プロフィール詳細

プロジェクトを作成

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Dr. Umberto A.に依頼

Italy

Molecular Biology & Genomics Consultant | Experimental Design, Grant Writing & Reviews | Ph.D. & Stanford Postdoc

プロフィール概要

I am a molecular biologist and geneticist with over 8 years of research experience at leading international institutions, including postdoctoral work at Stanford University School of Medicine and a Ph.D. from Université Paris Cité. My research focuses on RNA biology, genome stability, gene expression, CRISPR, and synthetic biology with peer-reviewed publications in top-tier journals including Molecular Cell, EMBO Journal, and Science Advances. I offer expert consulting services in three key areas: Experimental design & methodology — helping researchers and biotech companies build robust, reproducible study protocols Grant writing & research strategy — supporting academics and startups in securing competitive funding Systematic reviews & literature research — delivering rigorous, publication-ready scientific syntheses Having worked across Italy, France, Spain, and the USA, I am fully comfortable operating in international, remote-first environments and collaborating with clients across time zones. Whether you are a researcher looking to strengthen your methodology, a startup navigating the funding landscape, or a company needing scientific expertise, I am here to help you achieve your goals with precision and clarity.

専門分野

• ☆ Computational Biology
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Transcriptomics
• ☆ Genomics
• ☆ Chromatin
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Next Generation Sequencing (NGS)
• ☆ DNA Sequencing
• ☆ Synthetic Genomics
• ☆ Genome Sequencing
• ☆ Mutagenesis
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ ChIP-Seq
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ R
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Grant Writing

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, Creative Writing, General Proofreading & Editing, Translation

Research Feasibility Study, Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis

職務経験

postdoctoral scholar

Stanford University

9月 2022 - 現在

PhD fellow

Centre National de la Recherche Scientifique

8月 2017 - 6月 2022

学歴

PhD

Université Paris Cité

10月 2017 - 12月 2021

認定資格

• 認定資格の詳細は未入力です。

出版物

PREPRINT

Umberto Aiello, Kevin R. Roy, Lars M. Steinmetz (2025). Mutational scanning by multiplexed genome editing of the essential transcription termination factor Nrd1 .

JOURNAL ARTICLE

Aiello, Umberto, Porrua, Odil, Libri, Domenico(2024). Sen1: the varied virtues of a multifaceted helicase . Journal of molecular biology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 168808.

Umberto Aiello, Jonathan Heuzé, Samira Kemiha, Antoine Barthe, Alba Torán Vilarrubias, Elyès Aouadi, Domenico Libri, Yea-Lih Lin, Armelle LENGRONNE, Jérôme Poli, et al.(2023). RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart . The EMBO Journal. {EMBO}

Umberto Aiello, Jonathan Heuzé, Samira Kemiha, Antoine Barthe, Alba Torán Vilarrubias, Elyès Aouadi, Domenico Libri, Yea-Lih L Lin, Armelle Lengronne, Jérôme Poli, et al.(2023). RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart . The EMBO journal. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString e113104.

Umberto Aiello, Heta P Patel, Stefano Coppola, Wim Pomp, Ineke Brouwer, Domenico Libri, Tineke L Lenstra(2023). DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes . Molecular cell. 83. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1573–1587.e8.

Umberto Aiello, Heta P. Patel, Stefano Coppola, Wim Pomp, Ineke Brouwer, Domenico Libri, Tineke L. Lenstra(2023). DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes . Molecular Cell. 83. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1573--1587.e8. Elsevier {BV}

Umberto Aiello, Juanjuan Xie, Yves Clement, Nouhou Haidara, Mathias Girbig, Jana Schmitzova, Vladimir Pena, Christoph W. Müller, Domenico Libri, Odil Porrua (2022). An integrated model for termination of RNA polymerase III transcription . Science Advances.

Umberto Aiello, Juanjuan Xie, Yves Clement, Nouhou Haidara, Mathias Girbig, Jana Schmitzova, Vladimir Pena, Christoph W Müller, Domenico Libri, Odil Porrua(2022). An integrated model for termination of RNA polymerase III transcription . Science advances. 8. (28). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString eabm9875.

Umberto Aiello, Drice Challal, Griselda Wentzinger, Armelle Lengronne, Rowin Appanah, Philippe Pasero, Benoit Palancade, Domenico Libri(2022). Sen1 is a key regulator of transcription-driven conflicts . Molecular cell.

Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability @article{appanah_lones_aiello_libri_de piccoli_2020, title={Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability}, volume={30}, number={7}, journal={CELL REPORTS}, publisher={CELL PRESS}, author={Appanah, Rowin and Lones, Emma Claire and Aiello, Umberto and Libri, Domenico and De Piccoli, Giacomo}, year={2020}, pages={2094–2105}} . CELL REPORTS.

REVIEW

Umberto Aiello, Odil Porrua, Domenico Libri (2024). Sen1: the varied virtues of a multifaceted helicase . Journal of Molecular Biology.

OTHER

Meet the authors: Umberto Aiello and Domenico Libri @article{2022, doi = {10.1016/j.molcel.2022.07.018}, url = {https://doi.org/10.1016%2Fj.molcel.2022.07.018}, year = 2022, month = {aug}, publisher = {Elsevier {BV}}, volume = {82}, number = {16}, pages = {2913--2915}, title = {Meet the authors: Umberto Aiello and Domenico Libri}, journal = {Molecular Cell}} . Molecular Cell.