プロフィール詳細

プロジェクトを作成

★★★★★

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★★★★★

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Dr. Wulin T.に依頼

Canada

Imaging Scientist | Biochemical Imaging and Machine Learning Data Scientist

プロフィール概要

I am a highly skilled Imaging Scientist and Data Scientist with a Ph.D. in neuroscience and over a decade of experience in cutting-edge research. My expertise spans optical microscopy, biochemical imaging, machine learning, and advanced data analysis, with a strong focus on multidimensional data segmentation involving spatial (XYZ), spectral (λ), and temporal (τ) dimensions. I have led innovative projects in myelin and lipid research, developing novel methodologies such as spectral microscopy using solvatochromic dyes to uncover biochemical abnormalities. My experience includes 2D and 3D image analysis of large datasets, implementing machine learning techniques for segmentation and prediction, and creating pipelines for handling complex imaging data. With a proven track record of publications in high-impact journals like PNAS and the Journal of Neurochemistry, I have honed my ability to solve complex problems and communicate findings effectively. My collaborative work spans academic institutions and potential industrial applications, particularly in optical microscopy, imaging data analytics, and biochemical research. I am passionate about translating scientific innovations into industrial solutions and am eager to contribute my skills to diverse projects in optical microscopy, imaging data analysis, and machine learning-driven insights.

専門分野

• ★ Spectroscopy
• ★ Neurochemistry
• ★ Machine Learning
• ☆ Analytical Chemistry
• ☆ Petrochemistry
• ☆ Microbiology
• ☆ Virology
• ☆ Molecular Virology
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Protein Sequencing
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ DNA/Gene Synthesis
• ☆ Cell Biology
• ☆ Cytochemistry
• ☆ Neuroscience
• ☆ Neuroanatomy
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Scanning Probe Microscopy
• ☆ Statistics
• ☆ Regression Analysis
• ☆ Multivariate Analysis
• ☆ Nonlinear Regression
• ☆ Bioinformatics
• ☆ Gene & Protein Expression Analysis
• ☆ Immunohistochemistry
• ☆ Data Storage
• ☆ Python
• ☆ Sclerosis & Demyelinating Diseases

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing

Research User Research, Scientific and Technical Research, Systematic Literature Review

Consulting Digital Strategy Consulting, Healthcare Consulting, Operations Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-ML, Data Visualization, Big Data Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights

職務経験

Research Assocaite

University of Calgary

7月 2020 - 2月 2025

Image Analysis Specialist

Department of Cell Biology and Neurology, Emory University

1月 2006 - 8月 2007

学歴

Postdoctoral Fellow

University of Calgary

5月 2015 - 7月 2020

Ph.D. in Neuroscience

University of Calgary

9月 2007 - 5月 2015

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

W. Teo, M. L. Morgan, pstys (2025). Quantitation of the physicochemical properties of myelin using Nile Red fluorescence spectroscopy . Journal of Neurochemistry.

Megan Morgan, Teo W, Hernandez Y, Brideau C, Cummins K, Kuipers HF, Stys PK (2022). Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper . ASN neuro.

(2021). Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity . Proceedings of the National Academy of Sciences of the United States of America.

(2020). Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination . The Journal of neuroscience : the official journal of the Society for Neuroscience.

Wulin Teo, Joey Grochmal, Hardeep Gambhir, Ranjan Kumar, Jo Anne Stratton, Raveena Dhaliwal, Craig Brideau, Jeff Biernaskie, Peter Stys, Rajiv Midha(2020). Spectral Characterization of Stem Cell-Derived Myelination within the Injured Adult PNS Using the Solvatochromic Dye Nile Red . Cells. 9. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 189. {MDPI} {AG}

Wulin Teo, Joey Grochmal, Hardeep Gambhir, Ranjan Kumar, Jo Anne Stratton, Raveena Dhaliwal, Craig Brideau, Jeff Biernaskie, Peter Stys, Rajiv Midha (2020). Spectral Characterization of Stem Cell-Derived Myelination within the Injured Adult PNS Using the Solvatochromic Dye Nile Red . Cells.

(2018). Deficient Surveillance and Phagocytic Activity of Myeloid Cells Within Demyelinated Lesions in Aging Mice Visualized by Ex Vivo Live Multiphoton Imaging . The Journal of neuroscience : the official journal of the Society for Neuroscience.

(2018). A novel approach to 32-channel peripheral nervous system myelin imaging in vivo, with single axon resolution . Journal of neurosurgery.

(2017). Mechanisms of lysophosphatidylcholine-induced demyelination: A primary lipid disrupting myelinopathy . Glia.

(2013). Toll-like receptor 2-mediated alternative activation of microglia is protective after spinal cord injury . Brain : a journal of neurology.

(2012). Titration of feline immunodeficiency virus-based lentiviral vector preparations . Cold Spring Harbor protocols.

(2012). Feline immunodeficiency virus-based lentiviral vectors . Cold Spring Harbor protocols.

(2012). Production and harvest of feline immunodeficiency virus-based lentiviral vector from cells grown in T75 tissue-culture flasks . Cold Spring Harbor protocols.

(2012). Production, harvest, and concentration of feline immunodeficiency virus-based lentiviral vector from cells grown in CF10 or CF2 devices . Cold Spring Harbor protocols.

(2009). Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates . Human gene therapy.

(2007). Durable, safe, multi-gene lentiviral vector expression in feline trabecular meshwork . Molecular therapy : the journal of the American Society of Gene Therapy.

(2006). An essential role for LEDGF/p75 in HIV integration . Science (New York, N.Y.).

(2006). Perfusion of his-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor . Investigative ophthalmology & visual science.

(2005). Restriction of feline immunodeficiency virus by Ref1, Lv1, and primate TRIM5alpha proteins . Journal of virology.

(2004). Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo . Investigative ophthalmology & visual science.

(2004). Long-term retinal transgene expression with FIV versus adenoviral vectors. Molecular vision.

(2003). Comparison of wild-type and class I integrase mutant-FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium . The journal of gene medicine.

(2002). Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. Investigative ophthalmology & visual science.