プロフィール詳細

プロジェクトを作成

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Dr. Ziaullah Z.に依頼

United States

Freelance Regulatory Affairs Specialist for Drugs, and Medical Devices/Regulatory Writer, Drug Developer

プロフィール概要

Bridging the gap between complex chemical problem-solving and strategic regulatory navigation, I contribute to the development of innovative pharmaceuticals that meet the highest standards of safety and efficacy. With a strong foundation in organic chemistry and a nuanced understanding of drugs, biologics and medical devices regulations, I play a pivotal role in guiding drug substances from early-stage synthesis through to commercialization and regulatory approval.

専門分野

• ☆ Catalysis
• ☆ Biocatalysis
• ☆ Natural Product Chemistry
• ☆ Radiochemistry
• ☆ Green Chemistry
• ☆ Organic Chemistry
• ☆ Retrosynthesis
• ☆ Computational Chemistry
• ☆ Physical Organic Chemistry
• ☆ Flavor & Fragrance Chemistry
• ☆ Food Chemistry
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Medicinal Chemistry
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Biologic & Biosimilar Development
• ☆ Drug Substance Characterization
• ☆ Drug Stability Testing
• ☆ Preclinical ADME/PK/PD
• ☆ Drug-Drug Interactions
• ☆ Preclinical Research
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Antibiotic Development
• ☆ Bioavailability
• ☆ Pharmaceutical Manufacturing
• ☆ Extractable & Leachable Testing
• ☆ Pharmaceutical Process Development
• ☆ Bioprocess Development
• ☆ Small Molecule Manufacturing
• ☆ Biologic & Biosimilar Manufacturing
• ☆ Medical Devices
• ☆ Post-Market Surveillance
• ☆ Medical Device Marketing
• ☆ Medical Device Regulatory Consulting
• ☆ European Medical Device Regulation (MDR)
• ☆ ISO 13485
• ☆ ISO 14971
• ☆ EU In vitro Diagnostic Regulation (IVDR) Compliance
• ☆ In vitro Diagnostics
• ☆ In vitro Diagnostic Validation
• ☆ In vitro Diagnostic Design
• ☆ Biomarker Analysis
• ☆ Psychoactive Drugs
• ☆ Pharmaceutical Management
• ☆ Cosmetic & Personal Care Product Manufacturing
• ☆ Herbal Products
• ☆ Nutraceuticals
• ☆ Supplements
• ☆ Intellectual Property Law

サービス

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing, General Proofreading & Editing

Research Gap Analysis, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Go-to-Market Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting, Regulatory Consulting, Manufacturing Consulting

Data & AI Statistical Analysis, Data Processing

Product Development Stability/Shelf Life Testing, Product Evaluation, Product Validation, Manufacturing, Quality Assurance & Control (QA/QC), Product Compliance , Concept Development, Product Launch Support

職務経験

Senior Research Scientist and Compliance Specialist

Curia Global Inc.

8月 2022 - 現在

Senior Research Scientist

Curia Global Inc., Albany, New York

8月 2022 - 現在

Research Scientist

Appili Therapeutics (Canada)

11月 2016 - 4月 2019

Senior Research Scientist and QA specialist

Appili Therapeutics

11月 2016 - 4月 2019

Research Scientist

NeuroQuest Inc.

4月 2013 - 10月 2016

学歴

Master in Regulatory Affairs for Drugs, Biologics and Medical Devices (College of Professional studies)

Northeastern University

9月 2020 - 5月 2023

Post Doctorate (Dalhousie University)

Dalhousie University

2月 2011 - 4月 2013

Bioorganic Medicianl Chemistry

Karachi University

1月 2000 - 9月 2005

Ph.D./ Synthesis and synthetic Transformation of Heterocyclic Compound and Natural Products in Search of Useful Therapeutic Agents (HEJ Research Institute of Chemistry)

University of Karachi

4月 2000 - 8月 2005

認定資格

• Master in Regulatory Affairs for Drugs, Biologics and Medical Devices

  Northeastern University, Boston Massachusetts, US

  9月 2020 - 現在

出版物

JOURNAL ARTICLE

Ziaullah Ziaullah, Tasmeena Parveen, Ijaz Ahmad, Madeeha Aslam, Fozia Fozia, Ahmad Khushal, Mohamed Mohany, Salim S. Al-Rejaie, Marija Milošević, Leander Tapfer (2025). Green Synthesis of Pure and Zirconium‐Doped Cerium Oxide Nanoparticles Using Aqueous Extract of Sanvitalia procumbens, Its Characterization, Antiplatelet and Cytotoxic Activities . Nanomaterials and Nanotechnology.

