Belli and Maraiza Alves Teixeira and Ivan Zaggia and Edoardo Tamiso and Tommaso Raiteri and Andrea Scircoli and Flavio L. Ronzoni and Maurizio Muscaritoli and Andrea Graziani and Flavia Prodam and Maurilio Sampaolesi and Paola Costelli and Elisabetta Ferraro and Simone Reano and Nicoletta Filigheddu(2020). Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice . Aging. 12. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13939--13957. Impact Journals, {LLC}

Agosti, E., Feudis, M.D., Angelino, E., Belli, R., Teixeira, M.A., Zaggia, I., Tamiso, E., Raiteri, T., Scircoli, A., Ronzoni, F.L., et al.(2020). Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice . Aging. 12. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 13939-13957.