プロフィール詳細

プロジェクトを作成

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Dr. UKSHA S.に依頼

United States

In Vivo Oncology and Pharmacology Consultant | Preclinical Research | Animal Models and Drug Development

プロフィール概要

Highly motivated researcher with multidisciplinary experience, a strong background in in vitro and in vivo aspects of immunomodulation drug discovery. 13 years of hands-on expertise in cell based functional bioassay development, immunology, stem cell biology, CDX, PDX mouse orthotopic solid and hematologic tumor models, ADME and PK/PD studies, target validation, pre clinical and clinical development and IND enabling studies.

専門分野

• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ PCR
• ☆ Molecular Cloning
• ☆ DNA Damage & Repair
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Neuroscience
• ☆ Molecular Neuroscience
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Microscopy
• ☆ Fluorescence Microscopy
• ☆ Biomarker Discovery
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Survey Design & Methodology
• ☆ Medical Writing
• ☆ Research Summaries & Abstracts
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Case Studies
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Grant Writing

サービス

• Writing
• Research

Writing Clinical Trial Documentation, Medical Writing, Technical Writing

Research User Research

職務経験

Senior Scientist / Group Manager

Fannin Innovation Studio

8月 2022 - 現在

Biologist/Research Scientist

Nationwide Children's Hospital

8月 2018 - 6月 2022

PostdoctoralResearcher

Ohio State University

3月 2011 - 8月 2018

PostdoctoralResearcher

Bowling Green State University

8月 2008 - 12月 2010

学歴

PhD in Biotechnology

IHBT, PALAMPUR, INDIA

3月 2002 - 2月 2008

認定資格

• immunoinformatics

  udemy

  https://www.udemy.com/certificate/UC-7aece5f8-1f1b-4722-83fb-19f3ea6d42a5/

  1月 2025 - 現在

出版物

JOURNAL ARTICLE

Ghonime MG, Saini U, Kelly MC, Roth JC, Wang PY, Chen CY, Miller K, Hernandez-Aguirre I, Kim Y, Mo X, et al. (2021). Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy . Journal for immunotherapy of cancer.

Dorayappan KDP, Wanner R, John J. Wallbillich, Saini U, Zingarelli R, Suarez AA, Cohn DE, Selvendiran K (2018). Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins . Oncogene.

Saini U, Naidu S, A. C. ElNaggar, Bid HK, John J. Wallbillich, Bixel K, Bolyard C, Suarez AA, Balveen Kaur, Kuppusamy P, et al. (2016). Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target . Oncogene.

Saini U, Gumina RJ, Wolfe B, Kuppusamy ML, Kuppusamy P, Boudoulas KD (2013). Preconditioning mesenchymal stem cells with caspase inhibition and hyperoxia prior to hypoxia exposure increases cell proliferation . Journal of cellular biochemistry.