Murad A. Mubaraki, Mubbashir Hussain, Faaiz Ul Hassan, Shahzad Munir, Fozia Fozia, Ijaz Ahmad, Fatima Bibi, Samia Sultan, Ziaullah Zialluh, Amitis Ramezani (2024). Antimicrobial Resistance and Associated Risk Factors for Clostridium difficile in Patients Attending Tertiary Care Settings . Journal of Tropical Medicine.

Ziaullah, Sumudu N. Warnakulasuriya, H.P. Vasantha Rupasinghe (2016). Novel long chain fatty acid derivatives of quercetin-3-O-glucoside reduce cytotoxicity induced by cigarette smoke toxicants in human fetal lung fibroblasts . European Journal of Pharmacology.

Ziaullah, Sumudu Warnakulasuriya, H. Rupasinghe (2016). Long Chain Fatty Acid Esters of Quercetin-3-O-glucoside Attenuate H2O2-induced Acute Cytotoxicity in Human Lung Fibroblasts and Primary Hepatocytes . Molecules.

Ziaullah, H.P. Vasantha Rupasinghe (2016). Sonochemical enzyme-catalyzed regioselective acylation of flavonoid glycosides . Bioorganic Chemistry.

Ziaullah Ziaullah, Satvir Sekhon-Loodu, H. P. Vasantha Rupasinghe, Yanwen Wang, Marianna Kulka, Fereidoon Shahidi (2015). Novel quercetin-3-O-glucoside eicosapentaenoic acid ester ameliorates inflammation and hyperlipidemia . Inflammopharmacology.

Ziaullah, Satvir Sekhon-Loodu, H.P. Vasantha Rupasinghe (2015). Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages . International Immunopharmacology.

Ziaullah, Sumudu Warnakulasuriya, H. Rupasinghe (2014). Long Chain Fatty Acid Acylated Derivatives of Quercetin-3-O-Glucoside as Antioxidants to Prevent Lipid Oxidation . Biomolecules.

Ziaullah, Sandhya V. G. Nair, H. P. Vasantha Rupasinghe (2014). Fatty Acid Esters of Phloridzin Induce Apoptosis of Human Liver Cancer Cells through Altered Gene Expression . PLoS ONE.

Ziaullah Ziaullah, Khushwant S Bhullar, Vasantha Rupasinghe (2014). In Vitro Regulation of Enzymes of the Renin-angiotensin-aldosterone System by Isoquercitrin, Phloridzin and their Long Chain Fatty Acid Derivatives . Functional Foods in Health and Disease.

Ziaullah, H.P. Vasantha Rupasinghe (2013). An efficient microwave-assisted enzyme-catalyzed regioselective synthesis of long chain acylated derivatives of flavonoid glycosides . Tetrahedron Letters.

Ziaullah, Khushwant S. Bhullar, Sumudu N. Warnakulasuriya, H.P. Vasantha Rupasinghe (2013). Biocatalytic synthesis, structural elucidation, antioxidant capacity and tyrosinase inhibition activity of long chain fatty acid acylated derivatives of phloridzin and isoquercitrin . Bioorganic & Medicinal Chemistry.

Khalid M. Khan, Abdul Wadood, Muhammad Ali, Zia-Ullah, Zaheer Ul-Haq, M. Arif Lodhi, Momin Khan, Shahnaz Perveen, M. Iqbal Choudhary (2010). Identification of potent urease inhibitors via ligand- and structure-based virtual screening and in vitro assays . Journal of Molecular Graphics and Modelling.

