プロフィール詳細

プロジェクトを作成

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Yen-Ju L.に依頼

Germany

Immunology & Cancer Biology Specialist | Study Design | Scientific Writing, Data Analysis & Interpretation

プロフィール概要

I am a senior immunologist and cancer biology researcher with over 14 years of extensive experience across both academia and the biotechnology industry. My background includes designing, leading, and supporting preclinical projects involving the evaluation of novel therapeutic strategies, immune modulation, and functional immunology assays. I have developed and optimized biologics-related in vitro and in vivo workflows, collaborated with multidisciplinary teams, and delivered data-driven scientific recommendations. In addition to research and experimental design, I have strong experience in scientific writing, including literature reviews, research summaries, study protocols, and manuscript preparation. Throughout my academic career, I have published over 10 peer-reviewed articles, including first-author papers. I am skilled at translating complex scientific concepts into clear, accurate, and well-structured documents suitable for researchers, biotech companies, and early-stage startups. I am particularly experienced in: - Preclinical functional study design, optimization, validation, and data analysis & interpretation - Immunology and oncology research support - Scientific writing (reviews, reports, protocols, and manuscripts) - Experimental troubleshooting and strategic project planning - Cross-functional communication between academic and industry teams I aim to provide reliable, detail-oriented scientific support to clients who need expertise in immunology, preclinical models, and high-quality scientific communication.

専門分野

• ★ Preclinical Research
• ★ Immunotherapy
• ★ Technical & Scientific Writing
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Adjuvant & Antigen Research
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Banking
• ☆ Cell Line Engineering
• ☆ Biomolecular Engineering
• ☆ Gene Editing/CRISPR
• ☆ Gene Delivery
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Bioanalytical Testing
• ☆ Vaccine Development
• ☆ Hypothesis
• ☆ Research Methodology
• ☆ Graphic Design
• ☆ Journal Selection
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Textbook Content Writing
• ☆ Science Communication
• ☆ Literature Review
• ☆ Traditional/Narrative Literature Review
• ☆ Systematic Literature Review
• ☆ Scientific Proofreading & Editing
• ☆ Proofreading & Editing
• ☆ Grant Writing

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Audio Transcription, General Proofreading & Editing, Translation

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Data Visualization

職務経験

Postdoctoral researcher

Helmholtz Institute for Translational Oncology Mainz (HI-TRON Mainz) – A Helmholtz Institute of the

1月 2025 - 11月 2025

PhD student

Paul-Ehrlich-Institut

3月 2019 - 11月 2022

National Taiwan University

9月 2017 - 1月 2019

Associate Scientist

UBI Pharma Inc. (UBIP)

3月 2015 - 11月 2016

Research Associate

United Biomedical, Inc. Asia (UBIA)

2月 2013 - 3月 2015

学歴

Doctor rerum naturalium (Dr. rer. nat.)

Technische Universität Darmstadt

3月 2019 - 9月 2022

Master student (Physiology)

National Yang-Ming University

9月 2010 - 8月 2012

Bachelor student (Life Sciences)

National Chung Hsing University

9月 2006 - 6月 2010

認定資格

• 認定資格の詳細は未入力です。

出版物

JOURNAL ARTICLE

Yen-Ju Lin, Hannah Rainer, Alexandra Goretzki, Hannah Ruth Schiller, Maren Krause, Sascha Döring, Daniel Strecker, Ann-Christine Junker, Sonja Wolfheimer, Masako Toda, et al. (2024). Characterization of the Immune-Modulating Properties of Different β-Glucans on Myeloid Dendritic Cells . International Journal of Molecular Sciences.

Yen-Ju Lin, Hannah Rainer, Alexandra Goretzki, Hannah Ruth Schiller, Maren Krause, Sascha Döring, Daniel Strecker, Ann-Christine Junker, Sonja Wolfheimer, Masako Toda, et al. (2024). Characterization of the Immune-Modulating Properties of Different β-Glucans on Myeloid Dendritic Cells . International Journal of Molecular Sciences.

Lin YJ, Zimmermann J, Schülke S (2024). Novel adjuvants in allergen-specific immunotherapy: where do we stand? . Frontiers in immunology.

