プロフィール詳細

プロジェクトを作成

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Dr. Valeria P.に依頼

United Kingdom

Skilled scientist researcher (medical) with over 12+ of experience in the field of regenerative medicine and devices

プロフィール概要

Within the multidisciplinary field of regenerative medicine, my specific research interests lie in two interconnected areas including tissue engineering and stem cell biology. In tissue engineering, I encourage basic and translational research that takes advantage of advances in biology, chemistry, material science and nanotechnology to develop new constructs capable to mimic the structure and function of organs and tissues targeted for their regeneration and repair both in vitro and in vivo. This research is closely associated with the use of specific synthetic and processing methods to rationally design and create biomaterials in according to their final clinical and therapeutic applications including diabetes, osteoporosis and neurodegenerative diseases. In stem cell biology, I am focus in the development of adult stem cell-derived organoid systems to serve as a new class of biological model for both tissue and organ proxies. These generally aim to recapitulate the main natural features of the stem cell microenvironment or niche which strictly include cell-environment interactions, cell-cell contacts and certain physiological cues generated by tissue-specific cells within the organoid.

専門分野

• ★ Nanotechnology & Nanomaterials
• ★ Molecular Biology
• ★ Biomedical Engineering
• ☆ STEM
• ☆ Surface Science
• ☆ Nanotechnology
• ☆ Immunoassay
• ☆ Structural Biology
• ☆ Biomarkers
• ☆ Nanobiotechnology
• ☆ Cell Aging
• ☆ Small Molecule Drug Development
• ☆ Medical Sciences
• ☆ Research Methodology
• ☆ Technical & Scientific Writing

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, Copywriting, Newswriting

Research User Research, Gap Analysis, Systematic Literature Review

Consulting Scientific and Technical Consulting

職務経験

Academic (Casual)

Medical Writer and Consultant

1月 2016 - 現在

Researcher

University of Brighton

12月 2014 - 現在

Scientific Researcher

University of Brighton

12月 2014 - 現在

学歴

PhD in Biomedical Engineering

University of Brighton

10月 2009 - 1月 2014

PhD (School of Pharmacy and Biomolecular Sciences)

University of Brighton

10月 2009 - 1月 2014

認定資格

• JPE Doctoral Research Award in Biomaterials

  European Society of Biomaterials

  4月 2014 - 現在

出版物

JOURNAL ARTICLE

ANTI-ANGIOGENIC POTENTIAL OF VEGF BLOCKER DENDRON-LADEN GELLAN GUM HYDROGELS FOR TISSUE ENGINEERING APPLICATIONS. J TISSUE ENG REGEN MED. 2016, DOI: 10.1002/TERM.2340.

A comparative in vitro study of the effect of biospecific integrin recognition processes and substrate nanostructure on stem cell 3D spheroid formation. J Mater Sci Mater Med, 31(4):37, 23 Mar 2020.

Anti-angiogenic potential of VEGF blocker dendron loaded on to gellan gum hydrogels for tissue engineering applications. J Tissue Eng Regen Med, 12(2):e669-e678, 30 Mar 2017.

A Substrate-Mimicking Basement Membrane Drives the Organization of Human Mesenchymal Stromal Cells and Endothelial Cells Into Perivascular Niche-Like Structures. Front Cell Dev Biol, 9:701842, 28 Sep 2021.

Carboxybetaine-modified succinylated chitosan-based beads encourage pancreatic β-cells (Min-6) to form islet-like spheroids under in vitro conditions. J Mater Sci Mater Med, 29(1):15, 30 Dec 2017.

Hyperbranched poly(ϵ-lysine) substrate presenting the laminin sequence YIGSR induces the formation of spheroids in adult bone marrow stem cells. PLoS One, 12(12):e0187182, 12 Dec 2017.

EVIDENCE FOR A ROLE OF TGF-Β1 IN THE EXPRESSION AND REGULATION OF Α-SMA IN FETAL GROWTH RESTRICTED PLACENTAE. PLACENTA. 2007, 28(11-12):1123-32.

Vascular Endothelial Growth Factor Sequestration Enhances In Vivo Cartilage Formation. Int J Mol Sci, 18(11), 21 Nov 2017.

In vivo biofunctional evaluation of hydrogels for disc regeneration. Eur Spine J, 23(1):19-26, 01 Jan 2014.

SILVERDOPED SELF-ASSEMBLING DIPHENYLALANINE HYDROGELS AS WOUND DRESSING BIOMATERIALS. J MATER SCI: MATER MED. 2013, DOI:10.1007/S10856-013-4986-2.

Synthesis, characterisation and in vitro anti-angiogenic potential of dendron VEGF blockers. Macromol Biosci, 11(12):1761-1765, 23 Nov 2011.

CONFERENCE PAPER

CARDIAC TISSUE REGENERATION. J ENDOVASCUL THERAPY 2011. 18 SUPPLEMENT I PG(S) E11-E12.

DENDRITIC VEGF BLOCKERS TO CONTROL ANGIOGENESIS IN TISSUE REGENERATION. J TISSUE ENG REGEN MED. 2012, 6 (SUPPL. 1): 300.

JOURNAL ISSUE

SYNTHETIC NICHE-MIMICKING SUBSTRATES FOR THE PRECLINICAL HANDLING OF STEM CELLS. REGEN MED J. 2013, 8:6-126.