Muhammad Zareef, Rashid Iqbal, Khalid M. Khan, Javid H. Zaidi, Zia-Ullah, Muhammad Arfan (2009). A convenient synthesis of<i>p</i>-substituted 1-arylsulfonyl-pyrrolidin-2-ones . Natural Product Research.

Khalid M. Khan, Nosheen A. Rao, Zia-Ullah, Muhammad Ali, Shahnaz Perveen, Muhammad Iqbal Choudhary, Atta-Ur-Rahman, Wolfgang Voelter (2009). Facile, economical and direct synthesis of 9-anilinoacridines . Natural Product Research.

Khalid Mohammed Khan, Shahnaz Perveen, Safdar Hayat, Muhammad Ali, Wolfgang Voelter (2008). A convenient iodination method for alcohols using cesium iodide/methanesulfonic acid and its comparison using cesium iodide/<b> <i>p</i> </b>-toluenesulfonic acid or cesium iodide/aluminium chloride . Natural Product Research.

Wen Zhang, Karsten Krohn, Zia‐Ullah, Ulrich Fl&#246;rke, Gennaro Pescitelli, Lorenzo Di Bari, S&#225;ndor Antus, Tibor Kurt&#225;n, Joachim Rheinheimer, Siegfried Draeger, et al. (2008). New Mono‐ and Dimeric Members of the Secalonic Acid Family: Blennolides A–G Isolated from the Fungus <i>Blennoria</i> sp . Chemistry – A European Journal.

Khalid Mohammed Khan, Sumbul Ahmed, Zulfiqar Ali Khan, Zia-Ullah, Mubeen Rani, Muhammad Iqbal Choudhary, Shahnaz Perveen (2008). In Vitro Leishmanicidal Activity of 3-substituted Isocoumarins: Synthesis and Structure activity Relationship . Medicinal Chemistry.

Karsten Krohn, Zia‐Ullah, Hidayat Hussain, Ulrich Fl&#246;rke, Barbara Schulz, Siegfried Draeger, Gennaro Pescitelli, Piero Salvadori, S&#225;ndor Antus, Tibor Kurt&#225;n (2007). Massarilactones E‐G, new metabolites from the endophytic fungus <i>Coniothyrium</i> sp., associated with the plant <i>Artimisia maritima</i> . Chirality.

Khalid Mohammed Khan, Uzma Rasool Mughal, Mahmud Tareq Hassan Khan, Zia-Ullah, Shahnaz Perveen, Muhammad Iqbal Choudhary (2006). Oxazolones: New tyrosinase inhibitors; synthesis and their structure–activity relationships . Bioorganic &amp; Medicinal Chemistry.

Ulrich Fl&#246;rke, Karsten Krohn, Zia-Ullah, Hiayat Hussain (2006). An orthorhombic modification of (<i>R</i>)-(−)-8-hydroxy-3-methyl-3,4-dihydro-1<i>H</i>-2-benzopyran-1-one [(<i>R</i>)-(−)-mellein] . Acta Crystallographica Section E Structure Reports Online.

Khalid Mohammed Khan, Zia Ullah, Muhammad Arif Lodhi, Muhammad Ali, Muhammad Iqbal Choudhary, Atta ur Rahman, Zaheer ul Haq (2006). Successful computer guided planned synthesis of (4R)-thiazolidine carboxylic acid and its 2-substituted analogues as urease inhibitors . Molecular Diversity.

Khalid Mohammed Khan, Zia Nullah, Muhammad arif Lodhi, Saima Jalil, Muhammad Iqbal Choudhary, Atta-Ur- Rahman (2006). Synthesis and anti-inflammatory activity of some selected aminothiophene analogs . Journal of Enzyme Inhibition and Medicinal Chemistry.

K. Khan, Bentham Science Publisher Zia-Ullah, S. Perveen, G. Maharvi, S. Shah, N. Ambreen, M. Choudhary, Bentham Science Publisher Atta-ur-Rahman, W. Voelter (2005). A Convenient, Highly Versatile Iodination Method of Alcohols Using Cesium Iodide/p- Toluenesulphonic Acid . Letters in Organic Chemistry.