Lin YJ, Jamin A, Wolfheimer S, Fiedler A, Junker AC, Goretzki A, Scheurer S, Schülke S (2023). A flagellin-conjugate protein induces dual NLRC4- and NLRP3-inflammasome activation which modulates inflammatory cytokine secretion from macrophages . Frontiers in immunology.

Lin YJ, Goretzki A, Rainer H, Zimmermann J, Schülke S (2022). Immune Metabolism in TH2 Responses: New Opportunities to Improve Allergy Treatment - Cell Type-Specific Findings (Part 2) . Current allergy and asthma reports.

Goretzki A, Zimmermann J, Rainer H, Lin YJ, Schülke S (2022). Immune Metabolism in TH2 Responses: New Opportunities to Improve Allergy Treatment - Disease-Specific Findings (Part 1) . Current allergy and asthma reports.

Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> . International Journal of Molecular Sciences.

Goretzki A, Lin YJ, Meier C, Dorn B, Wolfheimer S, Jamin A, Schott M, Wangorsch A, Vieths S, Jakob T, et al. (2022). Stimulation of naïve B cells with a fusion protein consisting of FlaA and Bet v 1 induces regulatory B cells ex vivo . Allergy.

Yen-Ju Lin, Alexandra Goretzki, Jennifer Zimmermann, Hannah Rainer, Ann-Christine Junker, Sonja Wolfheimer, Stefan Vieths, Stephan Scheurer, Stefan Sch&#252;lke (2022). Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein . International Journal of Molecular Sciences.

et al., Zimmermann J, Goretzki A, Meier C, Wolfheimer S, Lin YJ, Rainer H, Krause M, Wedel S, Spies G, F&#252;hrer F (2022). Modulation of dendritic cell metabolism by an MPLA-adjuvanted allergen product for specific immunotherapy . Frontiers in immunology.

Goretzki A, Zimmermann J, Lin YJ, Sch&#252;lke S (2022). Immune Metabolism-An Opportunity to Better Understand Allergic Pathology and Improve Treatment of Allergic Diseases? . Frontiers in allergy.

Yen-Ju Lin, Adam Flaczyk, Sonja Wolfheimer, Alexandra Goretzki, Annette Jamin, Andrea Wangorsch, Stefan Vieths, Stephan Scheurer, Stefan Sch&#252;lke (2021). The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells . Cells.

Yen-Ju Lin and Alexandra Goretzki and Stefan Schülke(2021). Immune Metabolism of IL-4-Activated B Cells and Th2 Cells in the Context of Allergic Diseases . Frontiers in Immunology. 12. Frontiers Media {SA}

Yen-Ju Lin, Adam Flaczyk, Sonja Wolfheimer, Alexandra Goretzki, Annette Jamin, Andrea Wangorsch, Stefan Vieths, Stephan Scheurer, Stefan Sch&#252;lke (2021). The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE₂ from Epithelial Cells . Cells.

(2021). The Flagellin:Allergen Fusion Protein rFlaA:Betv1 Induces a MyD88- and MAPK-Dependent Activation of Glucose Metabolism in Macrophages . Cells.

Yen-Ju Lin, Garibald Papp, Csaba Miskey, Anna Fiedler, Alexandra Goretzki, Sonja Wolfheimer, Jennifer Zimmermann, Peter Crauwels, Zolt&#225;n Ivics, Ger van Zandbergen, et al. (2021). The Flagellin:Allergen Fusion Protein rFlaA:Betv1 Induces a MyD88− and MAPK-Dependent Activation of Glucose Metabolism in Macrophages . Cells.

(2021). β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex . Cells.

Yen-Ju Lin, Ting-Yu Cheng, Wataru Saburi, Stefan Vieths, Stephan Scheurer, Stefan Sch&#252;lke, Masako Toda (2021). β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex . Cells.

(2021). Immune metabolism in allergies, does it matter?-A review of immune metabolic basics and adaptations associated with the activation of innate immune cells in allergy . Allergy.

(2020). Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis . Cells.

Yen-Ju Lin, Martina Anzaghe, Stefan Sch&#252;lke (2020). Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis . Cells.