level-one heading

プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Dr. XI W.に依頼

United States

プロフィール概要

Current research - To decipher the molecular mechanisms responsible for productive or defective immune responses against chronic diseases like cancer and exploit knowledge to design effective therapeutic strategies with potential clinical applications. Including: 1. Mechanism of immune surveillance and suppression in cancer. 2. Engineering immune cells against cancer. 3. Engineering stem cells against cancer Previous research - 1. Cell death in tumor and heart. 2. Explore the mechanisms of immune suppression and evasion related to Epstein-Barr virus infection. 3. Clinical characteristics and genetic profiles of patients with severe combined immunodeficiency disease.

専門分野

• ★ Molecular Biology
• ☆ Biochemistry
• ☆ Stem Cell Research
• ☆ Surveillance Systems
• ☆ Epstein-Barr Virus (EBV)
• ☆ Cancer Research

サービス

• Writing
• Consulting
• Data & AI
• Product Development

職務経験

Postdoctoral fellow

UCLA

5月 2015 - 現在

Postdoctoral fellow

UCLA

5月 2015 - 現在

Postdoctoral Fellow

University of California Los Angeles

5月 2015 - 現在

Postdoctoral fellow

St. Jude Children's Research Hospital

12月 2014 - 5月 2015

Postdoctoral fellow

St. Jude Children's Research Hospital

12月 2014 - 5月 2015

Postdoctoral Fellow

St. Jude Children's Research Hospital

12月 2014 - 4月 2015

学歴

Ph.D.

University of Tennessee Health Science Center

8月 2008 - 12月 2014

Ph.D. (College of Graduate Science/IPBS)

University of Tennessee Health Science Center

8月 2008 - 12月 2014

Master of Medicine

Shanghai Jiaotong University Medical School

9月 2004 - 7月 2007

Master of Medicine (Pediatrics)

Shanghai Jiaotong University School of Medicine Xinhua Hospital

9月 2004 - 7月 2007

Bachelor of Medicine

Chongqing Medical School

9月 1999 - 7月 2004

Bachelor of Medicine (Pediatrics)

Chongqing Medical University

9月 1999 - 7月 2004

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

(2019). Creatine uptake regulates CD8 T cell antitumor immunity . The Journal of experimental medicine.

(2019). Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer . Cell stem cell.

Li, B., Wang, X., Choi, I.Y., Wang, Y.-C., Liu, S., Pham, A.T., Moon, H., Smith, D.J., Rao, D.S., Boldin, M.P., et al.(2017). MIR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity . Journal of Clinical Investigation. 127. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3702-3716.

Xi Wang, Drake J. Smith, Levina J. Lin, Heesung Moon, Alexander T. Pham, Siyuan Liu, Sunjong Ji, Valerie Rezek, Saki Shimizu, Marlene Ruiz, et al.(2016). Propagating Humanized {BLT} Mice for the Study of Human Immunology and Immunotherapy . Stem Cells and Development. 25. (24). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1863--1873. Mary Ann Liebert Inc

X. Li-Harms, S. Milasta, J. Lynch, C. Wright, A. Joshi, R. Iyengar, G. Neale, X. Wang, Y.-D. Wang, T. A. Prolla, et al.(2014). Mito-protective autophagy is impaired in erythroid cells of aged {mtDNA}-mutator mice . Blood. 125. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 162--174. American Society of Hematology

Xi Wang, Ying-Ying Jin, Jing Du, Rui-Ming Cao, Helen K.W. Law, Juan-Juan Wang, Tong-Xin Chen(2014). Epstein{\textendash}Barr virus induces the differentiation of semi-mature dendritic cells from cord blood monocytes . Human Immunology. 75. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 306--316. Elsevier {BV}

X. Wang, M. Bathina, J. Lynch, B. Koss, C. Calabrese, S. Frase, J. D. Schuetz, J. E. Rehg, J. T. Opferman(2013). Deletion of {MCL}-1 causes lethal cardiac failure and mitochondrial dysfunction . Genes {\&} Development. 27. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1351--1364. Cold Spring Harbor Laboratory Press

Xi Wang, Juan-Juan Wang, Yu-Feng Li, Ying-Ying Jin, Tong-Xin Chen(2012). Effects of Epstein-Barr virus on the development of dendritic cells derived from cord blood monocytes: an essential role for apoptosis . The Brazilian Journal of Infectious Diseases. 16. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 19--26. Elsevier {BV}

Xi Wang, Chun-Mei Yao, Xiao-Hua Han, Yi-Dan Zhang, Hui Zhang, Ying-Ying Jin, Rui-Ming Cao, Quan-Hua Liu, Wei Zhao, Tong-Xin Chen(2012). Clinical Characteristics and Genetic Profiles of 44 Patients with Severe Combined Immunodeficiency ({SCID}): Report from Shanghai, China (2004{\textendash}2011) . Journal of Clinical Immunology. 33. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 526--539. Springer Nature

Xi Wang, Lin-Lin Wang, Ying-Ying Jin, Yi-Qun Hao, Juan-Juan Wang, Chun-Mei Yao, Rui-Ming Cao, Hui Zhang, Yi Chen, Tong-Xin Chen(2011). Distribution and Clinical Features of Primary Immunodeficiency Diseases in Chinese Children (2004{\textendash}2009) . Journal of Clinical Immunology. 31. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 297--308. Springer Nature