プロフィール詳細

プロジェクトを作成

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Yiqing W.に依頼

Denmark

Biomedical Scientist | PhD in Cellular & Genetic Medicine | Clinical-Trained | Protein Biochemistry & Molecular Biology

プロフィール概要

Postdoctoral Researcher (Københavns Universitet - University of Copenhagen, Denmark) Apr 2024 - Present • Finalizing first-author paper on TOP3A mutations and collaborating on protein degradation projects in disease-relevant cell models. • Contributing to method development and assay design with a focus on functional readouts. • Building experience in translational science and gaining exposure to innovation protection processes. PHD Graduate Student (Københavns Universitet - University of Copenhagen, Denmark) May 2020 - Apr 2024 • Led research on a rare genetic disorder involving DNA repair, using both cellular and biochemical approaches. • Characterized genetically modified mouse models through early embryo dissection and histological staining. • Carried out studies on genetically modified mouse models via embryonic dissections and functional stem cell assays. • Purified and analyzed disease-associated TOP3A protein variants using advanced HPLC methods (AFC, IEX, SEC). • Co-authored publications in peer-reviewed journals and presented at international conferences. • Developed strengths in scientific communication, interdisciplinary teamwork, and project ownership. Research Assistant (Københavns Universitet - University of Copenhagen, Denmark) Nov 2019 - Apr 2020 Copenhagen Municipality, Capital Region of Denmark, DenmarkCopenhagen Municipality, Capital Region of Denmark, Denmark • Investigated DNA damage responses in cancer models as part of a cross-lab collaboration. • Performed drug screening and live-cell imaging assays on mammalian cell lines. • Deepened practical skills in immunofluorescence and microscopic analysis. Medical Trainee (Clinical Rotations) (Xinhua Hospital affiliated to Shanghai Jiao Tong University, School of Medicine, China) Aug 2018 - Jun 2019 • Rotated through key clinical departments including internal medicine, surgery, oncology, and pediatrics. • Supported patient care through physical examinations, medical record documentation, and surgery prep. • Gained strong foundations in medical reasoning, time-sensitive teamwork, and patient communication. • This experience continues to shape me to approach scientific problems with real-world impact in mind. Master Thesis Student (CRCL Centre de Recherche en Cancérologie de Lyon, France) Sep 2017 - Jun 2018 • Researched epigenetic readers involved in breast cancer cell lines. • Gained hands-on lab experience in qPCR, western blotting, and immunofluorescence, and mammalian cell culture. • Authored and presented findings at internal seminars and developed my communication skills across language and culture contexts. Research Trainee, Pharmacology Dept. (Shanghai Jiao Tong University School of Medicine, China) Nov 2015 - Jun 2016 • Worked on protein purification and enzymatic assays related to pharmacological compounds. • Developed technical skills in HPLC purification, cloning, SDS-PAGE, and functional activity assays. • Learned to troubleshoot experiments independently and report findings clearly.

専門分野

• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ DNA Sequencing
• ☆ Mutagenesis
• ☆ Recombinant DNA
• ☆ Plasmid DNA
• ☆ DNA Damage & Repair
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cytogenetics
• ☆ Stem Cell Research
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Human Biology
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Carcinogenesis

サービス

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, General Proofreading & Editing, Translation

Research Fact Checking, Scientific and Technical Research

Consulting Scientific and Technical Consulting

Data & AI Data Visualization

職務経験

University of Copenhagen

11月 2019 - 現在

Medical intern

Shanghai Jiaotong University

8月 2018 - 6月 2019

Masters research student

Université Claude Bernard (Lyon I)

9月 2017 - 6月 2018

Masters research student

Shanghai Jiaotong University

11月 2015 - 6月 2016

学歴

PhD Molecular Medicine

University of Copenhagen

5月 2020 - 4月 2024

Bachelor's Degree in Clinical Medicine

Shanghai Jiaotong University - China

9月 2013 - 6月 2019

Masters in Cancer Biology

Université Claude Bernard (Lyon I) - France

9月 2017 - 6月 2018

認定資格

• Laboratory animal science (ABD)

  FELASA

  12月 2020 - 現在

出版物

JOURNAL ARTICLE

Yiqing Wang, Sebastian Kaiser, Javier Martin-Gonzalez, Yuan Li, Lene J. Rasmussen, Andres J. Lopez-Contreras, Anna H. Bizard, Ian D. Hickson (2025). Functional analysis of pathological mutations in DNA topoisomerase 3A . Cell Reports.

Yiqing Wang, Emil P. T. Hertz, Ignacio Alonso-de Vega, Thomas Kruse, Ivo A. Hendriks, Anna H. Bizard, Ania Eugui-Anta, Ronald T. Hay, Michael L. Nielsen, Jakob Nilsson, et al. (2023). The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure . Nature Structural & Molecular Biology.