M. Mesaik, K. Khan, S. Rahat, Zia-Ullah Zia-Ullah, M. Choudhary, S. Murad, N. Abdullah, Atta-ur-Rahman Atta-ur-Rahman, A. Ahmad, R. Siddiqui (2005). Immunomodulatory Properties of Synthetic Imidazolone Derivatives . Letters in Drug Design &amp; Discovery.

Khalid Khan, Bentham Science Publisher Zia-Ullah, Shahnaz Perveen, M. Choudhary, Bentham Science Publisher Atta-ur-Rahman, Wolfgang Voelter (2005). A Convenient, Highly Selective Iodination Method for Alcohols Using Cesium Iodide/Aluminum Chloride . Letters in Organic Chemistry.

Khalid Mohammed Khan, Zafar S. Saify, Muhammad Zarrar Khan, Zia-Ullah, M. Iqbal Choudhary, Atta-ur-Rahman, Shahnaz Perveen, Zahid H. Chohan, Claudiu T. Supuran (2004). Synthesis of Coumarin Derivatives with Cytotoxic, Antibacterial and Antifungal Activity . Journal of Enzyme Inhibition and Medicinal Chemistry.

Muhammad A Mesaik, Shagufta Rahat, Khalid M Khan, Zia-Ullah, Muhammad I Choudhary, Shahnaz Murad, Zakiah Ismail, Atta-ur-Rahman, Aqeel Ahmad (2004). Synthesis and immunomodulatory properties of selected oxazolone derivatives . Bioorganic &amp; Medicinal Chemistry.

Khalid Mohammed Khan, Sajid Iqbal, Muhammad Arif Lodhi, Ghulam Murtaza Maharvi, Zia- Ullah, Muhammad Iqbal Choudhary, Atta-ur- Rahman, Shahnaz Perveen (2004). Biscoumarin: new class of urease inhibitors; economical synthesis and activity . Bioorganic &amp; Medicinal Chemistry.

Khalid Khan, Bentham Science Publisher Zia-Ullah, Mubeen Rani, Shahnaz Perveen, Syed Haider, Muhammad Choudhary, Bentham Science Publisher Atta-ur-Rahman, Wolfgang Voelter (2004). Microwave-Assisted Synthesis of 2,5-Disubstituted-1,3,4-Oxadiazoles . Letters in Organic Chemistry.

Javid H. Zaidi, Fazal Naeem, Khalid M. Khan, Rashid Iqbal, Zia‐Ullah (2004). Synthesis of Dithioacetals and Oxathioacetals with Chiral Auxiliaries . Synthetic Communications.

(2003). An Alternative Method for the Synthesis of γ-Lactones by Using Cesium Fluoride-Celite/Acetonitrile Combination . Synthetic Communications.

Khalid Mohammed Khan, Ghulam Murtaza Maharvi, Safdar Hayat, Zia-Ullah, M. Iqbal Choudhary, Atta-ur-Rahman (2003). An expedient esterification of aromatic carboxylic acids using sodium bromate and sodium hydrogen sulfite . Tetrahedron.

Safdar Hayat, Atta-ur-Rahman, Khalid Mohammed Khan, M. Iqbal Choudhary, Ghulam Murtaza Maharvi, Zia-Ullah, Ernst Bayer (2003). An Alternative Method for the Highly Selective Iodination of Alcohols Using a CsI/BF₃·Et₂O System . Synthetic Communications.

Khalid Mohammed Khan, Zafar S. Saify, Saeedan Begum, Fatima Noor, Muhammad Zarrar Khan, Safdar Hayat, M. Iqbal Choudhary, Shahnaz Perveen, Atta-Ur-Rahman, Zia-Ullah (2003). Synthesis and Biological Screening of 7-Hydroxy-4-Methyl-2 H -Chromen-2-One, 7-Hydroxy-4,5-Dimethyl-2 H -Chromen-2-One and their Some Derivatives . Natural Product Research.

BOOK CHAPTER

(2015). Application of NMR Spectroscopy in Plant Polyphenols Associated with Human Health . Applications of NMR Spectroscopy.

OTHER

Ziaullah Ziaullah Ph.D./ Synthesis and synthetic Transformation of Heterocyclic Compound and Natural Products in Search of Useful Therapeutic Agents .